5xhq - Revision history

OCA at 08:02, 22 November 2023

OCA — Wed, 22 Nov 2023 08:02:24 GMT

←Older revision		Revision as of 08:02, 22 November 2023
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	==Apolipoprotein N-acyl Transferase==		==Apolipoprotein N-acyl Transferase==
-	<StructureSection load='5xhq' size='340' side='right' caption='[[5xhq]], [[Resolution\|resolution]] 2.59Å' scene=''>	+	<StructureSection load='5xhq' size='340' side='right'caption='[[5xhq]], [[Resolution\|resolution]] 2.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xhq]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XHQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XHQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xhq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XHQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HTG:HEPTYL+1-THIOHEXOPYRANOSIDE'>HTG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.587Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lnt, cutE, b0657, JW0654 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HTG:HEPTYL+1-THIOHEXOPYRANOSIDE'>HTG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xhq OCA], [~~http~~://pdbe.org/5xhq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xhq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xhq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xhq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xhq OCA], [https://pdbe.org/5xhq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xhq RCSB], [https://www.ebi.ac.uk/pdbsum/5xhq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xhq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/LNT_ECOLI LNT_ECOLI]] Transfers the fatty acyl group on membrane lipoproteins.	+	[https://www.uniprot.org/uniprot/LNT_ECOLI LNT_ECOLI] Transfers the fatty acyl group on membrane lipoproteins.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
-	[[Category: Fei, S]]	+	[[Category: Large Structures]]
-	[[Category: Guangyuan, L]]	+	[[Category: Fei S]]
-	[[Category: Yingzhi, X]]	+	[[Category: Guangyuan L]]
-	[[Category: Yong, X]]	+	[[Category: Yingzhi X]]
-	~~[[Category: Nitrilase post-lipidation lipoprotein]]~~	+	[[Category: Yong X]]
-	~~[[Category: Transferase~~]]	+

OCA at 06:06, 1 November 2017

OCA — Wed, 01 Nov 2017 06:06:27 GMT

←Older revision		Revision as of 06:06, 1 November 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5xhq is ~~ON HOLD~~	+	==Apolipoprotein N-acyl Transferase==
		+	<StructureSection load='5xhq' size='340' side='right' caption='[[5xhq]], [[Resolution\|resolution]] 2.59Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5xhq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XHQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XHQ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HTG:HEPTYL+1-THIOHEXOPYRANOSIDE'>HTG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lnt, cutE, b0657, JW0654 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xhq OCA], [http://pdbe.org/5xhq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xhq RCSB], [http://www.ebi.ac.uk/pdbsum/5xhq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xhq ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LNT_ECOLI LNT_ECOLI]] Transfers the fatty acyl group on membrane lipoproteins.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In Gram-negative bacteria, lipid modification of proteins is catalysed in a three-step pathway. Apolipoprotein N-acyl transferase (Lnt) catalyses the third step in this pathway, whereby it transfers an acyl chain from a phospholipid to the amine group of the N-terminal cysteine residue of the apolipoprotein. Here, we report the 2.6-A crystal structure of Escherichia coli Lnt. This enzyme contains an exo-membrane nitrilase domain fused to a transmembrane (TM) domain. The TM domain of Lnt contains eight TM helices which form a membrane-embedded cavity with a lateral opening and a periplasmic exit. The nitrilase domain is located on the periplasmic side of the membrane, with its catalytic cavity connected to the periplasmic exit of the TM domain. An amphipathic lid loop from the nitrilase domain interacts with the periplasmic lipid leaflet, forming an interfacial entrance from the lipid bilayer to the catalytic centre for both the lipid donor and acceptor substrates.

-	~~Authors~~:	+	Crystal structure of E. coli apolipoprotein N-acyl transferase.,Lu G, Xu Y, Zhang K, Xiong Y, Li H, Cui L, Wang X, Lou J, Zhai Y, Sun F, Zhang XC Nat Commun. 2017 Jul 4;8:15948. doi: 10.1038/ncomms15948. PMID:28885614<ref>PMID:28885614</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5xhq" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Ecoli]]
		+	[[Category: Fei, S]]
		+	[[Category: Guangyuan, L]]
		+	[[Category: Yingzhi, X]]
		+	[[Category: Yong, X]]
		+	[[Category: Nitrilase post-lipidation lipoprotein]]
		+	[[Category: Transferase]]

OCA: Protected "5xhq" [edit=sysop:move=sysop]

OCA — Thu, 04 May 2017 12:12:53 GMT

Protected "5xhq" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:12, 4 May 2017

OCA: New page: '''Unreleased structure''' The entry 5xhq is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 04 May 2017 12:12:52 GMT

New page: '''Unreleased structure''' The entry 5xhq is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5xhq is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]