5x8w - Revision history

OCA at 07:55, 22 November 2023

OCA — Wed, 22 Nov 2023 07:55:56 GMT

←Older revision		Revision as of 07:55, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='5x8w' size='340' side='right'caption='[[5x8w]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5x8w' size='340' side='right'caption='[[5x8w]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5x8w]] is a 2 chain structure with sequence from [~~http://en.wikipedia.org/wiki/Human Human] and [http~~://en.wikipedia.org/wiki/~~Hylobates_concolor_leucogenys Hylobates concolor leucogenys~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8W OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5X8W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5x8w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X8W FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5x8u\|5x8u]], [[5x8s\|5x8s]], [[5x8x\|5x8x]], [[5x8q\|5x8q]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]</b></td><td class="sblockDat">RORC, NR1F3, RORG, RZRG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=61853 Hylobates concolor leucogenys]), NCOA1, BHLHE74, SRC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8w OCA], [https://pdbe.org/5x8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x8w RCSB], [https://www.ebi.ac.uk/pdbsum/5x8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8w ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3~~.1.48 2.3.1.48] </span>~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5x8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8w OCA], [~~http~~://pdbe.org/5x8w PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5x8w RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5x8w PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8w ProSAT]</span></td></tr>	+
	</table>		</table>
-	== Disease ==
-	[[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Note=A chromosomal aberration involving NCOA1 is a cause of rhabdomyosarcoma. Translocation t(2;2)(q35;p23) with PAX3 generates the NCOA1-PAX3 oncogene consisting of the N-terminus part of PAX3 and the C-terminus part of NCOA1. The fusion protein acts as a transcriptional activator. Rhabdomyosarcoma is the most common soft tissue carcinoma in childhood, representing 5-8% of all malignancies in children.
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~RORG_HUMAN RORG_HUMAN~~]] Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock. [[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.<ref>PMID:9427757</ref> <ref>PMID:7481822</ref> <ref>PMID:9223431</ref> <ref>PMID:9296499</ref> <ref>PMID:9223281</ref> <ref>PMID:10449719</ref> <ref>PMID:12954634</ref>	+	[https://www.uniprot.org/uniprot/G1RH57_NOMLE G1RH57_NOMLE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 29:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Histone acetyltransferase]]~~	+	[[Category: Homo sapiens]]
-	~~[[Category: Human]]~~	+
-	~~[[Category: Hylobates concolor leucogenys~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Adachi, T]]	+	[[Category: Adachi T]]
-	[[Category: Doi, S]]	+	[[Category: Doi S]]
-	[[Category: Murase, K]]	+	[[Category: Murase K]]
-	[[Category: Noguchi, M]]	+	[[Category: Noguchi M]]
-	[[Category: Nomura, A]]	+	[[Category: Nomura A]]
-	[[Category: Yamaguchi, K]]	+	[[Category: Yamaguchi K]]
-	~~[[Category: Binary complex]]~~	+
-	~~[[Category: Inhibitor]]~~	+
-	~~[[Category: Nuclear receptor]]~~	+
-	~~[[Category: Transcription-inhibitor complex~~]]	+

OCA at 10:30, 17 June 2020

OCA — Wed, 17 Jun 2020 10:30:52 GMT

←Older revision		Revision as of 10:30, 17 June 2020
Line 1:		Line 1:

