5y6n - Revision history

OCA at 08:23, 22 November 2023

OCA — Wed, 22 Nov 2023 08:23:30 GMT

←Older revision		Revision as of 08:23, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='5y6n' size='340' side='right'caption='[[5y6n]], [[Resolution\|resolution]] 1.57Å' scene=''>		<StructureSection load='5y6n' size='340' side='right'caption='[[5y6n]], [[Resolution\|resolution]] 1.57Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5y6n]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Zikv Zikv~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6N OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5Y6N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5y6n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y6N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.571Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5y6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6n OCA], [~~http~~://pdbe.org/5y6n PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5y6n RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5y6n PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6n ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6n OCA], [https://pdbe.org/5y6n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y6n RCSB], [https://www.ebi.ac.uk/pdbsum/5y6n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~A0A140GMI3_ZIKV A0A140GMI3_ZIKV~~]] Peptide 2k: Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[~~SAAS~~:~~SAAS00892720~~]	+	[https://www.uniprot.org/uniprot/POLG_ZIKVF POLG_ZIKVF] Capsid protein C: Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.[UniProtKB:P17763] Capsid protein C: Inhibits RNA silencing by interfering with host Dicer.[UniProtKB:P03314] Peptide pr: Prevents premature fusion activity of envelope proteins in trans-Golgi by binding to envelope protein E at pH6.0. After virion release in extracellular space, gets dissociated from E dimers.[UniProtKB:P17763] Protein prM: Plays a role in host immune defense modulation and protection of envelope protein E during virion synthesis. PrM-E cleavage is ineficient, and immature prM-E proteins could have an activity against host immune response. The sequence of PrM contributes to fetal microcephaly in Humans. Acts as a chaperone for envelope protein E during intracellular virion assembly by masking and inactivating envelope protein E fusion peptide. prM is the only viral peptide matured by host furin in the trans-Golgi network probably to avoid catastrophic activation of the viral fusion activity in acidic Golgi compartment prior to virion release. prM-E cleavage is inefficient, and many virions are only partially matured. These uncleaved prM could play a role in immune evasion.[UniProtKB:P17763]<ref>PMID:28971967</ref> Small envelope protein M: May play a role in virus budding. Exerts cytotoxic effects by activating a mitochondrial apoptotic pathway through M ectodomain. May display a viroporin activity.[UniProtKB:P17763] Envelope protein E: Binds to host cell surface receptor and mediates fusion between viral and cellular membranes. Envelope protein is synthesized in the endoplasmic reticulum in the form of heterodimer with protein prM. They play a role in virion budding in the ER, and the newly formed immature particule is covered with 60 spikes composed of heterodimer between precursor prM and envelope protein E. The virion is transported to the Golgi apparatus where the low pH causes dissociation of PrM-E heterodimers and formation of E homodimers. prM-E cleavage is inefficient, and many virions are only partially matured. These uncleaved prM could play a role in immune evasion.[UniProtKB:P17763] Non-structural protein 1: Involved in immune evasion, pathogenesis and viral replication. Once cleaved off the polyprotein, is targeted to three destinations: the viral replication cycle, the plasma membrane and the extracellular compartment. Essential for viral replication. Required for formation of the replication complex and recruitment of other non-structural proteins to the ER-derived membrane structures. Excreted as a hexameric lipoparticle that plays a role against host immune response. Antagonizing the complement function. Binds to the host macrophages and dendritic cells. Inhibits signal transduction originating from Toll-like receptor 3 (TLR3).[UniProtKB:Q9Q6P4] Non-structural protein 2A: Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host alpha/beta interferon antiviral response (By similarity). Disrupts adherens junction formation and thereby impairs proliferation of radial cells in both embryonic mouse cortex and human forebrain organoids (PubMed:28826723).[UniProtKB:P14335]<ref>PMID:28826723</ref> Non-structural protein 2B: Required cofactor for the serine protease function of NS3.[UniProtKB:Q32ZE1] Serine protease NS3: Displays three enzymatic activities: serine protease, NTPase and RNA helicase. NS3 serine protease, in association with NS2B, performs its autocleavage and cleaves the polyprotein at dibasic sites in the cytoplasm: C-prM, NS2A-NS2B, NS2B-NS3, NS3-NS4A, NS4A-2K and NS4B-NS5. NS3 RNA helicase binds RNA and unwinds dsRNA in the 3' to 5' direction (By similarity). Leads to translation arrest when expressed ex vivo (PubMed:28592527).[UniProtKB:Q32ZE1]<ref>PMID:28592527</ref> Non-structural protein 4A: Regulates the ATPase activity of the NS3 helicase activity. NS4A allows NS3 helicase to conserve energy during unwinding (By similarity). Cooperatively with NS4B suppress the Akt-mTOR pathway and lead to cellular dysregulation (PubMed:27524440). Leads to translation arrest when expressed ex vivo (PubMed:28592527).[UniProtKB:Q9Q6P4]<ref>PMID:27524440</ref> <ref>PMID:28592527</ref> Peptide 2k: Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter. Non-structural protein 4B: Induces the formation of ER-derived membrane vesicles where the viral replication takes place. Inhibits interferon (IFN)-induced host STAT1 phosphorylation and nuclear translocation, thereby preventing the establishment of cellular antiviral state by blocking the IFN-alpha/beta pathway. Inhibits STAT2 translocation in the nucleus after IFN-alpha treatment (By similarity). Cooperatively with NS4A suppress the Akt-mTOR pathway and lead to cellular dysregulation (PubMed:27524440).[UniProtKB:Q9Q6P4]<ref>PMID:27524440</ref> RNA-directed RNA polymerase NS5: Replicates the viral (+) and (-) RNA genome, and performs the capping of genomes in the cytoplasm. NS5 methylates viral RNA cap at guanine N-7 and ribose 2'-O positions. Besides its role in RNA genome replication, also prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) signaling pathway. Inhibits host TYK2 and STAT2 phosphorylation, thereby preventing activation of JAK-STAT signaling pathway.[UniProtKB:Q9Q6P4]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5y6n" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5y6n" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Helicase 3D structures\|Helicase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Zikv~~]]	+	[[Category: Zika virus]]
-	[[Category: Chen, C]]	+	[[Category: Chen C]]
-	[[Category: Chi, H]]	+	[[Category: Chi H]]
-	[[Category: Ji~~, X Y~~]]	+	[[Category: Ji XY]]
-	[[Category: Liu~~, X H~~]]	+	[[Category: Liu XH]]
-	[[Category: Mu~~, Z Y~~]]	+	[[Category: Mu ZY]]
-	[[Category: Tian~~, H L~~]]	+	[[Category: Tian HL]]
-	[[Category: Wang~~, Z F~~]]	+	[[Category: Wang ZF]]
-	[[Category: Yang~~, H T~~]]	+	[[Category: Yang HT]]
-	[[Category: Yang~~, K L~~]]	+	[[Category: Yang KL]]
-	[[Category: Yang~~, X Y~~]]	+	[[Category: Yang XY]]
-	[[Category: Zhang~~, T Q~~]]	+	[[Category: Zhang TQ]]
-	[[Category: Zhao, Q]]	+	[[Category: Zhao Q]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolysis]]~~	+
-	~~[[Category: Zika virus helicase~~]]	+

