6aio - Revision history

OCA at 09:31, 22 November 2023

OCA — Wed, 22 Nov 2023 09:31:49 GMT

←Older revision		Revision as of 09:31, 22 November 2023
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	<StructureSection load='6aio' size='340' side='right'caption='[[6aio]], [[Resolution\|resolution]] 2.04Å' scene=''>		<StructureSection load='6aio' size='340' side='right'caption='[[6aio]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6aio]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AIO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6AIO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6aio]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AIO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6aio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aio OCA], [~~http~~://pdbe.org/6aio PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6aio RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6aio PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6aio ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.04Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6aio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aio OCA], [https://pdbe.org/6aio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6aio RCSB], [https://www.ebi.ac.uk/pdbsum/6aio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6aio ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/C6FI48_PSEPU C6FI48_PSEPU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen~~, Q Z~~]]	+	[[Category: Pseudomonas putida]]
-	[[Category: Cui~~, Z L~~]]	+	[[Category: Chen QZ]]
-	[[Category: Duan~~, Y J~~]]	+	[[Category: Cui ZL]]
-	[[Category: Huang, Y]]	+	[[Category: Duan YJ]]
-	[[Category: Li~~, Z K~~]]	+	[[Category: Huang Y]]
-	[[Category: Liu~~, W D]]~~	+	[[Category: Li ZK]]
-	~~[[Category: Flavoprotein]]~~	+	[[Category: Liu WD]]
-	~~[[Category: P-nitrophenol 4-monooxygenase~~]]	+

OCA at 21:28, 28 October 2020

OCA — Wed, 28 Oct 2020 21:28:40 GMT

←Older revision		Revision as of 21:28, 28 October 2020
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	==Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4==		==Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4==
-	<StructureSection load='6aio' size='340' side='right' caption='[[6aio]], [[Resolution\|resolution]] 2.04Å' scene=''>	+	<StructureSection load='6aio' size='340' side='right'caption='[[6aio]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6aio]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AIO OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6AIO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6aio]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AIO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6AIO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6aio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aio OCA], [http://pdbe.org/6aio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aio RCSB], [http://www.ebi.ac.uk/pdbsum/6aio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aio ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6aio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aio OCA], [http://pdbe.org/6aio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aio RCSB], [http://www.ebi.ac.uk/pdbsum/6aio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aio ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Chen, Q Z]]		[[Category: Chen, Q Z]]
	[[Category: Cui, Z L]]		[[Category: Cui, Z L]]

OCA at 06:46, 31 October 2018

OCA — Wed, 31 Oct 2018 06:46:58 GMT

←Older revision		Revision as of 06:46, 31 October 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6aio is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4==
		+	<StructureSection load='6aio' size='340' side='right' caption='[[6aio]], [[Resolution\|resolution]] 2.04Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6aio]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AIO FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aio OCA], [http://pdbe.org/6aio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aio RCSB], [http://www.ebi.ac.uk/pdbsum/6aio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aio ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	p-Nitrophenol 4-monooxygenase PnpA, the key enzyme in the hydroquinone pathway of p-nitrophenol (PNP) degradation, catalyzes the monooxygenase reaction of PNP to p-benzoquinone in the presence of FAD and NADH. Here, we determined the first crystal structure of PnpA from Pseudomonas putida DLL-E4 in its apo and FAD-complex forms to a resolution of 2.04A and 2.48A, respectively. The PnpA structure shares a common fold with hydroxybenzoate hydroxylases, despite a low amino sequence identity of 14-18%, confirming it to be a member of the Class A flavoprotein monooxygenases. However, substrate docking studies of PnpA indicated that the residues stabilizing the substrate in an orientation suitable for catalysis are not observed in other homologous hydroxybenzoate hydroxylases, suggesting PnpA employs a unique catalytic mechanism. This work expands our understanding on the reaction mode for this enzyme class.

-	~~Authors~~: Chen, Q~~.Z.~~, Huang, Y., Duan, Y~~.J.~~, Li, Z~~.K.~~, Liu, W.D., ~~Cui, Z~~.L.	+	Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4: The key enzyme involved in p-nitrophenol degradation.,Chen Q, Huang Y, Duan Y, Li Z, Cui Z, Liu W Biochem Biophys Res Commun. 2018 Oct 12;504(4):715-720. doi:, 10.1016/j.bbrc.2018.09.040. Epub 2018 Sep 12. PMID:30217456<ref>PMID:30217456</ref>

-	~~Description: Crystal structure~~ of p-~~nitrophenol 4~~-~~monooxygenase PnpA from Pseudomonas putida DLL-E4~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
-	[[Category: Li, Z~~.K]]~~	+	<div class="pdbe-citations 6aio" style="background-color:#fffaf0;"></div>
-	~~[[Category: Duan, Y.J~~]]	+	== References ==
-	[[Category: Cui, Z.L]]	+	<references/>
-	[[Category: ~~Liu~~, ~~W.D~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Chen, Q Z]]
		+	[[Category: Cui, Z L]]
		+	[[Category: Duan, Y J]]
	[[Category: Huang, Y]]		[[Category: Huang, Y]]
-	[[Category: ~~Chen~~, Q.Z]]	+	[[Category: Li, Z K]]
		+	[[Category: Liu, W D]]
		+	[[Category: Flavoprotein]]
		+	[[Category: P-nitrophenol 4-monooxygenase]]

OCA at 05:54, 12 September 2018

OCA — Wed, 12 Sep 2018 05:54:24 GMT

←Older revision		Revision as of 05:54, 12 September 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6aio is ON HOLD	+	The entry 6aio is ON HOLD until Paper Publication

	Authors: Chen, Q.Z., Huang, Y., Duan, Y.J., Li, Z.K., Liu, W.D., Cui, Z.L.		Authors: Chen, Q.Z., Huang, Y., Duan, Y.J., Li, Z.K., Liu, W.D., Cui, Z.L.

OCA: Protected "6aio" [edit=sysop:move=sysop]

OCA — Wed, 29 Aug 2018 05:36:38 GMT

Protected "6aio" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:36, 29 August 2018

OCA: New page: '''Unreleased structure''' The entry 6aio is ON HOLD Authors: Chen, Q.Z., Huang, Y., Duan, Y.J., Li, Z.K., Liu, W.D., Cui, Z.L. Description: Crystal structure of p-nitrophenol 4-monoox...

OCA — Wed, 29 Aug 2018 05:36:36 GMT

New page: '''Unreleased structure''' The entry 6aio is ON HOLD Authors: Chen, Q.Z., Huang, Y., Duan, Y.J., Li, Z.K., Liu, W.D., Cui, Z.L. Description: Crystal structure of p-nitrophenol 4-monoox...

New page

'''Unreleased structure'''

The entry 6aio is ON HOLD

Authors: Chen, Q.Z., Huang, Y., Duan, Y.J., Li, Z.K., Liu, W.D., Cui, Z.L.

Description: Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4
[[Category: Unreleased Structures]]
[[Category: Li, Z.K]]
[[Category: Duan, Y.J]]
[[Category: Cui, Z.L]]
[[Category: Liu, W.D]]
[[Category: Huang, Y]]
[[Category: Chen, Q.Z]]