6alk - Revision history

OCA at 10:37, 14 June 2023

OCA — Wed, 14 Jun 2023 10:37:06 GMT

←Older revision		Revision as of 10:37, 14 June 2023
Line 1:		Line 1:

	==NMR solution structure of the major beech pollen allergen Fag s 1==		==NMR solution structure of the major beech pollen allergen Fag s 1==
-	<StructureSection load='6alk' size='340' side='right'caption='[[6alk~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='6alk' size='340' side='right'caption='[[6alk]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Beechnut Beechnut~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ALK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fagus_sylvatica Fagus sylvatica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ALK FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6alk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6alk OCA], [~~http~~://pdbe.org/6alk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6alk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6alk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6alk ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6alk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6alk OCA], [https://pdbe.org/6alk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6alk RCSB], [https://www.ebi.ac.uk/pdbsum/6alk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6alk ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B7TWE6_FAGSY B7TWE6_FAGSY]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Beechnut~~]]	+	[[Category: Fagus sylvatica]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Almeida~~, F C.L~~]]	+	[[Category: Almeida FCL]]
-	[[Category: Asam, A]]	+	[[Category: Asam A]]
-	[[Category: Ferreira, F]]	+	[[Category: Ferreira F]]
-	[[Category: Moraes~~, A H~~]]	+	[[Category: Moraes AH]]
-	[[Category: Valente~~, A P~~]]	+	[[Category: Valente AP]]
-	[[Category: Wallner, M]]	+	[[Category: Wallner M]]
-	~~[[Category: Allergen]]~~	+
-	~~[[Category: Conformational diversity]]~~	+
-	~~[[Category: Ligand binding~~]]	+

OCA at 06:35, 17 April 2019

OCA — Wed, 17 Apr 2019 06:35:16 GMT

←Older revision		Revision as of 06:35, 17 April 2019
Line 1:		Line 1:

	==NMR solution structure of the major beech pollen allergen Fag s 1==		==NMR solution structure of the major beech pollen allergen Fag s 1==
-	<StructureSection load='6alk' size='340' side='right' caption='[[6alk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='6alk' size='340' side='right'caption='[[6alk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beechnut Beechnut]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ALK FirstGlance]. <br>		<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beechnut Beechnut]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ALK FirstGlance]. <br>
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Beechnut]]		[[Category: Beechnut]]
		+	[[Category: Large Structures]]
	[[Category: Almeida, F C.L]]		[[Category: Almeida, F C.L]]
	[[Category: Asam, A]]		[[Category: Asam, A]]

OCA at 15:53, 27 February 2019

OCA — Wed, 27 Feb 2019 15:53:56 GMT

←Older revision		Revision as of 15:53, 27 February 2019
Line 3:		Line 3:
	<StructureSection load='6alk' size='340' side='right' caption='[[6alk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='6alk' size='340' side='right' caption='[[6alk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ALK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beechnut Beechnut]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ALK FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6alk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6alk OCA], [http://pdbe.org/6alk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6alk RCSB], [http://www.ebi.ac.uk/pdbsum/6alk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6alk ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6alk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6alk OCA], [http://pdbe.org/6alk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6alk RCSB], [http://www.ebi.ac.uk/pdbsum/6alk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6alk ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fag s 1 is a member of the Pathogen Related protein family 10 (PR-10) and can elicit cross-reaction with IgE antibodies produced against the birch pollen allergen Bet v 1. The Nuclear Magnetic Resonance (NMR) structure of Fag s 1 is presented along with its dynamic properties. It shares 66% identity with Bet v 1 and exhibits the expected three alpha-helices and seven beta-sheets arranged as a semi-beta barrel and exposing the residues mapped as the Bet v 1 IgE epitope. The structural dynamics of Fag s 1 were monitored on the fast and intermediate timescales, using relaxation rates. The complex dynamics of Fag s 1 are closely related to the internal cavity, and they modulate IgE and ligand binding.
		+
		+	Structural basis for cross-reactivity and conformation fluctuation of the major beech pollen allergen Fag s 1.,Moraes AH, Asam C, Almeida FCL, Wallner M, Ferreira F, Valente AP Sci Rep. 2018 Jul 12;8(1):10512. doi: 10.1038/s41598-018-28358-1. PMID:30002383<ref>PMID:30002383</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6alk" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Beechnut]]
	[[Category: Almeida, F C.L]]		[[Category: Almeida, F C.L]]
	[[Category: Asam, A]]		[[Category: Asam, A]]

