5zyi - Revision history

OCA at 10:29, 27 March 2024

OCA — Wed, 27 Mar 2024 10:29:44 GMT

←Older revision		Revision as of 10:29, 27 March 2024
Line 1:		Line 1:

	==Crystal structure of CERT START domain in complex with compound E16==		==Crystal structure of CERT START domain in complex with compound E16==
-	<StructureSection load='5zyi' size='340' side='right' caption='[[5zyi]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5zyi' size='340' side='right'caption='[[5zyi]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zyi]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ZYI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zyi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZYI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9ML:2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9ML</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CERT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9ML:2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9ML</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zyi OCA], [~~http~~://pdbe.org/5zyi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5zyi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5zyi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5zyi ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zyi OCA], [https://pdbe.org/5zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zyi RCSB], [https://www.ebi.ac.uk/pdbsum/5zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zyi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~C43BP_HUMAN C43BP_HUMAN]~~] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>	+	[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Egawa, D]]	+	[[Category: Large Structures]]
-	[[Category: Hanada, K]]	+	[[Category: Egawa D]]
-	[[Category: Hanzawa, H]]	+	[[Category: Hanada K]]
-	[[Category: Kawasaki, S]]	+	[[Category: Hanzawa H]]
-	[[Category: Kobayashi, S]]	+	[[Category: Kawasaki S]]
-	[[Category: Kumagai, K]]	+	[[Category: Kobayashi S]]
-	[[Category: Nakao, N]]	+	[[Category: Kumagai K]]
-	[[Category: Sakai, S]]	+	[[Category: Nakao N]]
-	[[Category: Suzuki, M]]	+	[[Category: Sakai S]]
-	[[Category: Ueno, M]]	+	[[Category: Suzuki M]]
-	~~[[Category: Cert]]~~	+	[[Category: Ueno M]]
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Lipid transport]]~~	+
-	~~[[Category: Ph]]~~	+
-	~~[[Category: Start~~]]	+

OCA at 08:18, 6 March 2019

OCA — Wed, 06 Mar 2019 08:18:36 GMT

←Older revision		Revision as of 08:18, 6 March 2019
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	==Crystal structure of CERT START domain in complex with compound E16==		==Crystal structure of CERT START domain in complex with compound E16==
-	<StructureSection load='5zyi' size='340' side='right' caption='[[5zyi]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5zyi' size='340' side='right' caption='[[5zyi]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5zyi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZYI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5zyi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZYI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9ML:2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9ML</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9ML:2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9ML</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CERT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zyi OCA], [http://pdbe.org/5zyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zyi RCSB], [http://www.ebi.ac.uk/pdbsum/5zyi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zyi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zyi OCA], [http://pdbe.org/5zyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zyi RCSB], [http://www.ebi.ac.uk/pdbsum/5zyi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zyi ProSAT]</span></td></tr>
	</table>		</table>
Line 13:		Line 14:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Egawa, D]]		[[Category: Egawa, D]]
	[[Category: Hanada, K]]		[[Category: Hanada, K]]

OCA at 15:13, 27 February 2019

OCA — Wed, 27 Feb 2019 15:13:23 GMT

←Older revision		Revision as of 15:13, 27 February 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5zyi ~~is ON HOLD until Paper Publication~~	+	==Crystal structure of CERT START domain in complex with compound E16==
-		+	<StructureSection load='5zyi' size='340' side='right' caption='[[5zyi]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~Authors~~: ~~Suzuki, M~~.~~, Nakao, N~~.~~, Ueno, M~~.~~, Sakai, S~~., ~~Egawa, D~~., ~~Hanzawa, H~~., ~~Kawasaki, S~~., ~~Kumagai, K~~., ~~Kobayashi, S~~., ~~Hanada, K~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5zyi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZYI FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of CERT~~ START domain in ~~complex with compound E16~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9ML:2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9ML</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zyi OCA], [http://pdbe.org/5zyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zyi RCSB], [http://www.ebi.ac.uk/pdbsum/5zyi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zyi ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/C43BP_HUMAN C43BP_HUMAN]] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Egawa, D]]
		+	[[Category: Hanada, K]]
		+	[[Category: Hanzawa, H]]
		+	[[Category: Kawasaki, S]]
	[[Category: Kobayashi, S]]		[[Category: Kobayashi, S]]
-	[[Category: Hanada, K]]
-	[[Category: Suzuki, M]]
	[[Category: Kumagai, K]]		[[Category: Kumagai, K]]
		+	[[Category: Nakao, N]]
	[[Category: Sakai, S]]		[[Category: Sakai, S]]
-	[[Category: ~~Nakao~~, ~~N]]~~	+	[[Category: Suzuki, M]]
-	~~[[Category: Egawa, D]]~~	+
-	~~[[Category: Kawasaki, S]]~~	+
-	~~[[Category: Hanzawa, H~~]]	+
	[[Category: Ueno, M]]		[[Category: Ueno, M]]
		+	[[Category: Cert]]
		+	[[Category: Complex]]
		+	[[Category: Lipid transport]]
		+	[[Category: Ph]]
		+	[[Category: Start]]

OCA at 05:22, 14 June 2018

OCA — Thu, 14 Jun 2018 05:22:30 GMT

←Older revision		Revision as of 05:22, 14 June 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5zyi is ON HOLD	+	The entry 5zyi is ON HOLD until Paper Publication

	Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.		Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.

OCA: Protected "5zyi" [edit=sysop:move=sysop]

OCA — Wed, 30 May 2018 03:57:04 GMT

Protected "5zyi" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:57, 30 May 2018

OCA: New page: '''Unreleased structure''' The entry 5zyi is ON HOLD Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K. D...

OCA — Wed, 30 May 2018 03:57:02 GMT

New page: '''Unreleased structure''' The entry 5zyi is ON HOLD Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K. D...

New page

'''Unreleased structure'''

The entry 5zyi is ON HOLD

Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.

Description: Crystal structure of CERT START domain in complex with compound E16
[[Category: Unreleased Structures]]
[[Category: Kobayashi, S]]
[[Category: Hanada, K]]
[[Category: Suzuki, M]]
[[Category: Kumagai, K]]
[[Category: Sakai, S]]
[[Category: Nakao, N]]
[[Category: Egawa, D]]
[[Category: Kawasaki, S]]
[[Category: Hanzawa, H]]
[[Category: Ueno, M]]