5y1v - Revision history

OCA at 08:19, 22 November 2023

OCA — Wed, 22 Nov 2023 08:19:18 GMT

←Older revision		Revision as of 08:19, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='5y1v' size='340' side='right'caption='[[5y1v]], [[Resolution\|resolution]] 1.62Å' scene=''>		<StructureSection load='5y1v' size='340' side='right'caption='[[5y1v]], [[Resolution\|resolution]] 1.62Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5y1v]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5Y1V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5y1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_FcB1/Columbia Plasmodium falciparum FcB1/Columbia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y1V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8LO:(2R)-2-[(2,6-diethylphenyl)carbamoylamino]-4-methyl-N-oxidanyl-pentanamide'>8LO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.62Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5y1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1v OCA], [~~http~~://pdbe.org/5y1v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5y1v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5y1v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1v ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8LO:(2R)-2-[(2,6-diethylphenyl)carbamoylamino]-4-methyl-N-oxidanyl-pentanamide'>8LO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1v OCA], [https://pdbe.org/5y1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y1v RCSB], [https://www.ebi.ac.uk/pdbsum/5y1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>	+	[https://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>

	==See Also==		==See Also==
Line 17:		Line 18:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Addlagatta, A~~]]	+	[[Category: Plasmodium falciparum FcB1/Columbia]]
-	[[Category: ~~Marapaka,~~ A K]]	+	[[Category: Addlagatta A]]
-	[[Category: ~~Zhang, Y~~]]	+	[[Category: Marapaka AK]]
-	[[Category: ~~Hydrolase-hydrolase inhibitor complex]]~~	+	[[Category: Zhang Y]]
-	~~[[Category: M1-class aminopeptidase~~]]	+

OCA at 07:03, 14 October 2020

OCA — Wed, 14 Oct 2020 07:03:56 GMT

←Older revision		Revision as of 07:03, 14 October 2020
Line 1:		Line 1:

	==Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide==		==Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide==
-	<StructureSection load='5y1v' size='340' side='right' caption='[[5y1v]], [[Resolution\|resolution]] 1.62Å' scene=''>	+	<StructureSection load='5y1v' size='340' side='right'caption='[[5y1v]], [[Resolution\|resolution]] 1.62Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5y1v]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1V OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5Y1V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5y1v]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5Y1V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8LO:(2R)-2-[(2,6-diethylphenyl)carbamoylamino]-4-methyl-N-oxidanyl-pentanamide'>8LO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8LO:(2R)-2-[(2,6-diethylphenyl)carbamoylamino]-4-methyl-N-oxidanyl-pentanamide'>8LO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5y1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1v OCA], [http://pdbe.org/5y1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y1v RCSB], [http://www.ebi.ac.uk/pdbsum/5y1v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5y1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1v OCA], [http://pdbe.org/5y1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y1v RCSB], [http://www.ebi.ac.uk/pdbsum/5y1v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>		[[http://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>
		+
		+	==See Also==
		+	*[[Aminopeptidase 3D structures\|Aminopeptidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Addlagatta, A]]		[[Category: Addlagatta, A]]
	[[Category: Marapaka, A K]]		[[Category: Marapaka, A K]]

OCA at 18:38, 1 August 2018

OCA — Wed, 01 Aug 2018 18:38:15 GMT

←Older revision		Revision as of 18:38, 1 August 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 5y1v is ON HOLD until Paper Publication~~	+	==Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide==
-		+	<StructureSection load='5y1v' size='340' side='right' caption='[[5y1v]], [[Resolution\|resolution]] 1.62Å' scene=''>
-	~~Authors: Marapaka, A.K., Zhang, Y., Addlagatta, A.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5y1v]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y1V FirstGlance]. <br>
-	~~Description:~~ Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)-N-hydroxy-4-methylpentanamide	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8LO:(2R)-2-[(2,6-diethylphenyl)carbamoylamino]-4-methyl-N-oxidanyl-pentanamide'>8LO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1v OCA], [http://pdbe.org/5y1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y1v RCSB], [http://www.ebi.ac.uk/pdbsum/5y1v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1v ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Addlagatta, A]]
		+	[[Category: Marapaka, A K]]
	[[Category: Zhang, Y]]		[[Category: Zhang, Y]]
-	[[Category: ~~Addlagatta, A~~]]	+	[[Category: Hydrolase-hydrolase inhibitor complex]]
-	[[Category: ~~Marapaka, A.K~~]]	+	[[Category: M1-class aminopeptidase]]

OCA at 04:00, 18 April 2018

OCA — Wed, 18 Apr 2018 04:00:40 GMT

←Older revision		Revision as of 04:00, 18 April 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5y1v is ON HOLD	+	The entry 5y1v is ON HOLD until Paper Publication

	Authors: Marapaka, A.K., Zhang, Y., Addlagatta, A.		Authors: Marapaka, A.K., Zhang, Y., Addlagatta, A.

OCA at 05:55, 21 March 2018

OCA — Wed, 21 Mar 2018 05:55:15 GMT

←Older revision		Revision as of 05:55, 21 March 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5y1v is ON HOLD ~~until Paper Publication~~	+	The entry 5y1v is ON HOLD

	Authors: Marapaka, A.K., Zhang, Y., Addlagatta, A.		Authors: Marapaka, A.K., Zhang, Y., Addlagatta, A.

OCA at 04:49, 3 January 2018

OCA — Wed, 03 Jan 2018 04:49:16 GMT

←Older revision		Revision as of 04:49, 3 January 2018
Line 3:		Line 3:
	The entry 5y1v is ON HOLD until Paper Publication		The entry 5y1v is ON HOLD until Paper Publication

-	Authors: Marapaka, A.K., Addlagatta, A.	+	Authors: Marapaka, A.K., Zhang, Y., Addlagatta, A.

	Description: Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)-N-hydroxy-4-methylpentanamide		Description: Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)-N-hydroxy-4-methylpentanamide
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Marapaka~~, ~~A.K~~]]	+	[[Category: Zhang, Y]]
	[[Category: Addlagatta, A]]		[[Category: Addlagatta, A]]
		+	[[Category: Marapaka, A.K]]

OCA: Protected "5y1v" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 16:02:29 GMT

Protected "5y1v" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:02, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5y1v is ON HOLD until Paper Publication Authors: Marapaka, A.K., Addlagatta, A. Description: Crystal structure of Plasmodium falciparum aminopeptid...

OCA — Wed, 27 Sep 2017 16:02:28 GMT

New page: '''Unreleased structure''' The entry 5y1v is ON HOLD until Paper Publication Authors: Marapaka, A.K., Addlagatta, A. Description: Crystal structure of Plasmodium falciparum aminopeptid...

New page

'''Unreleased structure'''

The entry 5y1v is ON HOLD until Paper Publication

Authors: Marapaka, A.K., Addlagatta, A.

Description: Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)-N-hydroxy-4-methylpentanamide
[[Category: Unreleased Structures]]
[[Category: Marapaka, A.K]]
[[Category: Addlagatta, A]]