5vqh - Revision history

OCA at 13:55, 4 October 2023

OCA — Wed, 04 Oct 2023 13:55:25 GMT

←Older revision		Revision as of 13:55, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='5vqh' size='340' side='right'caption='[[5vqh]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='5vqh' size='340' side='right'caption='[[5vqh]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5vqh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bommo Bommo~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VQH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5vqh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VQH FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=2MR:N3~~,~~+N4-DIMETHYLARGININE'>2MR</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~PAPI ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7091 BOMMO])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqh OCA], [https://pdbe.org/5vqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vqh RCSB], [https://www.ebi.ac.uk/pdbsum/5vqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqh OCA], [https://pdbe.org/5vqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vqh RCSB], [https://www.ebi.ac.uk/pdbsum/5vqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/TDRKH_BOMMO TDRKH_BOMMO]] Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (PubMed:23970546, PubMed:26919431). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins (Siwi or Ago3) and govern the methylation and subsequent repression of transposons (PubMed:23970546, PubMed:26919431). Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs: acts by recruiting the exonuclease PNLDC1/trimmer to Siwi-bound pre-piRNAs (PubMed:26919431).<ref>PMID:23970546</ref> <ref>PMID:26919431</ref>	+	[https://www.uniprot.org/uniprot/TDRKH_BOMMO TDRKH_BOMMO] Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (PubMed:23970546, PubMed:26919431). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins (Siwi or Ago3) and govern the methylation and subsequent repression of transposons (PubMed:23970546, PubMed:26919431). Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs: acts by recruiting the exonuclease PNLDC1/trimmer to Siwi-bound pre-piRNAs (PubMed:26919431).<ref>PMID:23970546</ref> <ref>PMID:26919431</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bommo~~]]	+	[[Category: Bombyx mori]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Honda, S]]	+	[[Category: Honda S]]
-	[[Category: Hubbard~~, P A~~]]	+	[[Category: Hubbard PA]]
-	[[Category: Kirino, Y]]	+	[[Category: Kirino Y]]
-	[[Category: McNally, R]]	+	[[Category: McNally R]]
-	[[Category: Murali, R]]	+	[[Category: Murali R]]
-	[[Category: Ohtaki, A]]	+	[[Category: Ohtaki A]]
-	[[Category: Pan, X]]	+	[[Category: Pan X]]
-	~~[[Category: Bmpapi]]~~	+
-	~~[[Category: Rna binding protein]]~~	+
-	~~[[Category: Sdma]]~~	+
-	~~[[Category: Tudor~~]]	+

OCA at 17:40, 10 March 2021

OCA — Wed, 10 Mar 2021 17:40:29 GMT

←Older revision		Revision as of 17:40, 10 March 2021
Line 3:		Line 3:
	<StructureSection load='5vqh' size='340' side='right'caption='[[5vqh]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='5vqh' size='340' side='right'caption='[[5vqh]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5vqh]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bommo Bommo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5VQH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5vqh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bommo Bommo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VQH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PAPI ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7091 BOMMO])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PAPI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7091 BOMMO])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5vqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqh OCA], [~~http~~://pdbe.org/5vqh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5vqh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5vqh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqh OCA], [https://pdbe.org/5vqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vqh RCSB], [https://www.ebi.ac.uk/pdbsum/5vqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/TDRKH_BOMMO TDRKH_BOMMO]] Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (PubMed:23970546, PubMed:26919431). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins (Siwi or Ago3) and govern the methylation and subsequent repression of transposons (PubMed:23970546, PubMed:26919431). Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs: acts by recruiting the exonuclease PNLDC1/trimmer to Siwi-bound pre-piRNAs (PubMed:26919431).<ref>PMID:23970546</ref> <ref>PMID:26919431</ref>	+	[[https://www.uniprot.org/uniprot/TDRKH_BOMMO TDRKH_BOMMO]] Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (PubMed:23970546, PubMed:26919431). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins (Siwi or Ago3) and govern the methylation and subsequent repression of transposons (PubMed:23970546, PubMed:26919431). Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs: acts by recruiting the exonuclease PNLDC1/trimmer to Siwi-bound pre-piRNAs (PubMed:26919431).<ref>PMID:23970546</ref> <ref>PMID:26919431</ref>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:38, 1 January 2020

OCA — Wed, 01 Jan 2020 09:38:39 GMT

←Older revision		Revision as of 09:38, 1 January 2020
Line 1:		Line 1:

	==Crystal structure of the extended Tudor domain from BmPAPI in complex with sDMA==		==Crystal structure of the extended Tudor domain from BmPAPI in complex with sDMA==
-	<StructureSection load='5vqh' size='340' side='right' caption='[[5vqh]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='5vqh' size='340' side='right'caption='[[5vqh]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5vqh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VQH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5vqh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bommo Bommo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VQH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PAPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7091 BOMMO])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqh OCA], [http://pdbe.org/5vqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vqh RCSB], [http://www.ebi.ac.uk/pdbsum/5vqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqh OCA], [http://pdbe.org/5vqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vqh RCSB], [http://www.ebi.ac.uk/pdbsum/5vqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqh ProSAT]</span></td></tr>
	</table>		</table>
Line 13:		Line 14:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bommo]]
		+	[[Category: Large Structures]]
	[[Category: Honda, S]]		[[Category: Honda, S]]
	[[Category: Hubbard, P A]]		[[Category: Hubbard, P A]]

