5zxe - Revision history

OCA at 09:09, 22 November 2023

OCA — Wed, 22 Nov 2023 09:09:56 GMT

←Older revision		Revision as of 09:09, 22 November 2023
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	<StructureSection load='5zxe' size='340' side='right'caption='[[5zxe]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='5zxe' size='340' side='right'caption='[[5zxe]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zxe]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZXE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ZXE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zxe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZXE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZXE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.3Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5zxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zxe OCA], [~~http~~://pdbe.org/5zxe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5zxe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5zxe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5zxe ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zxe OCA], [https://pdbe.org/5zxe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zxe RCSB], [https://www.ebi.ac.uk/pdbsum/5zxe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zxe ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation. The FGF signal pathways are the RAS/MAP kinase pathway, PI3 kinase/AKT pathway, and PLCgamma pathway, among which the RAS/MAP kinase pathway is known to be predominant. Several studies have recently implicated the in vitro biological functions of FGFs for tissue regeneration. However, to obtain optimal outcomes in vivo, it is important to enhance the half-life of FGFs and their biological stability. Future applications of FGFs are expected when the biological functions of FGFs are potentiated through the appropriate use of delivery systems and scaffolds. This review will introduce the biology and cellular functions of FGFs and deal with the biomaterials based delivery systems and their current applications for the regeneration of tissues, including skin, blood vessel, muscle, adipose, tendon/ligament, cartilage, bone, tooth, and nerve tissues.
-
-	Fibroblast growth factors: biology, function, and application for tissue regeneration.,Yun YR, Won JE, Jeon E, Lee S, Kang W, Jo H, Jang JH, Shin US, Kim HW J Tissue Eng. 2010 Nov 7;2010:218142. doi: 10.4061/2010/218142. PMID:21350642<ref>PMID:21350642</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5zxe" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gosavi, S]]	+	[[Category: Gosavi S]]
-	[[Category: Mandalaparthy, V]]	+	[[Category: Mandalaparthy V]]
-	[[Category: Ramaswamy, S]]	+	[[Category: Ramaswamy S]]
-	[[Category: Tripathi~~, S K]]~~	+	[[Category: Tripathi SK]]
-	~~[[Category: Basic form]]~~	+
-	~~[[Category: Cell cycle]]~~	+
-	~~[[Category: Fgf~~]]	+

OCA at 16:30, 22 January 2020

OCA — Wed, 22 Jan 2020 16:30:27 GMT

←Older revision		Revision as of 16:30, 22 January 2020
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	<StructureSection load='5zxe' size='340' side='right'caption='[[5zxe]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='5zxe' size='340' side='right'caption='[[5zxe]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zxe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZXE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zxe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZXE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zxe OCA], [http://pdbe.org/5zxe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zxe RCSB], [http://www.ebi.ac.uk/pdbsum/5zxe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zxe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zxe OCA], [http://pdbe.org/5zxe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zxe RCSB], [http://www.ebi.ac.uk/pdbsum/5zxe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zxe ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Gosavi, S]]		[[Category: Gosavi, S]]

OCA at 06:04, 24 July 2019

OCA — Wed, 24 Jul 2019 06:04:49 GMT

←Older revision		Revision as of 06:04, 24 July 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5zxe is ~~ON HOLD until Paper~~ Publication	+	==Structure of a consensus sequence derived from the FGF family==
		+	<StructureSection load='5zxe' size='340' side='right'caption='[[5zxe]], [[Resolution\|resolution]] 1.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5zxe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZXE FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zxe OCA], [http://pdbe.org/5zxe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zxe RCSB], [http://www.ebi.ac.uk/pdbsum/5zxe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zxe ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation. The FGF signal pathways are the RAS/MAP kinase pathway, PI3 kinase/AKT pathway, and PLCgamma pathway, among which the RAS/MAP kinase pathway is known to be predominant. Several studies have recently implicated the in vitro biological functions of FGFs for tissue regeneration. However, to obtain optimal outcomes in vivo, it is important to enhance the half-life of FGFs and their biological stability. Future applications of FGFs are expected when the biological functions of FGFs are potentiated through the appropriate use of delivery systems and scaffolds. This review will introduce the biology and cellular functions of FGFs and deal with the biomaterials based delivery systems and their current applications for the regeneration of tissues, including skin, blood vessel, muscle, adipose, tendon/ligament, cartilage, bone, tooth, and nerve tissues.

