5xv1 - Revision history

OCA at 08:14, 22 November 2023

OCA — Wed, 22 Nov 2023 08:14:32 GMT

←Older revision		Revision as of 08:14, 22 November 2023
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	<StructureSection load='5xv1' size='340' side='right'caption='[[5xv1]], [[Resolution\|resolution]] 2.51Å' scene=''>		<StructureSection load='5xv1' size='340' side='right'caption='[[5xv1]], [[Resolution\|resolution]] 2.51Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xv1]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XV1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XV1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xv1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XV1 FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~ATG13~~, ~~KIAA0652 (~~[~~http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN~~]~~), ATG101, C12orf44, PP894 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=9606 HUMAN])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.508Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xv1 OCA], [~~http~~://pdbe.org/5xv1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xv1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xv1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xv1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xv1 OCA], [https://pdbe.org/5xv1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xv1 RCSB], [https://www.ebi.ac.uk/pdbsum/5xv1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xv1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ATG13_HUMAN ATG13_HUMAN]] Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.<ref>PMID:19287211</ref> <ref>PMID:19211835</ref> <ref>PMID:19225151</ref> <ref>PMID:21855797</ref> <ref>PMID:18936157</ref> <ref>PMID:21795849</ref> [[http://www.uniprot.org/uniprot/ATGA1_HUMAN ATGA1_HUMAN]] Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.<ref>PMID:19287211</ref> <ref>PMID:19597335</ref>	+	[https://www.uniprot.org/uniprot/ATG13_HUMAN ATG13_HUMAN] Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.<ref>PMID:19287211</ref> <ref>PMID:19211835</ref> <ref>PMID:19225151</ref> <ref>PMID:21855797</ref> <ref>PMID:18936157</ref> <ref>PMID:21795849</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kim, B W]]	+	[[Category: Kim B-W]]
-	[[Category: Song~~, H K]]~~	+	[[Category: Song HK]]
-	~~[[Category: Atg101]]~~	+
-	~~[[Category: Atg13]]~~	+
-	~~[[Category: Autophagy]]~~	+
-	~~[[Category: Horma]]~~	+
-	~~[[Category: Protein binding~~]]	+

OCA at 08:31, 24 July 2019

OCA — Wed, 24 Jul 2019 08:31:19 GMT

←Older revision		Revision as of 08:31, 24 July 2019
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	==Crystal structure of ATG101-ATG13HORMA==		==Crystal structure of ATG101-ATG13HORMA==
-	<StructureSection load='5xv1' size='340' side='right' caption='[[5xv1]], [[Resolution\|resolution]] 2.51Å' scene=''>	+	<StructureSection load='5xv1' size='340' side='right'caption='[[5xv1]], [[Resolution\|resolution]] 2.51Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xv1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XV1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xv1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XV1 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xv1 OCA], [http://pdbe.org/5xv1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xv1 RCSB], [http://www.ebi.ac.uk/pdbsum/5xv1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xv1 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ATG13, KIAA0652 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), ATG101, C12orf44, PP894 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xv1 OCA], [http://pdbe.org/5xv1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xv1 RCSB], [http://www.ebi.ac.uk/pdbsum/5xv1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xv1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Kim, B W]]		[[Category: Kim, B W]]
	[[Category: Song, H K]]		[[Category: Song, H K]]

OCA at 07:07, 4 July 2018

OCA — Wed, 04 Jul 2018 07:07:15 GMT

←Older revision		Revision as of 07:07, 4 July 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5xv1 ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of ATG101-ATG13HORMA==
-		+	<StructureSection load='5xv1' size='340' side='right' caption='[[5xv1]], [[Resolution\|resolution]] 2.51Å' scene=''>
-	~~Authors~~: ~~Kim~~, B.-W., ~~Song~~, H.K.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5xv1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XV1 FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure~~ of ~~ATG101~~-~~ATG13HORMA~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xv1 OCA], [http://pdbe.org/5xv1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xv1 RCSB], [http://www.ebi.ac.uk/pdbsum/5xv1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xv1 ProSAT]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[Category: Kim, B.-W]]	+	== Function ==
-	[[Category: Song, H.K]]	+	[[http://www.uniprot.org/uniprot/ATG13_HUMAN ATG13_HUMAN]] Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.<ref>PMID:19287211</ref> <ref>PMID:19211835</ref> <ref>PMID:19225151</ref> <ref>PMID:21855797</ref> <ref>PMID:18936157</ref> <ref>PMID:21795849</ref> [[http://www.uniprot.org/uniprot/ATGA1_HUMAN ATGA1_HUMAN]] Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.<ref>PMID:19287211</ref> <ref>PMID:19597335</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Kim, B W]]
		+	[[Category: Song, H K]]
		+	[[Category: Atg101]]
		+	[[Category: Atg13]]
		+	[[Category: Autophagy]]
		+	[[Category: Horma]]
		+	[[Category: Protein binding]]

OCA: Protected "5xv1" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 15:48:35 GMT

Protected "5xv1" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:48, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5xv1 is ON HOLD until Paper Publication Authors: Kim, B.-W., Song, H.K. Description: Crystal structure of ATG101-ATG13HORMA [[Category: Unreleased ...

OCA — Wed, 27 Sep 2017 15:48:34 GMT

New page: '''Unreleased structure''' The entry 5xv1 is ON HOLD until Paper Publication Authors: Kim, B.-W., Song, H.K. Description: Crystal structure of ATG101-ATG13HORMA [[Category: Unreleased ...

New page

'''Unreleased structure'''

The entry 5xv1 is ON HOLD until Paper Publication

Authors: Kim, B.-W., Song, H.K.

Description: Crystal structure of ATG101-ATG13HORMA
[[Category: Unreleased Structures]]
[[Category: Kim, B.-W]]
[[Category: Song, H.K]]