5z0v - Revision history

OCA at 08:43, 22 November 2023

OCA — Wed, 22 Nov 2023 08:43:38 GMT

←Older revision		Revision as of 08:43, 22 November 2023
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	==Structural insight into the Zika virus capsid encapsulating the viral genome==		==Structural insight into the Zika virus capsid encapsulating the viral genome==
-	<StructureSection load='5z0v' size='340' side='right' caption='[[5z0v]], [[Resolution\|resolution]] 2.91Å' scene=''>	+	<StructureSection load='5z0v' size='340' side='right'caption='[[5z0v]], [[Resolution\|resolution]] 2.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5z0v]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Zikv Zikv~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z0V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5Z0V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5z0v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)] and [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z0V FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=MAL:MALTOSE'>MAL</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.913Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~ECBD_4002 ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=64320 ZIKV])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5z0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z0v OCA], [~~http~~://pdbe.org/5z0v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5z0v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5z0v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5z0v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z0v OCA], [https://pdbe.org/5z0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z0v RCSB], [https://www.ebi.ac.uk/pdbsum/5z0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z0v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~A0A140NCD0_ECOBD A0A140NCD0_ECOBD]~~] Involved in the high-affinity maltose membrane transport system. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[~~RuleBase~~:~~RU365005~~]	+	[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/POLG_ZIKV POLG_ZIKV] Protein C: Encapsulates the genomic RNA.[UniProtKB:P17763] prM: Acts as a chaperone for envelope protein E during intracellular virion assembly by masking and inactivating envelope protein E fusion peptide. prM is matured in the last step of virion assembly, presumably to avoid catastrophic activation of the viral fusion peptide induced by the acidic pH of the trans-Golgi network. After cleavage by host furin, the pr peptide is released in the extracellular medium and small envelope protein M and envelope protein E homodimers are dissociated.[UniProtKB:P17763] Envelope protein E: Binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes.[UniProtKB:P17763] Non-structural protein 1: Involved in virus replication and regulation of the innate immune response.[UniProtKB:P17763] Non-structural protein 2A: May be involved viral RNA replication and capsid assembly.[UniProtKB:P09732] Non-structural protein 4A: Induces host endoplasmic reticulum membrane rearrangements leading to the formation of virus-induced membranous vesicles hosting the dsRNA and polymerase, functioning as a replication complex. NS4A might also regulate the ATPase activity of the helicase region of Serine protease NS3 chain.[UniProtKB:P17763] Peptide 2k: Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[UniProtKB:P17763] Non-structural protein 4B: Inhibits interferon (IFN)-induced host STAT1 phosphorylation and nuclear translocation, thereby preventing the establishment of cellular antiviral state by blocking the IFN-alpha/beta pathway.[UniProtKB:P17763]
		+
		+	==See Also==
		+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Zikv]]~~	+	[[Category: Large Structures]]
-	~~[[Category: Chen, C]]~~	+
-	~~[[Category: Duan, Y]]~~	+
-	~~[[Category: Ji, X]]~~	+
-	~~[[Category: Li, T]]~~	+
-	~~[[Category: Mi, K]]~~	+
-	~~[[Category: Wang, Z]]~~	+
-	~~[[Category: Wu, C]]~~	+
-	~~[[Category: Xue, X]]~~	+
-	~~[[Category: Yang, H]]~~	+
-	~~[[Category: Yang, K]]~~	+
-	~~[[Category: Yang, X]]~~	+
-	~~[[Category: Zhang, T]]~~	+
-	~~[[Category: Zhao, Q]]~~	+
-	~~[[Category: Capsid]]~~	+
-	~~[[Category: Viral protein~~]]	+
	[[Category: Zika virus]]		[[Category: Zika virus]]
		+	[[Category: Chen C]]
		+	[[Category: Duan Y]]
		+	[[Category: Ji X]]
		+	[[Category: Li T]]
		+	[[Category: Mi K]]
		+	[[Category: Wang Z]]
		+	[[Category: Wu C]]
		+	[[Category: Xue X]]
		+	[[Category: Yang H]]
		+	[[Category: Yang K]]
		+	[[Category: Yang X]]
		+	[[Category: Zhang T]]
		+	[[Category: Zhao Q]]

OCA at 08:28, 2 May 2018

OCA — Wed, 02 May 2018 08:28:08 GMT

←Older revision		Revision as of 08:28, 2 May 2018
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	<StructureSection load='5z0v' size='340' side='right' caption='[[5z0v]], [[Resolution\|resolution]] 2.91Å' scene=''>		<StructureSection load='5z0v' size='340' side='right' caption='[[5z0v]], [[Resolution\|resolution]] 2.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5z0v]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z0V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5z0v]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Zikv Zikv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z0V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ECBD_4002 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=64320 ZIKV])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z0v OCA], [http://pdbe.org/5z0v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z0v RCSB], [http://www.ebi.ac.uk/pdbsum/5z0v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z0v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z0v OCA], [http://pdbe.org/5z0v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z0v RCSB], [http://www.ebi.ac.uk/pdbsum/5z0v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z0v ProSAT]</span></td></tr>
	</table>		</table>
Line 11:		Line 12:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Zikv]]
	[[Category: Chen, C]]		[[Category: Chen, C]]
	[[Category: Duan, Y]]		[[Category: Duan, Y]]

