5xyh - Revision history

OCA at 08:17, 22 November 2023

OCA — Wed, 22 Nov 2023 08:17:28 GMT

←Older revision		Revision as of 08:17, 22 November 2023
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	<StructureSection load='5xyh' size='340' side='right'caption='[[5xyh]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='5xyh' size='340' side='right'caption='[[5xyh]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xyh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5XYH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xyh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_oryzae_pv._oryzae Xanthomonas oryzae pv. oryzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XYH FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>~~[http://en.wikipedia.org/wiki/Cellulose_1,4~~-~~beta-cellobiosidase_(non-reducing_end) Cellulose 1~~,~~4-beta-cellobiosidase (non-reducing end)~~]~~, with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.~~1.~~91 3.2.1.91] </span>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.864Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5xyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyh OCA], [~~http~~://pdbe.org/5xyh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5xyh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5xyh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyh OCA], [https://pdbe.org/5xyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xyh RCSB], [https://www.ebi.ac.uk/pdbsum/5xyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyh ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A384E106_XANOO A0A384E106_XANOO]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Haque, A S~~]]	+	[[Category: Xanthomonas oryzae pv. oryzae]]
-	[[Category: ~~Kumar, S~~]]	+	[[Category: Haque AS]]
-	[[Category: ~~Nathawat, R~~]]	+	[[Category: Kumar S]]
-	[[Category: ~~Sankaranaryanan,~~ R]]	+	[[Category: Nathawat R]]
-	[[Category: ~~Bacterial blight]]~~	+	[[Category: Sankaranaryanan R]]
-	~~[[Category: Cell-wall degrading enzyme]]~~	+
-	~~[[Category: Exoglucanase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Xoo~~]]	+

OCA at 07:01, 14 October 2020

OCA — Wed, 14 Oct 2020 07:01:21 GMT

←Older revision		Revision as of 07:01, 14 October 2020
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	==Crystal Structure of catalytic domain of 1,4-beta-Cellobiosidase (CbsA) from Xanthomonas oryzae pv. oryzae==		==Crystal Structure of catalytic domain of 1,4-beta-Cellobiosidase (CbsA) from Xanthomonas oryzae pv. oryzae==
-	<StructureSection load='5xyh' size='340' side='right' caption='[[5xyh]], [[Resolution\|resolution]] 1.86Å' scene=''>	+	<StructureSection load='5xyh' size='340' side='right'caption='[[5xyh]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5xyh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYH OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5XYH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5xyh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XYH FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5xyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyh OCA], [http://pdbe.org/5xyh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xyh RCSB], [http://www.ebi.ac.uk/pdbsum/5xyh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyh OCA], [http://pdbe.org/5xyh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xyh RCSB], [http://www.ebi.ac.uk/pdbsum/5xyh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyh ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Haque, A S]]		[[Category: Haque, A S]]
	[[Category: Kumar, S]]		[[Category: Kumar, S]]

OCA at 05:26, 16 May 2018

OCA — Wed, 16 May 2018 05:26:39 GMT

←Older revision		Revision as of 05:26, 16 May 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 5xyh is ~~ON HOLD until Paper~~ Publication	+	==Crystal Structure of catalytic domain of 1,4-beta-Cellobiosidase (CbsA) from Xanthomonas oryzae pv. oryzae==
		+	<StructureSection load='5xyh' size='340' side='right' caption='[[5xyh]], [[Resolution\|resolution]] 1.86Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5xyh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XYH FirstGlance]. <br>
		+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyh OCA], [http://pdbe.org/5xyh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xyh RCSB], [http://www.ebi.ac.uk/pdbsum/5xyh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyh ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Xanthomonas oryzae pv. oryzae (Xoo) causes bacterial blight, a serious disease of rice. Xoo secretes a repertoire of cell wall-degrading enzymes, including cellulases, xylanases and pectinases, to degrade various polysaccharide components of the rice cell wall. A secreted Xoo cellulase, CbsA, is not only a key virulence factor of Xoo, but is also a potent inducer of innate immune responses of rice. In this study, we solved the crystal structure of the catalytic domain of the CbsA protein to a resolution of 1.86 A. The core structure of CbsA shows a central distorted TIM barrel made up of eight beta strands with N- and C-terminal loops enclosing the active site, which is a characteristic structural feature of an exoglucanase. The aspartic acid at the 131st position of CbsA was predicted to be important for catalysis and was therefore mutated to alanine to study its role in the catalysis and biological functions of CbsA. Intriguingly, the D131A CbsA mutant protein displayed the enzymatic activity of a typical endoglucanase. D131A CbsA was as proficient as wild-type (Wt) CbsA in inducing rice immune responses, but was deficient in virulence-promoting activity. This indicates that the specific exoglucanase activity of the Wt CbsA protein is required for this protein to promote the growth of Xoo in rice.

-	~~Authors~~:	+	A mutation in an exoglucanase of Xanthomonas oryzae pv. oryzae, which confers an endo mode of activity, affects bacterial virulence, but not the induction of immune responses, in rice.,Tayi L, Kumar S, Nathawat R, Haque AS, Maku RV, Patel HK, Sankaranarayanan R, Sonti RV Mol Plant Pathol. 2018 Jun;19(6):1364-1376. doi: 10.1111/mpp.12620. Epub 2017 Dec, 26. PMID:28976110<ref>PMID:28976110</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5xyh" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Haque, A S]]
		+	[[Category: Kumar, S]]
		+	[[Category: Nathawat, R]]
		+	[[Category: Sankaranaryanan, R]]
		+	[[Category: Bacterial blight]]
		+	[[Category: Cell-wall degrading enzyme]]
		+	[[Category: Exoglucanase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Xoo]]

OCA: Protected "5xyh" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 15:55:06 GMT

Protected "5xyh" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:55, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5xyh is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Wed, 27 Sep 2017 15:55:05 GMT

New page: '''Unreleased structure''' The entry 5xyh is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5xyh is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]