OCA at 09:12, 21 October 2020

OCA — Wed, 21 Oct 2020 09:12:20 GMT

←Older revision		Revision as of 09:12, 21 October 2020
Line 1:		Line 1:

	==Zika virus helicase in complex with ADP==		==Zika virus helicase in complex with ADP==
-	<StructureSection load='5y6n' size='340' side='right' caption='[[5y6n]], [[Resolution\|resolution]] 1.57Å' scene=''>	+	<StructureSection load='5y6n' size='340' side='right'caption='[[5y6n]], [[Resolution\|resolution]] 1.57Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5y6n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zikv Zikv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6N OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5Y6N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5y6n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zikv Zikv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5Y6N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5y6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6n OCA], [http://pdbe.org/5y6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y6n RCSB], [http://www.ebi.ac.uk/pdbsum/5y6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6n ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5y6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6n OCA], [http://pdbe.org/5y6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y6n RCSB], [http://www.ebi.ac.uk/pdbsum/5y6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Zikv]]		[[Category: Zikv]]
	[[Category: Chen, C]]		[[Category: Chen, C]]

OCA at 08:29, 17 October 2018

OCA — Wed, 17 Oct 2018 08:29:49 GMT

←Older revision		Revision as of 08:29, 17 October 2018
Line 3:		Line 3:
	<StructureSection load='5y6n' size='340' side='right' caption='[[5y6n]], [[Resolution\|resolution]] 1.57Å' scene=''>		<StructureSection load='5y6n' size='340' side='right' caption='[[5y6n]], [[Resolution\|resolution]] 1.57Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5y6n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y6N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5y6n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zikv Zikv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y6N FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6n OCA], [http://pdbe.org/5y6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y6n RCSB], [http://www.ebi.ac.uk/pdbsum/5y6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6n ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6n OCA], [http://pdbe.org/5y6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y6n RCSB], [http://www.ebi.ac.uk/pdbsum/5y6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6n ProSAT]</span></td></tr>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Zikv]]
	[[Category: Chen, C]]		[[Category: Chen, C]]
	[[Category: Chi, H]]		[[Category: Chi, H]]