OCA at 13:49, 11 April 2018

OCA — Wed, 11 Apr 2018 13:49:11 GMT

←Older revision		Revision as of 13:49, 11 April 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5z0v is ~~ON HOLD until Paper Publication~~	+	==Structural insight into the Zika virus capsid encapsulating the viral genome==
-		+	<StructureSection load='5z0v' size='340' side='right' caption='[[5z0v]], [[Resolution\|resolution]] 2.91Å' scene=''>
-	~~Authors~~: ~~Li, T~~.~~, Zhao, Q~~.~~, Yang, X~~.~~, Chen, C~~., ~~Yang, K~~.~~, Wu, C~~.~~, Zhang, T~~., ~~Duan, Y~~., ~~Xue, X~~.~~, Mi, K~~.~~, Ji, X~~., ~~Wang, Z~~., ~~Yang, H~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5z0v]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z0V FirstGlance]. <br>
-	~~Description~~: ~~Structural insight into~~ the ~~Zika virus capsid encapsulating~~ the ~~viral genome~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z0v OCA], [http://pdbe.org/5z0v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z0v RCSB], [http://www.ebi.ac.uk/pdbsum/5z0v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z0v ProSAT]</span></td></tr>
-	[[Category: ~~Yang~~, X]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/A0A140NCD0_ECOBD A0A140NCD0_ECOBD]] Involved in the high-affinity maltose membrane transport system. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[RuleBase:RU365005]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chen, C]]
		+	[[Category: Duan, Y]]
		+	[[Category: Ji, X]]
		+	[[Category: Li, T]]
	[[Category: Mi, K]]		[[Category: Mi, K]]
-	[[Category: ~~Zhang~~, T]]	+	[[Category: Wang, Z]]
	[[Category: Wu, C]]		[[Category: Wu, C]]
-	[[Category: Li, T]]
-	[[Category: Duan, Y]]
-	[[Category: Yang, K]]
	[[Category: Xue, X]]		[[Category: Xue, X]]
	[[Category: Yang, H]]		[[Category: Yang, H]]
-	[[Category: Ji, X]]	+	[[Category: Yang, K]]
-	[[Category: ~~Wang~~, Z]]	+	[[Category: Yang, X]]
-	[[Category: ~~Chen~~, C]]	+	[[Category: Zhang, T]]
	[[Category: Zhao, Q]]		[[Category: Zhao, Q]]
		+	[[Category: Capsid]]
		+	[[Category: Viral protein]]
		+	[[Category: Zika virus]]

OCA at 05:30, 17 January 2018

OCA — Wed, 17 Jan 2018 05:30:57 GMT

←Older revision		Revision as of 05:30, 17 January 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5z0v is ON HOLD	+	The entry 5z0v is ON HOLD until Paper Publication

	Authors: Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.		Authors: Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.
Line 9:		Line 9:
	[[Category: Yang, X]]		[[Category: Yang, X]]
	[[Category: Mi, K]]		[[Category: Mi, K]]
-	[[Category: Xue, X]]
-	[[Category: Yang, H]]
	[[Category: Zhang, T]]		[[Category: Zhang, T]]
	[[Category: Wu, C]]		[[Category: Wu, C]]
-	[[Category: Ji, X]]
	[[Category: Li, T]]		[[Category: Li, T]]
-	[[Category: Wang, Z]]
	[[Category: Duan, Y]]		[[Category: Duan, Y]]
	[[Category: Yang, K]]		[[Category: Yang, K]]
		+	[[Category: Xue, X]]
		+	[[Category: Yang, H]]
		+	[[Category: Ji, X]]
		+	[[Category: Wang, Z]]
	[[Category: Chen, C]]		[[Category: Chen, C]]
	[[Category: Zhao, Q]]		[[Category: Zhao, Q]]

OCA: Protected "5z0v" [edit=sysop:move=sysop]

OCA — Wed, 27 Dec 2017 07:14:47 GMT

Protected "5z0v" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:14, 27 December 2017

OCA: New page: '''Unreleased structure''' The entry 5z0v is ON HOLD Authors: Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H. D...

OCA — Wed, 27 Dec 2017 07:14:46 GMT

New page: '''Unreleased structure''' The entry 5z0v is ON HOLD Authors: Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H. D...

New page

'''Unreleased structure'''

The entry 5z0v is ON HOLD

Authors: Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.

Description: Structural insight into the Zika virus capsid encapsulating the viral genome
[[Category: Unreleased Structures]]
[[Category: Yang, X]]
[[Category: Mi, K]]
[[Category: Xue, X]]
[[Category: Yang, H]]
[[Category: Zhang, T]]
[[Category: Wu, C]]
[[Category: Ji, X]]
[[Category: Li, T]]
[[Category: Wang, Z]]
[[Category: Duan, Y]]
[[Category: Yang, K]]
[[Category: Chen, C]]
[[Category: Zhao, Q]]