5wzh - Revision history

OCA at 07:51, 22 November 2023

OCA — Wed, 22 Nov 2023 07:51:53 GMT

←Older revision		Revision as of 07:51, 22 November 2023
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	==Structure of APUM23-GGAAUUGACGG==		==Structure of APUM23-GGAAUUGACGG==
-	<StructureSection load='5wzh' size='340' side='right' caption='[[5wzh]], [[Resolution\|resolution]] 2.51Å' scene=''>	+	<StructureSection load='5wzh' size='340' side='right'caption='[[5wzh]], [[Resolution\|resolution]] 2.51Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5wzh]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WZH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5WZH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5wzh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WZH FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5wzg\|5wzg]], [[5wzi\|5wzi]], [[5wzj\|5wzj]], [[5wzk\|5wzk]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.509Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">APUM23, At1g72320, T10D10~~.~~21, T9N14.7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=3702 ARATH])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wzh OCA], [https://pdbe.org/5wzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wzh RCSB], [https://www.ebi.ac.uk/pdbsum/5wzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wzh ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5wzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wzh OCA], [~~http~~://pdbe.org/5wzh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5wzh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5wzh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5wzh ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PUM23_ARATH PUM23_ARATH]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.	+	[https://www.uniprot.org/uniprot/PUM23_ARATH PUM23_ARATH] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
-	[[Category: ~~Bao, H~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Jiang, Y~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Shi, Y~~]]	+	[[Category: Bao H]]
-	[[Category: ~~Wang, C~~]]	+	[[Category: Jiang Y]]
-	[[Category: ~~Wang, N~~]]	+	[[Category: Shi Y]]
-	[[Category: ~~Wu, J~~]]	+	[[Category: Wang C]]
-	[[Category: ~~Hydrolase~~]]	+	[[Category: Wang N]]
-	[[Category: ~~Rna binding protein-rna complex]]~~	+	[[Category: Wu J]]
-	~~[[Category: Signaling protein~~]]	+

OCA at 07:51, 6 December 2017

OCA — Wed, 06 Dec 2017 07:51:37 GMT

←Older revision		Revision as of 07:51, 6 December 2017
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	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/PUM23_ARATH PUM23_ARATH]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.		[[http://www.uniprot.org/uniprot/PUM23_ARATH PUM23_ARATH]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	PUF (Pumilio/fem-3 mRNA binding factor) proteins, a conserved family of RNA-binding proteins, recognize specific single-strand RNA targets in a specific modular way. Although plants have a greater number of PUF protein members than do animal and fungal systems, they have been the subject of fewer structural and functional investigations. The aim of this study was to elucidate the involvement of APUM23, a nucleolar PUF protein in the plant Arabidopsis, in pre-rRNA processing. APUM23 is distinct from classical PUF family proteins, which are located in the cytoplasm and bind to 3'UTRs of mRNA to modulate mRNA expression and localization. We found that the complete RNA target sequence of APUM23 comprises 11 nt in 18S rRNA at positions 1141-1151. The complex structure shows that APUM23 has 10 PUF repeats; it assembles into a C-shape, with an insertion located within the inner concave surface. We found several different RNA recognition features. A notable structural feature of APUM23 is an insertion in the third PUF repeat that participates in nucleotide recognition and maintains the correct conformation of the target RNA. Our findings elucidate the mechanism for APUM23's-specific recognition of 18S rRNA.
		+
		+	Structural basis for the specific recognition of 18S rRNA by APUM23.,Bao H, Wang N, Wang C, Jiang Y, Liu J, Xu L, Wu J, Shi Y Nucleic Acids Res. 2017 Nov 16;45(20):12005-12014. doi: 10.1093/nar/gkx872. PMID:29036323<ref>PMID:29036323</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5wzh" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:49, 6 November 2017

OCA — Mon, 06 Nov 2017 11:49:00 GMT

←Older revision		Revision as of 11:49, 6 November 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5wzh is ~~ON HOLD until Paper Publication~~	+	==Structure of APUM23-GGAAUUGACGG==
-		+	<StructureSection load='5wzh' size='340' side='right' caption='[[5wzh]], [[Resolution\|resolution]] 2.51Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5wzh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WZH FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5wzg\|5wzg]], [[5wzi\|5wzi]], [[5wzj\|5wzj]], [[5wzk\|5wzk]]</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">APUM23, At1g72320, T10D10.21, T9N14.7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wzh OCA], [http://pdbe.org/5wzh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wzh RCSB], [http://www.ebi.ac.uk/pdbsum/5wzh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wzh ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PUM23_ARATH PUM23_ARATH]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Arath]]
		+	[[Category: Bao, H]]
		+	[[Category: Jiang, Y]]
		+	[[Category: Shi, Y]]
		+	[[Category: Wang, C]]
		+	[[Category: Wang, N]]
		+	[[Category: Wu, J]]
		+	[[Category: Hydrolase]]
		+	[[Category: Rna binding protein-rna complex]]
		+	[[Category: Signaling protein]]

OCA at 17:06, 1 February 2017

OCA — Wed, 01 Feb 2017 17:06:41 GMT

←Older revision		Revision as of 17:06, 1 February 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5wzh is ON HOLD	+	The entry 5wzh is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5wzh" [edit=sysop:move=sysop]

OCA — Wed, 25 Jan 2017 22:38:07 GMT

Protected "5wzh" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:38, 25 January 2017

OCA: New page: '''Unreleased structure''' The entry 5wzh is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 25 Jan 2017 22:38:05 GMT

New page: '''Unreleased structure''' The entry 5wzh is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5wzh is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]