5wud - Revision history

OCA at 16:54, 8 November 2023

OCA — Wed, 08 Nov 2023 16:54:27 GMT

←Older revision		Revision as of 16:54, 8 November 2023
Line 1:		Line 1:

	==Structural basis for conductance through TRIC cation channels==		==Structural basis for conductance through TRIC cation channels==
-	<StructureSection load='5wud' size='340' side='right' caption='[[5wud]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5wud' size='340' side='right'caption='[[5wud]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5wud]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_33909 Atcc 33909~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WUD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5WUD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5wud]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_acidocaldarius Sulfolobus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WUD FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5wuc\|5wuc]]~~, [[~~5wue~~\|~~5wue]], [[5wuf\|5wuf~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~ATY89_00310, ATZ20_03355 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=2285 ATCC 33909])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wud OCA], [https://pdbe.org/5wud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wud RCSB], [https://www.ebi.ac.uk/pdbsum/5wud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wud ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wud OCA], [~~http~~://pdbe.org/5wud PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5wud RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5wud PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5wud ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0U3H1E6_9CREN A0A0U3H1E6_9CREN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 33909~~]]	+	[[Category: Large Structures]]
-	[[Category: Bruni, R]]	+	[[Category: Sulfolobus acidocaldarius]]
-	[[Category: Chen~~, Y H~~]]	+	[[Category: Bruni R]]
-	[[Category: Gao, F]]	+	[[Category: Chen YH]]
-	[[Category: Guo~~, Y Z~~]]	+	[[Category: Gao F]]
-	[[Category: Hendrickson~~, W A~~]]	+	[[Category: Guo YZ]]
-	[[Category: Kloss, B]]	+	[[Category: Hendrickson WA]]
-	[[Category: Li~~, D L~~]]	+	[[Category: Kloss B]]
-	[[Category: Mao, Y]]	+	[[Category: Li DL]]
-	~~[[Category: NYCOMPS, New York Consortium on Membrane Protein Structure~~]]	+	[[Category: Mao Y]]
-	[[Category: Su, M]]	+	[[Category: Su M]]
-	[[Category: Wang~~, X H]]~~	+	[[Category: Wang XH]]
-	~~[[Category: Cation channel]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: New york consortium on membrane protein structure]]~~	+
-	~~[[Category: Nycomp]]~~	+
-	~~[[Category: Psi-biology]]~~	+
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Tric~~]]	+

OCA at 09:08, 16 November 2017

OCA — Thu, 16 Nov 2017 09:08:02 GMT

←Older revision		Revision as of 09:08, 16 November 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5wud is ~~ON HOLD until Paper~~ Publication	+	==Structural basis for conductance through TRIC cation channels==
		+	<StructureSection load='5wud' size='340' side='right' caption='[[5wud]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5wud]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33909 Atcc 33909]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WUD FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5wuc\|5wuc]], [[5wue\|5wue]], [[5wuf\|5wuf]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ATY89_00310, ATZ20_03355 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2285 ATCC 33909])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wud OCA], [http://pdbe.org/5wud PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wud RCSB], [http://www.ebi.ac.uk/pdbsum/5wud PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wud ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Mammalian TRICs function as K+-permeable cation channels that provide counter ions for Ca2+ handling in intracellular stores. Here we describe the structures of two prokaryotic homologues, archaeal SaTRIC and bacterial CpTRIC, showing that TRIC channels are symmetrical trimers with transmembrane pores through each protomer. Each pore holds a string of water molecules centred at kinked helices in two inverted-repeat triple-helix bundles (THBs). The pores are locked in a closed state by a hydrogen bond network at the C terminus of the THBs, which is lost when the pores assume an open conformation. The transition between the open and close states seems to be mediated by cation binding to conserved residues along the three-fold axis. Electrophysiology and mutagenesis studies show that prokaryotic TRICs have similar functional properties to those of mammalian TRICs and implicate the three-fold axis in the allosteric regulation of the channel.

-	~~Authors~~:	+	Structural basis for conductance through TRIC cation channels.,Su M, Gao F, Yuan Q, Mao Y, Li DL, Guo Y, Yang C, Wang XH, Bruni R, Kloss B, Zhao H, Zeng Y, Zhang FB, Marks AR, Hendrickson WA, Chen YH Nat Commun. 2017 May 19;8:15103. doi: 10.1038/ncomms15103. PMID:28524849<ref>PMID:28524849</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5wud" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Atcc 33909]]
		+	[[Category: Bruni, R]]
		+	[[Category: Chen, Y H]]
		+	[[Category: Gao, F]]
		+	[[Category: Guo, Y Z]]
		+	[[Category: Hendrickson, W A]]
		+	[[Category: Kloss, B]]
		+	[[Category: Li, D L]]
		+	[[Category: Mao, Y]]
		+	[[Category: NYCOMPS, New York Consortium on Membrane Protein Structure]]
		+	[[Category: Su, M]]
		+	[[Category: Wang, X H]]
		+	[[Category: Cation channel]]
		+	[[Category: Membrane protein]]
		+	[[Category: New york consortium on membrane protein structure]]
		+	[[Category: Nycomp]]
		+	[[Category: Psi-biology]]
		+	[[Category: Structural genomic]]
		+	[[Category: Tric]]

OCA at 12:00, 5 April 2017

OCA — Wed, 05 Apr 2017 12:00:24 GMT

←Older revision		Revision as of 12:00, 5 April 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5wud is ON HOLD	+	The entry 5wud is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5wud" [edit=sysop:move=sysop]

OCA — Mon, 02 Jan 2017 15:29:21 GMT

Protected "5wud" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:29, 2 January 2017

OCA: New page: '''Unreleased structure''' The entry 5wud is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Mon, 02 Jan 2017 15:29:20 GMT

New page: '''Unreleased structure''' The entry 5wud is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5wud is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]