OCA at 21:46, 9 August 2018

OCA — Thu, 09 Aug 2018 21:46:16 GMT

←Older revision		Revision as of 21:46, 9 August 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6alk is ON HOLD until Paper Publication~~	+	==NMR solution structure of the major beech pollen allergen Fag s 1==
-		+	<StructureSection load='6alk' size='340' side='right' caption='[[6alk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-	~~Authors: Moraes, A.H., Asam, A., Almeida, F.C.L., Wallner, M., Ferreira, F., Valente, A.P.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6alk]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ALK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ALK FirstGlance]. <br>
-	~~Description:~~ NMR solution structure of the major beech pollen allergen Fag s 1	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6alk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6alk OCA], [http://pdbe.org/6alk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6alk RCSB], [http://www.ebi.ac.uk/pdbsum/6alk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6alk ProSAT]</span></td></tr>
-	[[~~Category: Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Valente, A~~.P]]	+	__TOC__
-	[[~~Category~~: ~~Wallner~~, M]]	+	</StructureSection>
-	[[Category: Almeida, F.C.L]]	+	[[Category: Almeida, F C.L]]
	[[Category: Asam, A]]		[[Category: Asam, A]]
-	[[Category: Moraes, A.H]]
	[[Category: Ferreira, F]]		[[Category: Ferreira, F]]
		+	[[Category: Moraes, A H]]
		+	[[Category: Valente, A P]]
		+	[[Category: Wallner, M]]
		+	[[Category: Allergen]]
		+	[[Category: Conformational diversity]]
		+	[[Category: Ligand binding]]

OCA at 05:26, 11 October 2017

OCA — Wed, 11 Oct 2017 05:26:14 GMT

←Older revision		Revision as of 05:26, 11 October 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6alk is ON HOLD	+	The entry 6alk is ON HOLD until Paper Publication

	Authors: Moraes, A.H., Asam, A., Almeida, F.C.L., Wallner, M., Ferreira, F., Valente, A.P.		Authors: Moraes, A.H., Asam, A., Almeida, F.C.L., Wallner, M., Ferreira, F., Valente, A.P.
Line 7:		Line 7:
	Description: NMR solution structure of the major beech pollen allergen Fag s 1		Description: NMR solution structure of the major beech pollen allergen Fag s 1
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Moraes, A.H]]
-	[[Category: Almeida, F.C.L]]
-	[[Category: Asam, A]]
	[[Category: Valente, A.P]]		[[Category: Valente, A.P]]
	[[Category: Wallner, M]]		[[Category: Wallner, M]]
		+	[[Category: Almeida, F.C.L]]
		+	[[Category: Asam, A]]
		+	[[Category: Moraes, A.H]]
	[[Category: Ferreira, F]]		[[Category: Ferreira, F]]

OCA: Protected "6alk" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 16:32:37 GMT

Protected "6alk" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:32, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 6alk is ON HOLD Authors: Moraes, A.H., Asam, A., Almeida, F.C.L., Wallner, M., Ferreira, F., Valente, A.P. Description: NMR solution structure of t...

OCA — Wed, 27 Sep 2017 16:32:36 GMT

New page: '''Unreleased structure''' The entry 6alk is ON HOLD Authors: Moraes, A.H., Asam, A., Almeida, F.C.L., Wallner, M., Ferreira, F., Valente, A.P. Description: NMR solution structure of t...

New page

'''Unreleased structure'''

The entry 6alk is ON HOLD

Authors: Moraes, A.H., Asam, A., Almeida, F.C.L., Wallner, M., Ferreira, F., Valente, A.P.

Description: NMR solution structure of the major beech pollen allergen Fag s 1
[[Category: Unreleased Structures]]
[[Category: Moraes, A.H]]
[[Category: Almeida, F.C.L]]
[[Category: Asam, A]]
[[Category: Valente, A.P]]
[[Category: Wallner, M]]
[[Category: Ferreira, F]]