-	~~Authors~~: ~~Tripathi~~, ~~S.K~~., ~~Mandalaparthy~~, V., ~~Ramaswamy~~, S., ~~Gosavi~~, S.	+	Fibroblast growth factors: biology, function, and application for tissue regeneration.,Yun YR, Won JE, Jeon E, Lee S, Kang W, Jo H, Jang JH, Shin US, Kim HW J Tissue Eng. 2010 Nov 7;2010:218142. doi: 10.4061/2010/218142. PMID:21350642<ref>PMID:21350642</ref>

-	~~Description: Structure of~~ a ~~consensus sequence derived from~~ the ~~FGF family~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 5zxe" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Gosavi, S]]		[[Category: Gosavi, S]]
-	[[Category: Ramaswamy, S]]
-	[[Category: Tripathi, S.K]]
	[[Category: Mandalaparthy, V]]		[[Category: Mandalaparthy, V]]
		+	[[Category: Ramaswamy, S]]
		+	[[Category: Tripathi, S K]]
		+	[[Category: Basic form]]
		+	[[Category: Cell cycle]]
		+	[[Category: Fgf]]

OCA at 08:37, 17 July 2019

OCA — Wed, 17 Jul 2019 08:37:16 GMT

←Older revision		Revision as of 08:37, 17 July 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zxe is ON HOLD	+	The entry 5zxe is ON HOLD until Paper Publication

	Authors: Tripathi, S.K., Mandalaparthy, V., Ramaswamy, S., Gosavi, S.		Authors: Tripathi, S.K., Mandalaparthy, V., Ramaswamy, S., Gosavi, S.
Line 7:		Line 7:
	Description: Structure of a consensus sequence derived from the FGF family		Description: Structure of a consensus sequence derived from the FGF family
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Gosavi, S]]
	[[Category: Ramaswamy, S]]		[[Category: Ramaswamy, S]]
	[[Category: Tripathi, S.K]]		[[Category: Tripathi, S.K]]
-	[[Category: Gosavi, S]]
	[[Category: Mandalaparthy, V]]		[[Category: Mandalaparthy, V]]

OCA at 03:55, 10 July 2019

OCA — Wed, 10 Jul 2019 03:55:27 GMT

←Older revision		Revision as of 03:55, 10 July 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zxe is ON HOLD ~~until Jul 19 2020~~	+	The entry 5zxe is ON HOLD

	Authors: Tripathi, S.K., Mandalaparthy, V., Ramaswamy, S., Gosavi, S.		Authors: Tripathi, S.K., Mandalaparthy, V., Ramaswamy, S., Gosavi, S.

OCA at 04:58, 26 June 2019

OCA — Wed, 26 Jun 2019 04:58:02 GMT

←Older revision		Revision as of 04:58, 26 June 2019
Line 3:		Line 3:
	The entry 5zxe is ON HOLD until Jul 19 2020		The entry 5zxe is ON HOLD until Jul 19 2020

-	Authors: Tripathi, S.K., Mandalaparthy, V., Gosavi, S.	+	Authors: Tripathi, S.K., Mandalaparthy, V., Ramaswamy, S., Gosavi, S.

	Description: Structure of a consensus sequence derived from the FGF family		Description: Structure of a consensus sequence derived from the FGF family
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Ramaswamy, S]]
	[[Category: Tripathi, S.K]]		[[Category: Tripathi, S.K]]
	[[Category: Gosavi, S]]		[[Category: Gosavi, S]]
	[[Category: Mandalaparthy, V]]		[[Category: Mandalaparthy, V]]

OCA at 05:15, 10 April 2019

OCA — Wed, 10 Apr 2019 05:15:46 GMT

←Older revision		Revision as of 05:15, 10 April 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zxe is ON HOLD until ~~Paper Publication~~	+	The entry 5zxe is ON HOLD until Jul 19 2020

	Authors: Tripathi, S.K., Mandalaparthy, V., Gosavi, S.		Authors: Tripathi, S.K., Mandalaparthy, V., Gosavi, S.

OCA at 05:22, 14 June 2018

OCA — Thu, 14 Jun 2018 05:22:06 GMT

←Older revision		Revision as of 05:22, 14 June 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zxe is ON HOLD	+	The entry 5zxe is ON HOLD until Paper Publication

	Authors: Tripathi, S.K., Mandalaparthy, V., Gosavi, S.		Authors: Tripathi, S.K., Mandalaparthy, V., Gosavi, S.

OCA: Protected "5zxe" [edit=sysop:move=sysop]

OCA — Wed, 30 May 2018 03:53:13 GMT

Protected "5zxe" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:53, 30 May 2018

OCA: New page: '''Unreleased structure''' The entry 5zxe is ON HOLD Authors: Tripathi, S.K., Mandalaparthy, V., Gosavi, S. Description: Structure of a consensus sequence derived from the FGF family [...

OCA — Wed, 30 May 2018 03:53:12 GMT

New page: '''Unreleased structure''' The entry 5zxe is ON HOLD Authors: Tripathi, S.K., Mandalaparthy, V., Gosavi, S. Description: Structure of a consensus sequence derived from the FGF family [...

New page

'''Unreleased structure'''

The entry 5zxe is ON HOLD

Authors: Tripathi, S.K., Mandalaparthy, V., Gosavi, S.

Description: Structure of a consensus sequence derived from the FGF family
[[Category: Unreleased Structures]]
[[Category: Tripathi, S.K]]
[[Category: Gosavi, S]]
[[Category: Mandalaparthy, V]]