5zui - Revision history

OCA at 09:07, 22 November 2023

OCA — Wed, 22 Nov 2023 09:07:38 GMT

←Older revision		Revision as of 09:07, 22 November 2023
Line 3:		Line 3:
	<StructureSection load='5zui' size='340' side='right'caption='[[5zui]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='5zui' size='340' side='right'caption='[[5zui]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zui]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Cbs_144.50 Cbs 144.50~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZUI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zui]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZUI FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ADP:ADENOSINE~~-~~5-DIPHOSPHATE'>ADP</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.701Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~CTHT_0022720 ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=209285 CBS 144.50])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zui OCA], [https://pdbe.org/5zui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zui RCSB], [https://www.ebi.ac.uk/pdbsum/5zui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zui ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zui OCA], [https://pdbe.org/5zui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zui RCSB], [https://www.ebi.ac.uk/pdbsum/5zui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zui ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G0S4G4_CHATD G0S4G4_CHATD]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cbs 144 50~~]]	+	[[Category: Chaetomium thermophilum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hanazono, Y]]	+	[[Category: Hanazono Y]]
-	[[Category: Inoue, Y]]	+	[[Category: Inoue Y]]
-	[[Category: Miki, K]]	+	[[Category: Miki K]]
-	[[Category: Noguchi, K]]	+	[[Category: Noguchi K]]
-	[[Category: Shinohara, K]]	+	[[Category: Shinohara K]]
-	[[Category: Takeda, K]]	+	[[Category: Takeda K]]
-	[[Category: Yohda, M]]	+	[[Category: Yohda M]]
-	~~[[Category: Atpase]]~~	+
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: Helical filament]]~~	+
-	~~[[Category: Protein disaggregase]]~~	+
-	~~[[Category: Two-ring aaa protein~~]]	+

OCA at 05:24, 28 April 2021

OCA — Wed, 28 Apr 2021 05:24:41 GMT

←Older revision		Revision as of 05:24, 28 April 2021
Line 3:		Line 3:
	<StructureSection load='5zui' size='340' side='right'caption='[[5zui]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='5zui' size='340' side='right'caption='[[5zui]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zui]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cbs_144.50 Cbs 144.50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZUI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ZUI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zui]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cbs_144.50 Cbs 144.50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZUI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0022720 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=209285 CBS 144.50])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0022720 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=209285 CBS 144.50])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5zui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zui OCA], [~~http~~://pdbe.org/5zui PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5zui RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5zui PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5zui ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zui OCA], [https://pdbe.org/5zui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zui RCSB], [https://www.ebi.ac.uk/pdbsum/5zui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zui ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Hsp104 and its bacterial homolog ClpB form hexameric ring structures and mediate protein disaggregation. The disaggregated polypeptide is thought to thread through the central channel of the ring. However, the dynamic behavior of Hsp104 during disaggregation remains unclear. Here, we reported the stochastic conformational dynamics and a split conformation of Hsp104 disaggregase from Chaetomium thermophilum (CtHsp104) in the presence of ADP by X-ray crystallography, cryo-electron microscopy (EM), and high-speed atomic force microscopy (AFM). ADP-bound CtHsp104 assembles into a 65 left-handed spiral filament in the crystal structure at a resolution of 2.7 A. The unit of the filament is a hexamer of the split spiral structure. In the cryo-EM images, staggered and split hexameric rings were observed. Further, high-speed AFM observations showed that a substrate addition enhanced the conformational change and increased the split structure's frequency. Our data suggest that split conformation is an off-pathway state of CtHsp104 during disaggregation.
		+
		+	Split conformation of Chaetomium thermophilum Hsp104 disaggregase.,Inoue Y, Hanazono Y, Noi K, Kawamoto A, Kimatsuka M, Harada R, Takeda K, Kita R, Iwamasa N, Shibata K, Noguchi K, Shigeta Y, Namba K, Ogura T, Miki K, Shinohara K, Yohda M Structure. 2021 Feb 25. pii: S0969-2126(21)00046-0. doi:, 10.1016/j.str.2021.02.002. PMID:33651974<ref>PMID:33651974</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5zui" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]		*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:01, 16 October 2019

OCA — Wed, 16 Oct 2019 07:01:54 GMT

←Older revision		Revision as of 07:01, 16 October 2019
Line 3:		Line 3:
	<StructureSection load='5zui' size='340' side='right'caption='[[5zui]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='5zui' size='340' side='right'caption='[[5zui]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zui]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZUI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zui]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_144.50 Cbs 144.50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZUI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0022720 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=209285 CBS 144.50])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zui OCA], [http://pdbe.org/5zui PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zui RCSB], [http://www.ebi.ac.uk/pdbsum/5zui PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zui ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zui OCA], [http://pdbe.org/5zui PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zui RCSB], [http://www.ebi.ac.uk/pdbsum/5zui PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zui ProSAT]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Cbs 144 50]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Hanazono, Y]]		[[Category: Hanazono, Y]]

