5wd9 - Revision history

OCA at 14:15, 13 March 2024

OCA — Wed, 13 Mar 2024 14:15:21 GMT

←Older revision		Revision as of 14:15, 13 March 2024
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	<StructureSection load='5wd9' size='340' side='right'caption='[[5wd9]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='5wd9' size='340' side='right'caption='[[5wd9]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5wd9]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Legionella_pneumophila_subsp.~~_pneumophila_570-co-h~~ Legionella pneumophila subsp. pneumophila ~~570-co-h~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WD9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5WD9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5wd9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_ATCC_43290 Legionella pneumophila subsp. pneumophila ATCC 43290]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WD9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WD9 FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~lp12_2320 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=933093 Legionella pneumophila subsp. pneumophila 570-CO-H])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5wd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wd9 OCA], [~~http~~://pdbe.org/5wd9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5wd9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5wd9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5wd9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wd9 OCA], [https://pdbe.org/5wd9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wd9 RCSB], [https://www.ebi.ac.uk/pdbsum/5wd9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wd9 ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Legionella pneumophila is a pathogen causing severe pneumonia in humans called Legionnaires' disease. Lem22 is a previously uncharacterized effector protein conserved in multiple Legionella strains. Here, we report the crystal structure of Lem22 from the Philadelphia strain, also known as lpg2328, at 1.40 A resolution. The structure shows an up-and-down three-helical bundle with a significant structural similarity to a number of protein-binding domains involved in apoptosis and membrane trafficking. Sequence conservation identifies a putative functional site on the interface of helices 2 and 3. The structure is an important step toward a functional characterization of Lem22.
-
-	Crystal structure of the Legionella effector Lem22.,Kozlov G, Wong K, Gehring K Proteins. 2017 Nov 21. doi: 10.1002/prot.25427. PMID:29159828<ref>PMID:29159828</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5wd9" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Legionella pneumophila subsp. pneumophila ~~570-co-h]]~~	+	[[Category: Legionella pneumophila subsp. pneumophila ATCC 43290]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Gehring K]]
-	[[Category: Gehring, K]]	+	[[Category: Kozlov G]]
-	[[Category: Kozlov, G]]	+	[[Category: Wong K]]
-	[[Category: Wong, K]]	+
-	~~[[Category: Bacterial effector]]~~	+
-	~~[[Category: Bsgi]]~~	+
-	~~[[Category: Legionella]]~~	+
-	~~[[Category: Protein binding~~]]	+

OCA at 08:29, 8 January 2020

OCA — Wed, 08 Jan 2020 08:29:39 GMT

←Older revision		Revision as of 08:29, 8 January 2020
Line 1:		Line 1:

	==Crystal structure of Legionella pneumophila effector lpg2328==		==Crystal structure of Legionella pneumophila effector lpg2328==
-	<StructureSection load='5wd9' size='340' side='right' caption='[[5wd9]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='5wd9' size='340' side='right'caption='[[5wd9]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5wd9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_570-co-h Legionella pneumophila subsp. pneumophila 570-co-h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WD9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WD9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[5wd9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_570-co-h Legionella pneumophila subsp. pneumophila 570-co-h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WD9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WD9 FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Legionella pneumophila subsp. pneumophila 570-co-h]]		[[Category: Legionella pneumophila subsp. pneumophila 570-co-h]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 07:34, 13 December 2017

OCA — Wed, 13 Dec 2017 07:34:52 GMT

←Older revision		Revision as of 07:34, 13 December 2017
Line 3:		Line 3:
	<StructureSection load='5wd9' size='340' side='right' caption='[[5wd9]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='5wd9' size='340' side='right' caption='[[5wd9]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5wd9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WD9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WD9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5wd9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_570-co-h Legionella pneumophila subsp. pneumophila 570-co-h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WD9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WD9 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wd9 OCA], [http://pdbe.org/5wd9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wd9 RCSB], [http://www.ebi.ac.uk/pdbsum/5wd9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wd9 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lp12_2320 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=933093 Legionella pneumophila subsp. pneumophila 570-CO-H])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wd9 OCA], [http://pdbe.org/5wd9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wd9 RCSB], [http://www.ebi.ac.uk/pdbsum/5wd9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wd9 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Legionella pneumophila is a pathogen causing severe pneumonia in humans called Legionnaires' disease. Lem22 is a previously uncharacterized effector protein conserved in multiple Legionella strains. Here, we report the crystal structure of Lem22 from the Philadelphia strain, also known as lpg2328, at 1.40 A resolution. The structure shows an up-and-down three-helical bundle with a significant structural similarity to a number of protein-binding domains involved in apoptosis and membrane trafficking. Sequence conservation identifies a putative functional site on the interface of helices 2 and 3. The structure is an important step toward a functional characterization of Lem22.
		+
		+	Crystal structure of the Legionella effector Lem22.,Kozlov G, Wong K, Gehring K Proteins. 2017 Nov 21. doi: 10.1002/prot.25427. PMID:29159828<ref>PMID:29159828</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5wd9" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Legionella pneumophila subsp. pneumophila 570-co-h]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Gehring, K]]		[[Category: Gehring, K]]

OCA at 06:12, 29 November 2017

OCA — Wed, 29 Nov 2017 06:12:16 GMT

←Older revision		Revision as of 06:12, 29 November 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5wd9 ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of Legionella pneumophila effector lpg2328==
-		+	<StructureSection load='5wd9' size='340' side='right' caption='[[5wd9]], [[Resolution\|resolution]] 1.40Å' scene=''>
-	~~Authors~~: ~~Kozlov~~, G., ~~Wong~~, K., ~~Gehring, K~~., ~~Montreal~~-~~Kingston Bacterial Structural Genomics Initiative (BSGI)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5wd9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WD9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WD9 FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of Legionella pneumophila effector lpg2328~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wd9 OCA], [http://pdbe.org/5wd9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wd9 RCSB], [http://www.ebi.ac.uk/pdbsum/5wd9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wd9 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Structural genomic]]
		+	[[Category: Gehring, K]]
	[[Category: Kozlov, G]]		[[Category: Kozlov, G]]
-	[[Category: Gehring, K]]
-	[[Category: Montreal-Kingston Bacterial Structural Genomics Initiative (Bsgi)]]
	[[Category: Wong, K]]		[[Category: Wong, K]]
		+	[[Category: Bacterial effector]]
		+	[[Category: Bsgi]]
		+	[[Category: Legionella]]
		+	[[Category: Protein binding]]

OCA at 05:19, 11 October 2017

OCA — Wed, 11 Oct 2017 05:19:55 GMT

←Older revision		Revision as of 05:19, 11 October 2017
Line 3:		Line 3:
	The entry 5wd9 is ON HOLD until Paper Publication		The entry 5wd9 is ON HOLD until Paper Publication

-	Authors:	+	Authors: Kozlov, G., Wong, K., Gehring, K., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)

-	Description:	+	Description: Crystal structure of Legionella pneumophila effector lpg2328
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Kozlov, G]]
		+	[[Category: Gehring, K]]
		+	[[Category: Montreal-Kingston Bacterial Structural Genomics Initiative (Bsgi)]]
		+	[[Category: Wong, K]]

OCA: Protected "5wd9" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 14:42:16 GMT

Protected "5wd9" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:42, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5wd9 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Wed, 27 Sep 2017 14:42:15 GMT

New page: '''Unreleased structure''' The entry 5wd9 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5wd9 is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]