5zgm - Revision history

OCA at 08:54, 22 November 2023

OCA — Wed, 22 Nov 2023 08:54:05 GMT

←Older revision		Revision as of 08:54, 22 November 2023
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	<StructureSection load='5zgm' size='340' side='right'caption='[[5zgm]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='5zgm' size='340' side='right'caption='[[5zgm]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zgm]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Mustelus_griseus Mustelus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZGM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5ZGM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zgm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mustelus_griseus Mustelus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZGM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.399Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5zgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zgm OCA], [~~http~~://pdbe.org/5zgm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5zgm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5zgm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5zgm ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zgm OCA], [https://pdbe.org/5zgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zgm RCSB], [https://www.ebi.ac.uk/pdbsum/5zgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zgm ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PRVA_TRISE PRVA_TRISE] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Mustelus griseus]]		[[Category: Mustelus griseus]]
-	[[Category: Cao~~, M J~~]]	+	[[Category: Cao MJ]]
-	[[Category: Chen~~, Y L~~]]	+	[[Category: Chen YL]]
-	[[Category: Jin~~, T C~~]]	+	[[Category: Jin TC]]
-	[[Category: Yang~~, R Q]]~~	+	[[Category: Yang RQ]]
-	~~[[Category: Allergen]]~~	+
-	~~[[Category: Food allergen]]~~	+
-	~~[[Category: Parvalbumin~~]]	+

OCA at 21:19, 28 October 2020

OCA — Wed, 28 Oct 2020 21:19:28 GMT

←Older revision		Revision as of 21:19, 28 October 2020
Line 1:		Line 1:

	==Crystal Structure of Parvalbumin SPVI, the Major Allergens in Mustelus griseus==		==Crystal Structure of Parvalbumin SPVI, the Major Allergens in Mustelus griseus==
-	<StructureSection load='5zgm' size='340' side='right' caption='[[5zgm]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='5zgm' size='340' side='right'caption='[[5zgm]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zgm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mustelus_griseus Mustelus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZGM OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ZGM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zgm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mustelus_griseus Mustelus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZGM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ZGM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5zgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zgm OCA], [http://pdbe.org/5zgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zgm RCSB], [http://www.ebi.ac.uk/pdbsum/5zgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zgm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5zgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zgm OCA], [http://pdbe.org/5zgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zgm RCSB], [http://www.ebi.ac.uk/pdbsum/5zgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zgm ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 5zgm" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5zgm" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Parvalbumin\|Parvalbumin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mustelus griseus]]		[[Category: Mustelus griseus]]
	[[Category: Cao, M J]]		[[Category: Cao, M J]]

OCA at 22:05, 9 August 2018

OCA — Thu, 09 Aug 2018 22:05:12 GMT

←Older revision		Revision as of 22:05, 9 August 2018
Line 3:		Line 3:
	<StructureSection load='5zgm' size='340' side='right' caption='[[5zgm]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='5zgm' size='340' side='right' caption='[[5zgm]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zgm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Triakis_semifasciata Triakis semifasciata~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZGM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZGM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zgm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mustelus_griseus Mustelus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZGM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZGM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zgm OCA], [http://pdbe.org/5zgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zgm RCSB], [http://www.ebi.ac.uk/pdbsum/5zgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zgm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zgm OCA], [http://pdbe.org/5zgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zgm RCSB], [http://www.ebi.ac.uk/pdbsum/5zgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zgm ProSAT]</span></td></tr>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Triakis semifasciata~~]]	+	[[Category: Mustelus griseus]]
	[[Category: Cao, M J]]		[[Category: Cao, M J]]
	[[Category: Chen, Y L]]		[[Category: Chen, Y L]]

