5zvv - Revision history

OCA at 12:34, 13 March 2019

OCA — Wed, 13 Mar 2019 12:34:37 GMT

←Older revision		Revision as of 12:34, 13 March 2019
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	==Structure of SeMet-phAimR==		==Structure of SeMet-phAimR==
-	<StructureSection load='5zvv' size='340' side='right' caption='[[5zvv]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='5zvv' size='340' side='right'caption='[[5zvv]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zvv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZVV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zvv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bppht Bppht]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZVV FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aimR, phi3T_89 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10736 BPPHT])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zvv OCA], [http://pdbe.org/5zvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zvv RCSB], [http://www.ebi.ac.uk/pdbsum/5zvv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zvv ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zvv OCA], [http://pdbe.org/5zvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zvv RCSB], [http://www.ebi.ac.uk/pdbsum/5zvv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zvv ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Communication is vital for all organisms including microorganisms, which is clearly demonstrated by the bacterial quorum-sensing system. However, the molecular mechanisms underlying communication among viruses (phages) via the quorum-sensing-like 'arbitrium' system remain unclear. Viral or host densities are known to be related to an increased prevalence of lysogeny; however, how the switch from the lytic to the lysogenic pathway occurs is unknown. Thus, we sought to reveal mechanisms of communication among viruses and determine the lysogenic dynamics involved. Structural and functional analyses of the phage-derived SAIRGA and GMPRGA peptides and their corresponding receptors, phAimR and spAimR, indicated that SAIRGA directs the lysis-lysogeny decision of phi3T by modulating conformational changes in phAimR, whereas GMPRGA regulates the lysis-lysogeny pathway by stabilizing spAimR in the dimeric state. Although temperate viruses are thought to share a similar lytic-lysogenic cycle switch model, our study suggests the existence of alternative strain-specific mechanisms that regulate the lysis-lysogeny decision. Collectively, these findings provide insights into the molecular mechanisms underlying communication among viruses, offering theoretical applications for the treatment of infectious viral diseases.
		+
		+	Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities.,Dou C, Xiong J, Gu Y, Yin K, Wang J, Hu Y, Zhou D, Fu X, Qi S, Zhu X, Yao S, Xu H, Nie C, Liang Z, Yang S, Wei Y, Cheng W Nat Microbiol. 2018 Nov;3(11):1285-1294. doi: 10.1038/s41564-018-0259-7. Epub, 2018 Oct 15. PMID:30323253<ref>PMID:30323253</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5zvv" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chao~~, D]]	+	[[Category: Bppht]]
-	[[Category: ~~Wei~~, C]]	+	[[Category: Large Structures]]
		+	[[Category: Cheng, W]]
		+	[[Category: Dou, C]]
	[[Category: Dimer]]		[[Category: Dimer]]
	[[Category: Phage phi3t]]		[[Category: Phage phi3t]]
	[[Category: Transcription regulator]]		[[Category: Transcription regulator]]

OCA at 10:02, 5 September 2018

OCA — Wed, 05 Sep 2018 10:02:31 GMT

←Older revision		Revision as of 10:02, 5 September 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 5zvv is ~~ON HOLD until Paper Publication~~	+	==Structure of SeMet-phAimR==
-		+	<StructureSection load='5zvv' size='340' side='right' caption='[[5zvv]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~Authors~~: ~~Wei~~, C., ~~Chao~~, D.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5zvv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZVV FirstGlance]. <br>
-	~~Description~~: ~~Structure of SeMet~~-~~phAimR~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zvv OCA], [http://pdbe.org/5zvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zvv RCSB], [http://www.ebi.ac.uk/pdbsum/5zvv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zvv ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chao, D]]
	[[Category: Wei, C]]		[[Category: Wei, C]]
-	[[Category: ~~Chao, D~~]]	+	[[Category: Dimer]]
		+	[[Category: Phage phi3t]]
		+	[[Category: Transcription regulator]]

OCA at 05:29, 29 August 2018

OCA — Wed, 29 Aug 2018 05:29:11 GMT

←Older revision		Revision as of 05:29, 29 August 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zvv is ON HOLD	+	The entry 5zvv is ON HOLD until Paper Publication

	Authors: Wei, C., Chao, D.		Authors: Wei, C., Chao, D.
Line 7:		Line 7:
	Description: Structure of SeMet-phAimR		Description: Structure of SeMet-phAimR
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Chao, D]]
	[[Category: Wei, C]]		[[Category: Wei, C]]
		+	[[Category: Chao, D]]

OCA at 03:52, 30 May 2018

OCA — Wed, 30 May 2018 03:52:28 GMT

←Older revision		Revision as of 03:52, 30 May 2018
Line 5:		Line 5:
	Authors: Wei, C., Chao, D.		Authors: Wei, C., Chao, D.

-	Description: SeMet-phAimR	+	Description: Structure of SeMet-phAimR
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Chao, D]]		[[Category: Chao, D]]
	[[Category: Wei, C]]		[[Category: Wei, C]]

OCA: Protected "5zvv" [edit=sysop:move=sysop]

OCA — Wed, 23 May 2018 05:50:57 GMT

Protected "5zvv" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:50, 23 May 2018

OCA: New page: '''Unreleased structure''' The entry 5zvv is ON HOLD Authors: Wei, C., Chao, D. Description: SeMet-phAimR Category: Unreleased Structures Category: Chao, D Category: Wei, C

OCA — Wed, 23 May 2018 05:50:56 GMT

New page: '''Unreleased structure''' The entry 5zvv is ON HOLD Authors: Wei, C., Chao, D. Description: SeMet-phAimR Category: Unreleased Structures Category: Chao, D Category: Wei, C

New page

'''Unreleased structure'''

The entry 5zvv is ON HOLD

Authors: Wei, C., Chao, D.

Description: SeMet-phAimR
[[Category: Unreleased Structures]]
[[Category: Chao, D]]
[[Category: Wei, C]]