5xjx - Revision history

OCA at 08:04, 22 November 2023

OCA — Wed, 22 Nov 2023 08:04:56 GMT

←Older revision		Revision as of 08:04, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='5xjx' size='340' side='right'caption='[[5xjx]], [[Resolution\|resolution]] 3.06Å' scene=''>		<StructureSection load='5xjx' size='340' side='right'caption='[[5xjx]], [[Resolution\|resolution]] 3.06Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xjx]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XJX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xjx]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XJX FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>TMM, RLP17, At1g80080, F18B13.16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id~~=3702 ARATH]), ERL1, At5g62230, MMI9.14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.055Å</td></tr>
-	~~<tr id='activity'><td class~~="~~sblockLbl~~">~~<b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non~~-~~specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase]~~, ~~with EC number~~ [~~http://www~~.~~brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span>~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xjx OCA], [https://pdbe.org/5xjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xjx RCSB], [https://www.ebi.ac.uk/pdbsum/5xjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xjx ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xjx OCA], [~~http~~://pdbe.org/5xjx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xjx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xjx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xjx ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/TMM_ARATH TMM_ARATH]] Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC) (PubMed:11090210, PubMed:12040198, PubMed:18979118). Positively regulates CAPRICE (CPC) expression in differentiating stomaless-forming cell files (PubMed:19513241). Forms constitutive complexes with ERECTA and ERL1 involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146). Modulates the activity of the ligand-receptor pairs EPF2-ERECTA and EPF1-ERL1 in stomatal development (PubMed:16002616, PubMed:22241782). Functions in a combinatorial specific manner with the ERECTA-family (ERf) receptor kinases in the regulation of the immune response (PubMed:27446127).<ref>PMID:11090210</ref> <ref>PMID:12040198</ref> <ref>PMID:16002616</ref> <ref>PMID:18979118</ref> <ref>PMID:19513241</ref> <ref>PMID:22241782</ref> <ref>PMID:27446127</ref> <ref>PMID:28536146</ref> [[http://www.uniprot.org/uniprot/ERL1_ARATH ERL1_ARATH]] Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ER and ERL2. Redundantly involved with ER in procambial development regulation. Forms a functional ligand-receptor pair with EPF1 (AC Q8S8I4) (PubMed:22241782). Forms a constitutive complex with TMM involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146).<ref>PMID:14985254</ref> <ref>PMID:16002616</ref> <ref>PMID:17652352</ref> <ref>PMID:22241782</ref> <ref>PMID:23881395</ref> <ref>PMID:28536146</ref>	+	[https://www.uniprot.org/uniprot/TMM_ARATH TMM_ARATH] Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC) (PubMed:11090210, PubMed:12040198, PubMed:18979118). Positively regulates CAPRICE (CPC) expression in differentiating stomaless-forming cell files (PubMed:19513241). Forms constitutive complexes with ERECTA and ERL1 involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146). Modulates the activity of the ligand-receptor pairs EPF2-ERECTA and EPF1-ERL1 in stomatal development (PubMed:16002616, PubMed:22241782). Functions in a combinatorial specific manner with the ERECTA-family (ERf) receptor kinases in the regulation of the immune response (PubMed:27446127).<ref>PMID:11090210</ref> <ref>PMID:12040198</ref> <ref>PMID:16002616</ref> <ref>PMID:18979118</ref> <ref>PMID:19513241</ref> <ref>PMID:22241782</ref> <ref>PMID:27446127</ref> <ref>PMID:28536146</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Non-specific serine/threonine protein kinase]]~~	+	[[Category: Chai J]]
-	[[Category: Chai, J]]	+	[[Category: Chang J]]
-	[[Category: Chang, J]]	+	[[Category: Han Z]]
-	[[Category: Han, Z]]	+	[[Category: Li E]]
-	[[Category: Li, E]]	+	[[Category: Lin G]]
-	[[Category: Lin, G]]	+	[[Category: Liu W]]
-	[[Category: Liu, W]]	+	[[Category: Qi Y]]
-	[[Category: Qi, Y]]	+	[[Category: Yang X]]
-	[[Category: Yang, X]]	+	[[Category: Zhang L]]
-	[[Category: Zhang, L]]	+
-	~~[[Category: Pre-formed complexe]]~~	+
-	~~[[Category: Receptor like kinase]]~~	+
-	~~[[Category: Receptor like protein]]~~	+
-	~~[[Category: Transferase-membrane protein complex~~]]	+

