5vxl - Revision history

OCA at 14:01, 4 October 2023

OCA — Wed, 04 Oct 2023 14:01:54 GMT

←Older revision		Revision as of 14:01, 4 October 2023
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	<StructureSection load='5vxl' size='340' side='right'caption='[[5vxl]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='5vxl' size='340' side='right'caption='[[5vxl]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5vxl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5VXL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5vxl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VXL FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5vxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxl OCA], [~~http~~://pdbe.org/5vxl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5vxl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5vxl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxl ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxl OCA], [https://pdbe.org/5vxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vxl RCSB], [https://www.ebi.ac.uk/pdbsum/5vxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/IPAD_SHIFL IPAD_SHIFL]] Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.<ref>PMID:7957095</ref> <ref>PMID:15731041</ref>	+	[https://www.uniprot.org/uniprot/IPAD_SHIFL IPAD_SHIFL] Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.<ref>PMID:7957095</ref> <ref>PMID:15731041</ref>

	==See Also==		==See Also==
Line 17:		Line 18:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Barta, M L~~]]	+	[[Category: Shigella flexneri]]
-	[[Category: ~~Battaile, K P~~]]	+	[[Category: Vicugna pacos]]
-	[[Category: ~~Lovell, S~~]]	+	[[Category: Barta ML]]
-	[[Category: ~~Picking, W D~~]]	+	[[Category: Battaile KP]]
-	[[Category: ~~Picking, W L~~]]	+	[[Category: Lovell S]]
-	[[Category: ~~Immune system~~]]	+	[[Category: Picking WD]]
-	[[Category: ~~T3ss]]~~	+	[[Category: Picking WL]]
-	~~[[Category: Tip protein]]~~	+
-	~~[[Category: Vhh~~]]	+

OCA at 08:45, 30 September 2020

OCA — Wed, 30 Sep 2020 08:45:25 GMT

←Older revision		Revision as of 08:45, 30 September 2020
Line 1:		Line 1:

	==2.80 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JPS-G3==		==2.80 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JPS-G3==
-	<StructureSection load='5vxl' size='340' side='right' caption='[[5vxl]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='5vxl' size='340' side='right'caption='[[5vxl]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5vxl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXL OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5VXL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5vxl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5VXL FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5vxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxl OCA], [http://pdbe.org/5vxl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxl RCSB], [http://www.ebi.ac.uk/pdbsum/5vxl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxl ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5vxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxl OCA], [http://pdbe.org/5vxl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxl RCSB], [http://www.ebi.ac.uk/pdbsum/5vxl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/IPAD_SHIFL IPAD_SHIFL]] Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.<ref>PMID:7957095</ref> <ref>PMID:15731041</ref>		[[http://www.uniprot.org/uniprot/IPAD_SHIFL IPAD_SHIFL]] Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.<ref>PMID:7957095</ref> <ref>PMID:15731041</ref>
		+
		+	==See Also==
		+	*[[Antibody 3D structures\|Antibody 3D structures]]
		+	*[[3D structures of non-human antibody\|3D structures of non-human antibody]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Barta, M L]]		[[Category: Barta, M L]]
	[[Category: Battaile, K P]]		[[Category: Battaile, K P]]

OCA: Protected "5vxl" [edit=sysop:move=sysop]

OCA — Tue, 05 Sep 2017 14:52:49 GMT

Protected "5vxl" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:52, 5 September 2017

OCA: New page: ==2.80 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JPS-G3== == Structural highlights ==
<table><tr><td colspan='2'>[[5vxl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VXL FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxl OCA], [http://pdbe.org/5vxl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxl RCSB], [http://www.ebi.ac.uk/pdbsum/5vxl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxl ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/IPAD_SHIFL IPAD_SHIFL]] Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.<ref>PMID:7957095</ref> <ref>PMID:15731041</ref>
== References ==
<references/>
TOC
</StructureSection>
[[Category: Barta, M L]]
[[Category: Battaile, K P]]
[[Category: Lovell, S]]
[[Category: Picking, W D]]
[[Category: Picking, W L]]
[[Category: Immune system]]
[[Category: T3ss]]
[[Category: Tip protein]]
[[Category: Vhh]]