OCA at 18:40, 1 August 2018

OCA — Wed, 01 Aug 2018 18:40:00 GMT

←Older revision		Revision as of 18:40, 1 August 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5zgm is ~~ON HOLD until Paper~~ Publication	+	==Crystal Structure of Parvalbumin SPVI, the Major Allergens in Mustelus griseus==
		+	<StructureSection load='5zgm' size='340' side='right' caption='[[5zgm]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5zgm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Triakis_semifasciata Triakis semifasciata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZGM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZGM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zgm OCA], [http://pdbe.org/5zgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zgm RCSB], [http://www.ebi.ac.uk/pdbsum/5zgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zgm ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fish play important roles in human nutrition and health, but also trigger allergic reactions in some population. Parvalbumin (PV) represents the major allergen of fish. While IgE cross-reactivity to PV in various bony fish species has been well characterized, little information is available about allergens in cartilaginous fish. In this study, two shark PV isoforms (named as SPV-I and SPV-II) from Mustelus griseus were purified. Their identities were further confirmed by mass spectroscopic analysis. IgE immunoblot analysis showed that sera from fish-allergic patients reacted to both SPV-I and SPV-II, but the majority of sera reacted more intensely to SPV-I than SPV-II. Thermal denaturation monitored by CD spectrum showed that both of the SPV allergens are highly thermostable. SPV-I maintained its IgE-binding capability after heat denaturation, while the IgE-binding capability of SPV-II was reduced. The results of crystal structure showed that SPV-I and SPV-II were similar in their overall tertiary structure, but their amino acid sequences shared lower similarities, indicating that the differences in the IgE-binding capabilities of SPV-I and SPV-II might be due to differential antigen epitopes in these two isoforms.

-	~~Authors: Yang~~, ~~R.Q~~., Chen, ~~Y.L.~~, ~~Jin~~, T~~.C.~~, Cao~~, M.~~J.	+	Purification, Characterization, and Crystal Structure of Parvalbumins, the Major Allergens in Mustelus griseus.,Yang RQ, Chen YL, Chen F, Wang H, Zhang Q, Liu GM, Jin T, Cao MJ J Agric Food Chem. 2018 Jul 17. doi: 10.1021/acs.jafc.8b01889. PMID:29969026<ref>PMID:29969026</ref>

-	~~Description: Crystal Structure of Parvalbumin SPVI~~, the ~~Major Allergens in Mustelus griseus~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: ~~Yang~~, ~~R.Q~~]]	+	<div class="pdbe-citations 5zgm" style="background-color:#fffaf0;"></div>
-	[[Category: Chen, Y.L]]	+	== References ==
-	[[Category: ~~Cao~~, ~~M.J~~]]	+	<references/>
-	[[Category: ~~Jin~~, ~~T.C~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Triakis semifasciata]]
		+	[[Category: Cao, M J]]
		+	[[Category: Chen, Y L]]
		+	[[Category: Jin, T C]]
		+	[[Category: Yang, R Q]]
		+	[[Category: Allergen]]
		+	[[Category: Food allergen]]
		+	[[Category: Parvalbumin]]

OCA at 05:08, 28 March 2018

OCA — Wed, 28 Mar 2018 05:08:23 GMT

←Older revision		Revision as of 05:08, 28 March 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zgm is ON HOLD	+	The entry 5zgm is ON HOLD until Paper Publication

	Authors: Yang, R.Q., Chen, Y.L., Jin, T.C., Cao, M.J.		Authors: Yang, R.Q., Chen, Y.L., Jin, T.C., Cao, M.J.

OCA: Protected "5zgm" [edit=sysop:move=sysop]

OCA — Wed, 14 Mar 2018 05:03:09 GMT

Protected "5zgm" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:03, 14 March 2018

OCA: New page: '''Unreleased structure''' The entry 5zgm is ON HOLD Authors: Yang, R.Q., Chen, Y.L., Jin, T.C., Cao, M.J. Description: Crystal Structure of Parvalbumin SPVI, the Major Allergens in Mu...

OCA — Wed, 14 Mar 2018 05:03:08 GMT

New page: '''Unreleased structure''' The entry 5zgm is ON HOLD Authors: Yang, R.Q., Chen, Y.L., Jin, T.C., Cao, M.J. Description: Crystal Structure of Parvalbumin SPVI, the Major Allergens in Mu...

New page

'''Unreleased structure'''

The entry 5zgm is ON HOLD

Authors: Yang, R.Q., Chen, Y.L., Jin, T.C., Cao, M.J.

Description: Crystal Structure of Parvalbumin SPVI, the Major Allergens in Mustelus griseus
[[Category: Unreleased Structures]]
[[Category: Yang, R.Q]]
[[Category: Chen, Y.L]]
[[Category: Cao, M.J]]
[[Category: Jin, T.C]]