OCA at 05:45, 19 June 2019

OCA — Wed, 19 Jun 2019 05:45:20 GMT

←Older revision		Revision as of 05:45, 19 June 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5zui ~~is ON HOLD until Paper Publication~~	+	==Crystal Structure of HSP104 from Chaetomium thermophilum==
-		+	<StructureSection load='5zui' size='340' side='right'caption='[[5zui]], [[Resolution\|resolution]] 2.70Å' scene=''>
-	~~Authors~~: ~~Hanazono, Y~~., ~~Inoue, Y~~., ~~Noguchi, K~~., ~~Yohda, M~~., ~~Shinohara, K~~., ~~Takeda, K~~., ~~Miki, K~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5zui]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZUI FirstGlance]. <br>
-	~~Description: Crystal Structure of HSP104 from Chaetomium thermophilum~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zui OCA], [http://pdbe.org/5zui PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zui RCSB], [http://www.ebi.ac.uk/pdbsum/5zui PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zui ProSAT]</span></td></tr>
-	[[Category: ~~Takeda~~, K]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Hanazono, Y]]
		+	[[Category: Inoue, Y]]
		+	[[Category: Miki, K]]
	[[Category: Noguchi, K]]		[[Category: Noguchi, K]]
-	[[Category: Inoue, Y]]
-	[[Category: Hanazono, Y]]
	[[Category: Shinohara, K]]		[[Category: Shinohara, K]]
-	[[Category: ~~Miki~~, K]]	+	[[Category: Takeda, K]]
	[[Category: Yohda, M]]		[[Category: Yohda, M]]
		+	[[Category: Atpase]]
		+	[[Category: Chaperone]]
		+	[[Category: Helical filament]]
		+	[[Category: Protein disaggregase]]
		+	[[Category: Two-ring aaa protein]]

OCA at 05:05, 18 July 2018

OCA — Wed, 18 Jul 2018 05:05:40 GMT

←Older revision		Revision as of 05:05, 18 July 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zui is ON HOLD	+	The entry 5zui is ON HOLD until Paper Publication

	Authors: Hanazono, Y., Inoue, Y., Noguchi, K., Yohda, M., Shinohara, K., Takeda, K., Miki, K.		Authors: Hanazono, Y., Inoue, Y., Noguchi, K., Yohda, M., Shinohara, K., Takeda, K., Miki, K.
Line 9:		Line 9:
	[[Category: Takeda, K]]		[[Category: Takeda, K]]
	[[Category: Noguchi, K]]		[[Category: Noguchi, K]]
-	[[Category: Shinohara, K]]
-	[[Category: Yohda, M]]
	[[Category: Inoue, Y]]		[[Category: Inoue, Y]]
	[[Category: Hanazono, Y]]		[[Category: Hanazono, Y]]
		+	[[Category: Shinohara, K]]
	[[Category: Miki, K]]		[[Category: Miki, K]]
		+	[[Category: Yohda, M]]

OCA: Protected "5zui" [edit=sysop:move=sysop]

OCA — Wed, 16 May 2018 03:53:34 GMT

Protected "5zui" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:53, 16 May 2018

OCA: New page: '''Unreleased structure''' The entry 5zui is ON HOLD Authors: Hanazono, Y., Inoue, Y., Noguchi, K., Yohda, M., Shinohara, K., Takeda, K., Miki, K. Description: Crystal Structure of HSP...

OCA — Wed, 16 May 2018 03:53:33 GMT

New page: '''Unreleased structure''' The entry 5zui is ON HOLD Authors: Hanazono, Y., Inoue, Y., Noguchi, K., Yohda, M., Shinohara, K., Takeda, K., Miki, K. Description: Crystal Structure of HSP...

New page

'''Unreleased structure'''

The entry 5zui is ON HOLD

Authors: Hanazono, Y., Inoue, Y., Noguchi, K., Yohda, M., Shinohara, K., Takeda, K., Miki, K.

Description: Crystal Structure of HSP104 from Chaetomium thermophilum
[[Category: Unreleased Structures]]
[[Category: Takeda, K]]
[[Category: Noguchi, K]]
[[Category: Shinohara, K]]
[[Category: Yohda, M]]
[[Category: Inoue, Y]]
[[Category: Hanazono, Y]]
[[Category: Miki, K]]