5xeu - Revision history

OCA at 08:00, 22 November 2023

OCA — Wed, 22 Nov 2023 08:00:57 GMT

←Older revision		Revision as of 08:00, 22 November 2023
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	<StructureSection load='5xeu' size='340' side='right'caption='[[5xeu]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='5xeu' size='340' side='right'caption='[[5xeu]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xeu]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5XEU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xeu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XEU FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5xeu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xeu OCA], [~~http~~://pdbe.org/5xeu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xeu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xeu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xeu ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xeu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xeu OCA], [https://pdbe.org/5xeu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xeu RCSB], [https://www.ebi.ac.uk/pdbsum/5xeu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xeu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/H9L4J8_SALTM H9L4J8_SALTM]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Gao, Z Q~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-	[[Category: ~~Lin, Q P~~]]	+	[[Category: Gao ZQ]]
-	[[Category: ~~Zhang, H~~]]	+	[[Category: Lin QP]]
-	[[Category: ~~Cytosolic protein]]~~	+	[[Category: Zhang H]]
-	~~[[Category: Hexameric~~]]	+

OCA at 06:47, 14 October 2020

OCA — Wed, 14 Oct 2020 06:47:49 GMT

←Older revision		Revision as of 06:47, 14 October 2020
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	==crystal structure of Hcp2 from Salmonella typhimurium==		==crystal structure of Hcp2 from Salmonella typhimurium==
-	<StructureSection load='5xeu' size='340' side='right' caption='[[5xeu]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='5xeu' size='340' side='right'caption='[[5xeu]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xeu]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEU OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XEU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xeu]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XEU FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xeu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xeu OCA], [http://pdbe.org/5xeu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xeu RCSB], [http://www.ebi.ac.uk/pdbsum/5xeu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xeu ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xeu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xeu OCA], [http://pdbe.org/5xeu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xeu RCSB], [http://www.ebi.ac.uk/pdbsum/5xeu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xeu ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Gao, Z Q]]		[[Category: Gao, Z Q]]
	[[Category: Lin, Q P]]		[[Category: Lin, Q P]]

OCA at 06:03, 17 August 2017

OCA — Thu, 17 Aug 2017 06:03:39 GMT

←Older revision		Revision as of 06:03, 17 August 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5xeu is ~~ON HOLD until Paper~~ Publication	+	==crystal structure of Hcp2 from Salmonella typhimurium==
		+	<StructureSection load='5xeu' size='340' side='right' caption='[[5xeu]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5xeu]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XEU FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xeu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xeu OCA], [http://pdbe.org/5xeu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xeu RCSB], [http://www.ebi.ac.uk/pdbsum/5xeu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xeu ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	STM0279 is a putative cytoplasmic protein from Salmonella typhimurium and was recently renamed haemolysin co-regulated protein 2 (Hcp2), with the neighbouring STM0276 being Hcp1. Both of them are encoded by the type VI secretion system (T6SS) of the Salmonella pathogenicity island 6 (SPI-6) locus and have high sequence identity. The Hcp proteins may function as a vital component of the T6SS nanotube and as a transporter and chaperone of diverse effectors from the bacterial T6SS. In this study, the crystal structure and the oligomeric state in solution of Hcp2 from S. typhimurium (StHcp2) were investigated. The crystal structure refined to 3.0 A resolution showed that the protein is composed of a beta-barrel domain with extended loops and can form hexameric rings as observed in known Hcp homologues. Mutation of the extended loop was found to partly destabilize the hexameric conformation into monomers or cause the production of inclusion bodies, suggesting it has an important role in hexameric ring formation.

-	~~Authors: Lin, Q.P~~., Gao, Z~~.Q.~~, Zhang, H.	+	Crystal structure of the putative cytoplasmic protein STM0279 (Hcp2) from Salmonella typhimurium.,Lin QP, Gao ZQ, Geng Z, Zhang H, Dong YH Acta Crystallogr F Struct Biol Commun. 2017 Aug 1;73(Pt 8):463-468. doi:, 10.1107/S2053230X17010512. Epub 2017 Jul 26. PMID:28777089<ref>PMID:28777089</ref>

-	~~Description: crystal structure~~ of ~~Hcp2 from Salmonella typhimurium~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5xeu" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Gao, Z Q]]
		+	[[Category: Lin, Q P]]
	[[Category: Zhang, H]]		[[Category: Zhang, H]]
-	[[Category: ~~Gao, Z.Q~~]]	+	[[Category: Cytosolic protein]]
-	[[Category: ~~Lin, Q.P~~]]	+	[[Category: Hexameric]]

OCA at 12:06, 19 April 2017

OCA — Wed, 19 Apr 2017 12:06:26 GMT

←Older revision		Revision as of 12:06, 19 April 2017
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5xeu is ON HOLD	+	The entry 5xeu is ON HOLD until Paper Publication

	Authors: Lin, Q.P., Gao, Z.Q., Zhang, H.		Authors: Lin, Q.P., Gao, Z.Q., Zhang, H.

OCA: Protected "5xeu" [edit=sysop:move=sysop]

OCA — Wed, 12 Apr 2017 10:42:26 GMT

Protected "5xeu" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:42, 12 April 2017

OCA: New page: '''Unreleased structure''' The entry 5xeu is ON HOLD Authors: Lin, Q.P., Gao, Z.Q., Zhang, H. Description: crystal structure of Hcp2 from Salmonella typhimurium [[Category: Unreleased ...

OCA — Wed, 12 Apr 2017 10:42:25 GMT

New page: '''Unreleased structure''' The entry 5xeu is ON HOLD Authors: Lin, Q.P., Gao, Z.Q., Zhang, H. Description: crystal structure of Hcp2 from Salmonella typhimurium [[Category: Unreleased ...

New page

'''Unreleased structure'''

The entry 5xeu is ON HOLD

Authors: Lin, Q.P., Gao, Z.Q., Zhang, H.

Description: crystal structure of Hcp2 from Salmonella typhimurium
[[Category: Unreleased Structures]]
[[Category: Zhang, H]]
[[Category: Gao, Z.Q]]
[[Category: Lin, Q.P]]