OCA at 07:08, 4 July 2018

OCA — Wed, 04 Jul 2018 07:08:52 GMT

←Older revision		Revision as of 07:08, 4 July 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5y6n is ~~ON HOLD until Paper~~ Publication	+	==Zika virus helicase in complex with ADP==
		+	<StructureSection load='5y6n' size='340' side='right' caption='[[5y6n]], [[Resolution\|resolution]] 1.57Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5y6n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y6N FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6n OCA], [http://pdbe.org/5y6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y6n RCSB], [http://www.ebi.ac.uk/pdbsum/5y6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6n ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/A0A140GMI3_ZIKV A0A140GMI3_ZIKV]] Peptide 2k: Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[SAAS:SAAS00892720]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	During its life cycle, Zika virus (ZIKV), an arthropod-borne flavivirus that is associated with Guillain-Barre syndrome and causes microencephaly in fetuses and newborn children, encodes a critical and indispensable helicase domain that has 5'-triphosphatase activity and performs ATP hydrolysis to generate energy and thus, sustains unwinding of double-stranded RNA during ZIKV genome replication. Of these processes, ATP hydrolysis represents the most basic event; however, its dynamic mechanisms remain largely unknown, impeding the further understanding of the function of ZIKV helicase and the ongoing anti-ZIKV drug design. In this work, we determined the crystal structure of ZIKV helicase in complex with ADP-AlF3-Mn(2+) and ADP-Mn(2+) separately. The structural analysis indicates that these structures represent the intermediate state and posthydrolysis state, respectively, of the ATP hydrolysis process of ZIKV helicase. These findings, together with our earlier work, which identified the prehydrolysis state of ZIKV helicase, lead to a proposal of the ATP hydrolysis cycle for ZIKV helicase. On this basis, we used site-directed mutagenesis combined with an enzymatic study to identify successfully residues that are critical for the ATPase activity of ZIKV helicase; this will provide new ideas to understand the function for the key enzyme of ZIKV.-Yang, X., Chen, C., Tian, H., Chi, H., Mu, Z., Zhang, T., Yang, K., Zhao, Q., Liu, X., Wang, Z., Ji, X., Yang, H. Mechanism of ATP hydrolysis by the Zika virus helicase.

-	~~Authors:~~ Yang, X~~.Y.~~, Chen, C., Tian, H~~.L.~~, Chi, H., Mu, Z~~.Y.~~, Zhang, T~~.Q.~~, Yang, K~~.L.~~, Zhao, Q., Liu, X~~.H.~~, Wang, Z~~.F.~~, Ji, X~~.Y.~~, Yang, H.T.	+	Mechanism of ATP hydrolysis by the Zika virus helicase.,Yang X, Chen C, Tian H, Chi H, Mu Z, Zhang T, Yang K, Zhao Q, Liu X, Wang Z, Ji X, Yang H FASEB J. 2018 Apr 17:fj201701140R. doi: 10.1096/fj.201701140R. PMID:29913559<ref>PMID:29913559</ref>

-	~~Description: Zika virus helicase in complex with ADP~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category: Zhang~~, T.~~Q]]~~	+	<div class="pdbe-citations 5y6n" style="background-color:#fffaf0;"></div>
-	~~[[Category: Yang, H~~.~~T]]~~	+	== References ==
-	~~[[Category: Yang, X~~.~~Y]]~~	+	<references/>
-	~~[[Category: Chi, H]]~~	+	__TOC__
-	~~[[Category~~: ~~Wang, Z.F]]~~	+	</StructureSection>
-	~~[[Category: Ji, X.Y]]~~	+
-	~~[[Category: Yang, K.L]]~~	+
-	~~[[Category: Liu, X.H]]~~	+
-	~~[[Category: Mu, Z.Y]]~~	+
	[[Category: Chen, C]]		[[Category: Chen, C]]
-	[[Category: Tian, H.L]]	+	[[Category: Chi, H]]
		+	[[Category: Ji, X Y]]
		+	[[Category: Liu, X H]]
		+	[[Category: Mu, Z Y]]
		+	[[Category: Tian, H L]]
		+	[[Category: Wang, Z F]]
		+	[[Category: Yang, H T]]
		+	[[Category: Yang, K L]]
		+	[[Category: Yang, X Y]]
		+	[[Category: Zhang, T Q]]
	[[Category: Zhao, Q]]		[[Category: Zhao, Q]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolysis]]
		+	[[Category: Zika virus helicase]]