OCA at 08:34, 6 October 2017

OCA — Fri, 06 Oct 2017 08:34:36 GMT

←Older revision		Revision as of 08:34, 6 October 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5vqh is ~~ON HOLD~~	+	==Crystal structure of the extended Tudor domain from BmPAPI in complex with sDMA==
-		+	<StructureSection load='5vqh' size='340' side='right' caption='[[5vqh]], [[Resolution\|resolution]] 2.40Å' scene=''>
-	~~Authors~~: ~~Hubbard~~, P.A., ~~Pan~~, X., ~~Ohtaki~~, A., ~~McNally~~, R., Honda, S., Kirino, Y~~., Murali, R.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5vqh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VQH FirstGlance]. <br>
-	~~Description: Crystal structure of the extended Tudor domain from BmPAPI in complex with sDMA~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqh OCA], [http://pdbe.org/5vqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vqh RCSB], [http://www.ebi.ac.uk/pdbsum/5vqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqh ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TDRKH_BOMMO TDRKH_BOMMO]] Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (PubMed:23970546, PubMed:26919431). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins (Siwi or Ago3) and govern the methylation and subsequent repression of transposons (PubMed:23970546, PubMed:26919431). Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs: acts by recruiting the exonuclease PNLDC1/trimmer to Siwi-bound pre-piRNAs (PubMed:26919431).<ref>PMID:23970546</ref> <ref>PMID:26919431</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Honda, S]]
		+	[[Category: Hubbard, P A]]
		+	[[Category: Kirino, Y]]
		+	[[Category: McNally, R]]
	[[Category: Murali, R]]		[[Category: Murali, R]]
-	[[Category: ~~Hubbard~~, P.A]]	+	[[Category: Ohtaki, A]]
	[[Category: Pan, X]]		[[Category: Pan, X]]
-	[[Category: ~~Kirino, Y~~]]	+	[[Category: Bmpapi]]
-	[[Category: ~~Ohtaki, A~~]]	+	[[Category: Rna binding protein]]
-	[[Category: ~~Mcnally, R~~]]	+	[[Category: Sdma]]
-	[[Category: ~~Honda, S~~]]	+	[[Category: Tudor]]

OCA at 11:43, 24 May 2017

OCA — Wed, 24 May 2017 11:43:49 GMT

←Older revision		Revision as of 11:43, 24 May 2017
Line 3:		Line 3:
	The entry 5vqh is ON HOLD		The entry 5vqh is ON HOLD

-	Authors: ~~Paul~~ A. ~~Hubbard~~, ~~Xinlei~~ Pan, ~~Akashi~~ Ohtaki, ~~Randall~~ McNally, ~~Shozo~~ Honda, ~~Yohei~~ Kirino, ~~Ramachandran~~ Murali	+	Authors: Hubbard, P.A., Pan, X., Ohtaki, A., McNally, R., Honda, S., Kirino, Y., Murali, R.

	Description: Crystal structure of the extended Tudor domain from BmPAPI in complex with sDMA		Description: Crystal structure of the extended Tudor domain from BmPAPI in complex with sDMA
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Paul A.~~ Hubbard, ~~Xinlei~~ Pan, ~~Akashi~~ Ohtaki, ~~Randall~~ Mcnally, ~~Shozo~~ Honda, ~~Yohei Kirino, Ramachandran Murali~~]]	+	[[Category: Murali, R]]
		+	[[Category: Hubbard, P.A]]
		+	[[Category: Pan, X]]
		+	[[Category: Kirino, Y]]
		+	[[Category: Ohtaki, A]]
		+	[[Category: Mcnally, R]]
		+	[[Category: Honda, S]]

OCA: Protected "5vqh" [edit=sysop:move=sysop]

OCA — Wed, 17 May 2017 14:07:11 GMT

Protected "5vqh" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:07, 17 May 2017

OCA: New page: '''Unreleased structure''' The entry 5vqh is ON HOLD Authors: Paul A. Hubbard, Xinlei Pan, Akashi Ohtaki, Randall McNally, Shozo Honda, Yohei Kirino, Ramachandran Murali Description: C...

OCA — Wed, 17 May 2017 14:07:10 GMT

New page: '''Unreleased structure''' The entry 5vqh is ON HOLD Authors: Paul A. Hubbard, Xinlei Pan, Akashi Ohtaki, Randall McNally, Shozo Honda, Yohei Kirino, Ramachandran Murali Description: C...

New page

'''Unreleased structure'''

The entry 5vqh is ON HOLD

Authors: Paul A. Hubbard, Xinlei Pan, Akashi Ohtaki, Randall McNally, Shozo Honda, Yohei Kirino, Ramachandran Murali

Description: Crystal structure of the extended Tudor domain from BmPAPI in complex with sDMA
[[Category: Unreleased Structures]]
[[Category: Paul A. Hubbard, Xinlei Pan, Akashi Ohtaki, Randall Mcnally, Shozo Honda, Yohei Kirino, Ramachandran Murali]]