OCA at 09:44, 4 December 2019

OCA — Wed, 04 Dec 2019 09:44:02 GMT

←Older revision		Revision as of 09:44, 4 December 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5xjx is ~~ON HOLD~~	+	==Pre-formed plant receptor ERL1-TMM complex==
		+	<StructureSection load='5xjx' size='340' side='right'caption='[[5xjx]], [[Resolution\|resolution]] 3.06Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5xjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XJX FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TMM, RLP17, At1g80080, F18B13.16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH]), ERL1, At5g62230, MMI9.14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xjx OCA], [http://pdbe.org/5xjx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xjx RCSB], [http://www.ebi.ac.uk/pdbsum/5xjx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xjx ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TMM_ARATH TMM_ARATH]] Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC) (PubMed:11090210, PubMed:12040198, PubMed:18979118). Positively regulates CAPRICE (CPC) expression in differentiating stomaless-forming cell files (PubMed:19513241). Forms constitutive complexes with ERECTA and ERL1 involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146). Modulates the activity of the ligand-receptor pairs EPF2-ERECTA and EPF1-ERL1 in stomatal development (PubMed:16002616, PubMed:22241782). Functions in a combinatorial specific manner with the ERECTA-family (ERf) receptor kinases in the regulation of the immune response (PubMed:27446127).<ref>PMID:11090210</ref> <ref>PMID:12040198</ref> <ref>PMID:16002616</ref> <ref>PMID:18979118</ref> <ref>PMID:19513241</ref> <ref>PMID:22241782</ref> <ref>PMID:27446127</ref> <ref>PMID:28536146</ref> [[http://www.uniprot.org/uniprot/ERL1_ARATH ERL1_ARATH]] Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ER and ERL2. Redundantly involved with ER in procambial development regulation. Forms a functional ligand-receptor pair with EPF1 (AC Q8S8I4) (PubMed:22241782). Forms a constitutive complex with TMM involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146).<ref>PMID:14985254</ref> <ref>PMID:16002616</ref> <ref>PMID:17652352</ref> <ref>PMID:22241782</ref> <ref>PMID:23881395</ref> <ref>PMID:28536146</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Stomata are microscopic openings that allow for the exchange of gases between plants and the environment. In Arabidopsis, stomatal patterning is specified by the ERECTA family (ERf) receptor kinases (RKs), the receptor-like protein (RLP) TOO MANY MOUTHS (TMM), and EPIDERMAL PATTERNING FACTOR (EPF) peptides. Here we show that TMM and ER or ER-LIKE1 (ERL1) form constitutive complexes, which recognize EPF1 and EPF2, but the single ERfs do not. TMM interaction with ERL1 creates a binding pocket for recognition of EPF1 and EPF2, indicating that the constitutive TMM-ERf complexes function as the receptors of EPF1 and EPF2. EPFL9 competes with EPF1 and EPF2 for binding to the ERf-TMM complex. EPFL4 and EPFL6, however, are recognized by the single ERfs without the requirement of TMM. In contrast to EPF1,2, the interaction of EPFL4,6 with an ERf is greatly reduced in the presence of TMM. Taken together, our data demonstrate that TMM dictates the specificity of ERfs for the perception of different EPFs, thus functioning as a specificity switch for the regulation of the activities of ERfs.

-	~~Authors: Chai, J~~., Lin, G., Zhang, L., Han, Z., Yang, X., Liu, W., Qi, Y., ~~Chang~~, J., ~~Li, E~~.	+	A receptor-like protein acts as a specificity switch for the regulation of stomatal development.,Lin G, Zhang L, Han Z, Yang X, Liu W, Li E, Chang J, Qi Y, Shpak ED, Chai J Genes Dev. 2017 May 1;31(9):927-938. doi: 10.1101/gad.297580.117. Epub 2017 May, 23. PMID:28536146<ref>PMID:28536146</ref>

