5zx1 - Revision history

OCA at 09:09, 22 November 2023

OCA — Wed, 22 Nov 2023 09:09:51 GMT

←Older revision		Revision as of 09:09, 22 November 2023
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	<StructureSection load='5zx1' size='340' side='right'caption='[[5zx1]], [[Resolution\|resolution]] 2.31Å' scene=''>		<StructureSection load='5zx1' size='340' side='right'caption='[[5zx1]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zx1]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Tryb2 Tryb2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5ZX1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zx1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZX1 FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~Tb11.02.2890 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=185431 TRYB2])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.31Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5zx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zx1 OCA], [~~http~~://pdbe.org/5zx1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5zx1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5zx1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5zx1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zx1 OCA], [https://pdbe.org/5zx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zx1 RCSB], [https://www.ebi.ac.uk/pdbsum/5zx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zx1 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q385P5_TRYB2 Q385P5_TRYB2]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Trypanosoma brucei (T. brucei) is a parasitic protozoan causing human sleeping sickness and related animal diseases. ENT (EMSY N-terminal) domain was first found in EMSY protein which has been proved to be involved in multiple biological processes such as DNA repair, tumorigenesis, and transcriptional regulation. So far, little is known about the function and structure of ENT domains from protozoan. Q385P5 from T. brucei, containing an ENT domain at its N-terminus, is a conserved protein in related kinetoplastid parasites. In this work, the crystal structure of ENT domain of Q385P5 (TbENT) was solved at a resolution of 2.3â¯A. TbENT adopts a club-like shape consisting of five helixes, which is similar to the structure of human EMSY ENT domain (HsENT). Interestingly, TbENT shows significantly different orientation on the fifth alpha-helix compared with HsENT. Meanwhile, human HP1 interacts with a conserved motif adjacent to EMSY ENT domain. However, this conserved binding motif is absent in Q385P5. These differences may imply the different protein interactions and roles of Q385P5 and its ENT domain in T. brucei.
		+
		+	Crystal structure of an ENT domain from Trypanosoma brucei.,Mi J, Yang X, Zhang J, Zhang X, Xu C, Liao S, Tu X Biochem Biophys Res Commun. 2018 Nov 2;505(3):755-760. doi: , 10.1016/j.bbrc.2018.09.167. Epub 2018 Oct 4. PMID:30293681<ref>PMID:30293681</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5zx1" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Tryb2~~]]	+	[[Category: Trypanosoma brucei brucei TREU927]]
-	[[Category: Juan, M]]	+	[[Category: Juan M]]
-	[[Category: Shanhui, L]]	+	[[Category: Shanhui L]]
-	[[Category: Xiaoming, T]]	+	[[Category: Xiaoming T]]
-	~~[[Category: Ent domain]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 08:00, 2 December 2020

OCA — Wed, 02 Dec 2020 08:00:32 GMT

←Older revision		Revision as of 08:00, 2 December 2020
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	<StructureSection load='5zx1' size='340' side='right'caption='[[5zx1]], [[Resolution\|resolution]] 2.31Å' scene=''>		<StructureSection load='5zx1' size='340' side='right'caption='[[5zx1]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zx1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX1 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ZX1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zx1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tryb2 Tryb2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ZX1 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5zx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zx1 OCA], [http://pdbe.org/5zx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zx1 RCSB], [http://www.ebi.ac.uk/pdbsum/5zx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zx1 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tb11.02.2890 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=185431 TRYB2])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5zx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zx1 OCA], [http://pdbe.org/5zx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zx1 RCSB], [http://www.ebi.ac.uk/pdbsum/5zx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zx1 ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Tryb2]]
	[[Category: Juan, M]]		[[Category: Juan, M]]
	[[Category: Shanhui, L]]		[[Category: Shanhui, L]]

OCA at 06:41, 23 May 2019

OCA — Thu, 23 May 2019 06:41:52 GMT

←Older revision		Revision as of 06:41, 23 May 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 5zx1 is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of ENT domain from T. brucei==
-		+	<StructureSection load='5zx1' size='340' side='right'caption='[[5zx1]], [[Resolution\|resolution]] 2.31Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5zx1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZX1 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zx1 OCA], [http://pdbe.org/5zx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zx1 RCSB], [http://www.ebi.ac.uk/pdbsum/5zx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zx1 ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Juan, M]]
		+	[[Category: Shanhui, L]]
		+	[[Category: Xiaoming, T]]
		+	[[Category: Ent domain]]
		+	[[Category: Transcription]]

OCA at 05:52, 12 September 2018

OCA — Wed, 12 Sep 2018 05:52:49 GMT

←Older revision		Revision as of 05:52, 12 September 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zx1 is ON HOLD	+	The entry 5zx1 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5zx1" [edit=sysop:move=sysop]

OCA — Wed, 23 May 2018 05:54:25 GMT

Protected "5zx1" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:54, 23 May 2018

OCA: New page: '''Unreleased structure''' The entry 5zx1 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 23 May 2018 05:54:24 GMT

New page: '''Unreleased structure''' The entry 5zx1 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5zx1 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]