OCA at 04:02, 6 June 2018

OCA — Wed, 06 Jun 2018 04:02:46 GMT

←Older revision		Revision as of 04:02, 6 June 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5y6n is ON HOLD	+	The entry 5y6n is ON HOLD until Paper Publication

	Authors: Yang, X.Y., Chen, C., Tian, H.L., Chi, H., Mu, Z.Y., Zhang, T.Q., Yang, K.L., Zhao, Q., Liu, X.H., Wang, Z.F., Ji, X.Y., Yang, H.T.		Authors: Yang, X.Y., Chen, C., Tian, H.L., Chi, H., Mu, Z.Y., Zhang, T.Q., Yang, K.L., Zhao, Q., Liu, X.H., Wang, Z.F., Ji, X.Y., Yang, H.T.

OCA at 04:01, 18 April 2018

OCA — Wed, 18 Apr 2018 04:01:02 GMT

←Older revision		Revision as of 04:01, 18 April 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5y6n is ON HOLD ~~until Paper Publication~~	+	The entry 5y6n is ON HOLD

	Authors: Yang, X.Y., Chen, C., Tian, H.L., Chi, H., Mu, Z.Y., Zhang, T.Q., Yang, K.L., Zhao, Q., Liu, X.H., Wang, Z.F., Ji, X.Y., Yang, H.T.		Authors: Yang, X.Y., Chen, C., Tian, H.L., Chi, H., Mu, Z.Y., Zhang, T.Q., Yang, K.L., Zhao, Q., Liu, X.H., Wang, Z.F., Ji, X.Y., Yang, H.T.

-	Description: ~~Structure of viral~~ helicase	+	Description: Zika virus helicase in complex with ADP
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Zhang, T.Q]]		[[Category: Zhang, T.Q]]
-	[[Category: Ji, X.~~Y]]~~	+	[[Category: Yang, H.T]]
-	~~[[Category: Liu, X.H~~]]	+
	[[Category: Yang, X.Y]]		[[Category: Yang, X.Y]]
		+	[[Category: Chi, H]]
		+	[[Category: Wang, Z.F]]
		+	[[Category: Ji, X.Y]]
	[[Category: Yang, K.L]]		[[Category: Yang, K.L]]
		+	[[Category: Liu, X.H]]
	[[Category: Mu, Z.Y]]		[[Category: Mu, Z.Y]]
-	[[Category: Tian, H.L]]
-	[[Category: Wang, Z.F]]
-	[[Category: Yang, H.T]]
-	[[Category: Chi, H]]
	[[Category: Chen, C]]		[[Category: Chen, C]]
		+	[[Category: Tian, H.L]]
	[[Category: Zhao, Q]]		[[Category: Zhao, Q]]

OCA: Protected "5y6n" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 16:12:30 GMT

Protected "5y6n" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:12, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 5y6n is ON HOLD until Paper Publication Authors: Yang, X.Y., Chen, C., Tian, H.L., Chi, H., Mu, Z.Y., Zhang, T.Q., Yang, K.L., Zhao, Q., Liu, X.H., ...

OCA — Wed, 27 Sep 2017 16:12:29 GMT

New page: '''Unreleased structure''' The entry 5y6n is ON HOLD until Paper Publication Authors: Yang, X.Y., Chen, C., Tian, H.L., Chi, H., Mu, Z.Y., Zhang, T.Q., Yang, K.L., Zhao, Q., Liu, X.H., ...

New page

'''Unreleased structure'''

The entry 5y6n is ON HOLD until Paper Publication

Authors: Yang, X.Y., Chen, C., Tian, H.L., Chi, H., Mu, Z.Y., Zhang, T.Q., Yang, K.L., Zhao, Q., Liu, X.H., Wang, Z.F., Ji, X.Y., Yang, H.T.

Description: Structure of viral helicase
[[Category: Unreleased Structures]]
[[Category: Zhang, T.Q]]
[[Category: Ji, X.Y]]
[[Category: Liu, X.H]]
[[Category: Yang, X.Y]]
[[Category: Yang, K.L]]
[[Category: Mu, Z.Y]]
[[Category: Tian, H.L]]
[[Category: Wang, Z.F]]
[[Category: Yang, H.T]]
[[Category: Chi, H]]
[[Category: Chen, C]]
[[Category: Zhao, Q]]