-	~~Description: Pre~~-~~formed plant recetor ERL1~~-~~TMM complexe~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
-	[[Category: ~~Yang, X~~]]	+	<div class="pdbe-citations 5xjx" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Lin~~, G]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Arath]]
		+	[[Category: Large Structures]]
		+	[[Category: Non-specific serine/threonine protein kinase]]
		+	[[Category: Chai, J]]
	[[Category: Chang, J]]		[[Category: Chang, J]]
-	[[Category: Liu, W]]
-	[[Category: Zhang, L]]
	[[Category: Han, Z]]		[[Category: Han, Z]]
-	[[Category: Chai, J]]
-	[[Category: Qi, Y]]
	[[Category: Li, E]]		[[Category: Li, E]]
		+	[[Category: Lin, G]]
		+	[[Category: Liu, W]]
		+	[[Category: Qi, Y]]
		+	[[Category: Yang, X]]
		+	[[Category: Zhang, L]]
		+	[[Category: Pre-formed complexe]]
		+	[[Category: Receptor like kinase]]
		+	[[Category: Receptor like protein]]
		+	[[Category: Transferase-membrane protein complex]]

OCA at 15:31, 27 September 2017

OCA — Wed, 27 Sep 2017 15:31:39 GMT

←Older revision		Revision as of 15:31, 27 September 2017
Line 8:		Line 8:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Yang, X]]		[[Category: Yang, X]]
		+	[[Category: Lin, G]]
		+	[[Category: Chang, J]]
	[[Category: Liu, W]]		[[Category: Liu, W]]
	[[Category: Zhang, L]]		[[Category: Zhang, L]]
	[[Category: Han, Z]]		[[Category: Han, Z]]
	[[Category: Chai, J]]		[[Category: Chai, J]]
-	[[Category: Lin, G]]
	[[Category: Qi, Y]]		[[Category: Qi, Y]]
	[[Category: Li, E]]		[[Category: Li, E]]
-	[[Category: Chang, J]]

OCA at 12:32, 24 May 2017

OCA — Wed, 24 May 2017 12:32:38 GMT

←Older revision		Revision as of 12:32, 24 May 2017
Line 3:		Line 3:
	The entry 5xjx is ON HOLD		The entry 5xjx is ON HOLD

-	Authors: ~~Jijie~~ Chai, ~~Guangzhong~~ Lin, ~~Liang~~ Zhang, ~~Zhifu~~ Han, ~~Xinru~~ Yang, ~~Weijia~~ Liu, ~~Yijun~~ Qi, ~~Junbiao~~ Chang, ~~Ertong~~ Li	+	Authors: Chai, J., Lin, G., Zhang, L., Han, Z., Yang, X., Liu, W., Qi, Y., Chang, J., Li, E.

-	Description: ~~pre~~-formed plant recetor ERL1-TMM complexe	+	Description: Pre-formed plant recetor ERL1-TMM complexe
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Jijie Chai~~, ~~Guangzhong Lin~~, ~~Liang~~ Zhang, ~~Zhifu~~ Han, ~~Xinru Yang~~, ~~Weijia Liu~~, ~~Yijun~~ Qi, ~~Junbiao~~ Chang, ~~Ertong Li~~]]	+	[[Category: Yang, X]]
		+	[[Category: Liu, W]]
		+	[[Category: Zhang, L]]
		+	[[Category: Han, Z]]
		+	[[Category: Chai, J]]
		+	[[Category: Lin, G]]
		+	[[Category: Qi, Y]]
		+	[[Category: Li, E]]
		+	[[Category: Chang, J]]

OCA: Protected "5xjx" [edit=sysop:move=sysop]

OCA — Wed, 10 May 2017 12:02:39 GMT

Protected "5xjx" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:02, 10 May 2017

OCA: New page: '''Unreleased structure''' The entry 5xjx is ON HOLD Authors: Jijie Chai, Guangzhong Lin, Liang Zhang, Zhifu Han, Xinru Yang, Weijia Liu, Yijun Qi, Junbiao Chang, Ertong Li Description...

OCA — Wed, 10 May 2017 12:02:38 GMT

New page: '''Unreleased structure''' The entry 5xjx is ON HOLD Authors: Jijie Chai, Guangzhong Lin, Liang Zhang, Zhifu Han, Xinru Yang, Weijia Liu, Yijun Qi, Junbiao Chang, Ertong Li Description...

New page

'''Unreleased structure'''

The entry 5xjx is ON HOLD

Authors: Jijie Chai, Guangzhong Lin, Liang Zhang, Zhifu Han, Xinru Yang, Weijia Liu, Yijun Qi, Junbiao Chang, Ertong Li

Description: pre-formed plant recetor ERL1-TMM complexe
[[Category: Unreleased Structures]]
[[Category: Jijie Chai, Guangzhong Lin, Liang Zhang, Zhifu Han, Xinru Yang, Weijia Liu, Yijun Qi, Junbiao Chang, Ertong Li]]