	==Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain.==		==Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain.==
-	<StructureSection load='5x8w' size='340' side='right' caption='[[5x8w]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='5x8w' size='340' side='right'caption='[[5x8w]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5x8w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8W OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5X8W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5x8w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Hylobates_concolor_leucogenys Hylobates concolor leucogenys]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8W OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5X8W FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5x8u\|5x8u]], [[5x8s\|5x8s]], [[5x8x\|5x8x]], [[5x8q\|5x8q]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5x8u\|5x8u]], [[5x8s\|5x8s]], [[5x8x\|5x8x]], [[5x8q\|5x8q]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RORC, NR1F3, RORG, RZRG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=61853 Hylobates concolor leucogenys]), NCOA1, BHLHE74, SRC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5x8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8w OCA], [http://pdbe.org/5x8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x8w RCSB], [http://www.ebi.ac.uk/pdbsum/5x8w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8w ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5x8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8w OCA], [http://pdbe.org/5x8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x8w RCSB], [http://www.ebi.ac.uk/pdbsum/5x8w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8w ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
	[[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Note=A chromosomal aberration involving NCOA1 is a cause of rhabdomyosarcoma. Translocation t(2;2)(q35;p23) with PAX3 generates the NCOA1-PAX3 oncogene consisting of the N-terminus part of PAX3 and the C-terminus part of NCOA1. The fusion protein acts as a transcriptional activator. Rhabdomyosarcoma is the most common soft tissue carcinoma in childhood, representing 5-8% of all malignancies in children.		[[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Note=A chromosomal aberration involving NCOA1 is a cause of rhabdomyosarcoma. Translocation t(2;2)(q35;p23) with PAX3 generates the NCOA1-PAX3 oncogene consisting of the N-terminus part of PAX3 and the C-terminus part of NCOA1. The fusion protein acts as a transcriptional activator. Rhabdomyosarcoma is the most common soft tissue carcinoma in childhood, representing 5-8% of all malignancies in children.
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.<ref>PMID:9427757</ref> <ref>PMID:7481822</ref> <ref>PMID:9223431</ref> <ref>PMID:9296499</ref> <ref>PMID:9223281</ref> <ref>PMID:10449719</ref> <ref>PMID:12954634</ref>	+	[[http://www.uniprot.org/uniprot/RORG_HUMAN RORG_HUMAN]] Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock. [[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.<ref>PMID:9427757</ref> <ref>PMID:7481822</ref> <ref>PMID:9223431</ref> <ref>PMID:9296499</ref> <ref>PMID:9223281</ref> <ref>PMID:10449719</ref> <ref>PMID:12954634</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 22:
	</div>		</div>
	<div class="pdbe-citations 5x8w" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5x8w" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Nuclear receptor corepressor\|Nuclear receptor corepressor]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Histone acetyltransferase]]		[[Category: Histone acetyltransferase]]
		+	[[Category: Human]]
		+	[[Category: Hylobates concolor leucogenys]]
		+	[[Category: Large Structures]]
	[[Category: Adachi, T]]		[[Category: Adachi, T]]
	[[Category: Doi, S]]		[[Category: Doi, S]]

OCA at 09:27, 3 August 2017

OCA — Thu, 03 Aug 2017 09:27:48 GMT

←Older revision		Revision as of 09:27, 3 August 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5x8w is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain.==
		+	<StructureSection load='5x8w' size='340' side='right' caption='[[5x8w]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5x8w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X8W FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5x8u\|5x8u]], [[5x8s\|5x8s]], [[5x8x\|5x8x]], [[5x8q\|5x8q]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8w OCA], [http://pdbe.org/5x8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x8w RCSB], [http://www.ebi.ac.uk/pdbsum/5x8w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8w ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Note=A chromosomal aberration involving NCOA1 is a cause of rhabdomyosarcoma. Translocation t(2;2)(q35;p23) with PAX3 generates the NCOA1-PAX3 oncogene consisting of the N-terminus part of PAX3 and the C-terminus part of NCOA1. The fusion protein acts as a transcriptional activator. Rhabdomyosarcoma is the most common soft tissue carcinoma in childhood, representing 5-8% of all malignancies in children.
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.<ref>PMID:9427757</ref> <ref>PMID:7481822</ref> <ref>PMID:9223431</ref> <ref>PMID:9296499</ref> <ref>PMID:9223281</ref> <ref>PMID:10449719</ref> <ref>PMID:12954634</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Retinoid-related orphan receptor gamma (RORgamma) directly controls the differentiation of Th17 cell and the production of interleukin-17, which plays an integral role in autoimmune diseases. To obtain insight into RORgamma, we have determined the first crystal structure of a ternary complex containing RORgamma ligand-binding domain (LBD) bound with a novel synthetic inhibitor and a repressor peptide, 22-mer peptide from silencing mediator of retinoic acid and thyroid hormone receptor (SMRT). Comparison of a binary complex of nonliganded (apo) RORgamma-LBD with a nuclear receptor co-activator (NCoA-1) peptide has shown that our inhibitor displays a unique mechanism different from those caused by natural inhibitor, ursolic acid (UA). The compound unprecedentedly induces indirect disruption of a hydrogen bond between His479 on helix 11 (H11) and Tyr502 on H12, which is crucial for active conformation. This crystallographic study will allow us to develop novel synthetic compounds for autoimmune disease therapy.

