6arf - Revision history

OCA at 14:18, 13 March 2024

OCA — Wed, 13 Mar 2024 14:18:05 GMT

←Older revision		Revision as of 14:18, 13 March 2024
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	<StructureSection load='6arf' size='340' side='right'caption='[[6arf]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='6arf' size='340' side='right'caption='[[6arf]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6arf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6ARF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6arf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_Af293 Aspergillus fumigatus Af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ARF FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.702Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[6are\|6are]], [[6aqp\|6aqp]]~~<~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9]~~ </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6arf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6arf OCA], [https://pdbe.org/6arf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6arf RCSB], [https://www.ebi.ac.uk/pdbsum/6arf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6arf ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6arf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6arf OCA], [~~http~~://pdbe.org/6arf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6arf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6arf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6arf ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ER10B_ASPFU ER10B_ASPFU] Acetyl-CoA acetyltransferase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (Ref.6). Erg10B catalyzes the formation of acetoacetyl-CoA from acetyl-CoA (Ref.6). The first module starts with the action of the cytosolic acetyl-CoA acetyltransferase erg10B that catalyzes the formation of acetoacetyl-CoA. The hydroxymethylglutaryl-CoA synthases erg13A and erg13B then condense acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductases hmg1 and hmg2. Mevalonate is also a precursor for the extracellular siderophore triacetylfusarinine C (TAFC) (PubMed:16110826, PubMed:22106303) (Probable).<ref>PMID:17352532</ref> <ref>PMID:16110826</ref> <ref>PMID:22106303</ref>
		+
		+	==See Also==
		+	*[[Thiolase 3D structures\|Thiolase 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Acetyl-CoA C-acetyltransferase~~]]	+	[[Category: Aspergillus fumigatus Af293]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bond~~, C S~~]]	+	[[Category: Bond CS]]
-	[[Category: Bruning~~, J B~~]]	+	[[Category: Bruning JB]]
-	[[Category: Marshall~~, A C]]~~	+	[[Category: Marshall AC]]
-	~~[[Category: Claisen condensation]]~~	+
-	~~[[Category: Monovalent cation binding]]~~	+
-	~~[[Category: Thiolase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 21:31, 28 October 2020

OCA — Wed, 28 Oct 2020 21:31:04 GMT

←Older revision		Revision as of 21:31, 28 October 2020
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	==Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with potassium ions==		==Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with potassium ions==
-	<StructureSection load='6arf' size='340' side='right' caption='[[6arf]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='6arf' size='340' side='right'caption='[[6arf]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6arf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARF OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ARF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6arf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ARF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6are\|6are]], [[6aqp\|6aqp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6are\|6are]], [[6aqp\|6aqp]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6arf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6arf OCA], [http://pdbe.org/6arf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6arf RCSB], [http://www.ebi.ac.uk/pdbsum/6arf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6arf ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6arf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6arf OCA], [http://pdbe.org/6arf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6arf RCSB], [http://www.ebi.ac.uk/pdbsum/6arf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6arf ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Acetyl-CoA C-acetyltransferase]]		[[Category: Acetyl-CoA C-acetyltransferase]]
		+	[[Category: Large Structures]]
	[[Category: Bond, C S]]		[[Category: Bond, C S]]
	[[Category: Bruning, J B]]		[[Category: Bruning, J B]]

OCA at 05:31, 30 May 2018

OCA — Wed, 30 May 2018 05:31:16 GMT

←Older revision		Revision as of 05:31, 30 May 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6arf is ~~ON HOLD until Paper Publication~~	+	==Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with potassium ions==
-		+	<StructureSection load='6arf' size='340' side='right' caption='[[6arf]], [[Resolution\|resolution]] 1.70Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6arf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ARF FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6are\|6are]], [[6aqp\|6aqp]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6arf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6arf OCA], [http://pdbe.org/6arf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6arf RCSB], [http://www.ebi.ac.uk/pdbsum/6arf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6arf ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Acetyl-CoA C-acetyltransferase]]
		+	[[Category: Bond, C S]]
		+	[[Category: Bruning, J B]]
		+	[[Category: Marshall, A C]]
		+	[[Category: Claisen condensation]]
		+	[[Category: Monovalent cation binding]]
		+	[[Category: Thiolase]]
		+	[[Category: Transferase]]

OCA: Protected "6arf" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 16:42:26 GMT

Protected "6arf" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:42, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 6arf is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Wed, 27 Sep 2017 16:42:24 GMT

New page: '''Unreleased structure''' The entry 6arf is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6arf is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]