-	~~Authors: Noguchi~~, M., ~~Nomura~~, A., Murase, K., Doi, S., Yamaguchi, K., ~~Adachi~~, T.	+	Ternary complex of human RORgamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment.,Noguchi M, Nomura A, Murase K, Doi S, Yamaguchi K, Hirata K, Shiozaki M, Hirashima S, Kotoku M, Yamaguchi T, Katsuda Y, Steensma R, Li X, Tao H, Tse B, Fenn M, Babine R, Bradley E, Crowe P, Thacher S, Adachi T, Kamada M Genes Cells. 2017 Jun;22(6):535-551. doi: 10.1111/gtc.12494. Epub 2017 May 11. PMID:28493531<ref>PMID:28493531</ref>

-	~~Description: Crystal Structure~~ of the ~~mutant Human ROR gamma Ligand Binding Domain~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5x8w" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Histone acetyltransferase]]
		+	[[Category: Adachi, T]]
	[[Category: Doi, S]]		[[Category: Doi, S]]
-	[[Category: Nomura, A]]
	[[Category: Murase, K]]		[[Category: Murase, K]]
-	[[Category: Adachi, T]]
	[[Category: Noguchi, M]]		[[Category: Noguchi, M]]
		+	[[Category: Nomura, A]]
	[[Category: Yamaguchi, K]]		[[Category: Yamaguchi, K]]
		+	[[Category: Binary complex]]
		+	[[Category: Inhibitor]]
		+	[[Category: Nuclear receptor]]
		+	[[Category: Transcription-inhibitor complex]]

OCA at 12:22, 5 April 2017

OCA — Wed, 05 Apr 2017 12:22:07 GMT

←Older revision		Revision as of 12:22, 5 April 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5x8w is ON HOLD	+	The entry 5x8w is ON HOLD until Paper Publication

	Authors: Noguchi, M., Nomura, A., Murase, K., Doi, S., Yamaguchi, K., Adachi, T.		Authors: Noguchi, M., Nomura, A., Murase, K., Doi, S., Yamaguchi, K., Adachi, T.

OCA at 20:19, 15 March 2017

OCA — Wed, 15 Mar 2017 20:19:05 GMT

←Older revision		Revision as of 20:19, 15 March 2017
Line 3:		Line 3:
	The entry 5x8w is ON HOLD		The entry 5x8w is ON HOLD

-	Authors: ~~Masato~~ Noguchi, ~~Akihiro~~ Nomura, ~~Ken~~ Murase, ~~Satoki~~ Doi, ~~Keishi~~ Yamaguchi, ~~Tsuyoshi~~ Adachi	+	Authors: Noguchi, M., Nomura, A., Murase, K., Doi, S., Yamaguchi, K., Adachi, T.

	Description: Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain.		Description: Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain.
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Masato Noguchi~~, ~~Akihiro~~ Nomura, ~~Ken~~ Murase, ~~Satoki Doi~~, ~~Keishi~~ Yamaguchi, ~~Tsuyoshi Adachi~~]]	+	[[Category: Doi, S]]
		+	[[Category: Nomura, A]]
		+	[[Category: Murase, K]]
		+	[[Category: Adachi, T]]
		+	[[Category: Noguchi, M]]
		+	[[Category: Yamaguchi, K]]

OCA: Protected "5x8w" [edit=sysop:move=sysop]

OCA — Thu, 09 Mar 2017 15:55:09 GMT

Protected "5x8w" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:55, 9 March 2017

OCA: New page: '''Unreleased structure''' The entry 5x8w is ON HOLD Authors: Masato Noguchi, Akihiro Nomura, Ken Murase, Satoki Doi, Keishi Yamaguchi, Tsuyoshi Adachi Description: Crystal Structure o...

OCA — Thu, 09 Mar 2017 15:55:08 GMT

New page: '''Unreleased structure''' The entry 5x8w is ON HOLD Authors: Masato Noguchi, Akihiro Nomura, Ken Murase, Satoki Doi, Keishi Yamaguchi, Tsuyoshi Adachi Description: Crystal Structure o...

New page

'''Unreleased structure'''

The entry 5x8w is ON HOLD

Authors: Masato Noguchi, Akihiro Nomura, Ken Murase, Satoki Doi, Keishi Yamaguchi, Tsuyoshi Adachi

Description: Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain.
[[Category: Unreleased Structures]]
[[Category: Masato Noguchi, Akihiro Nomura, Ken Murase, Satoki Doi, Keishi Yamaguchi, Tsuyoshi Adachi]]