6aw5 - Revision history

OCA at 14:26, 4 October 2023

OCA — Wed, 04 Oct 2023 14:26:52 GMT

←Older revision		Revision as of 14:26, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='6aw5' size='340' side='right'caption='[[6aw5]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='6aw5' size='340' side='right'caption='[[6aw5]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6aw5]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Nanga Nanga~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6AW5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6aw5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nannospalax_galili Nannospalax galili]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AW5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw5 OCA], [~~http~~://pdbe.org/6aw5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6aw5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6aw5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw5 ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw5 OCA], [https://pdbe.org/6aw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6aw5 RCSB], [https://www.ebi.ac.uk/pdbsum/6aw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw5 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A452CSQ2_NANGA A0A452CSQ2_NANGA] Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.[ARBA:ARBA00003256]

	==See Also==		==See Also==
Line 13:		Line 16:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Nanga~~]]	+	[[Category: Nannospalax galili]]
-	[[Category: Battaile~~, K P~~]]	+	[[Category: Battaile KP]]
-	[[Category: Deng, Y]]	+	[[Category: Deng Y]]
-	[[Category: Hanzlik~~, R P~~]]	+	[[Category: Hanzlik RP]]
-	[[Category: Lovell, S]]	+	[[Category: Lovell S]]
-	[[Category: Mehzabeen, N]]	+	[[Category: Mehzabeen N]]
-	[[Category: Moskovitz, J]]	+	[[Category: Moskovitz J]]
-	[[Category: Shams, I]]	+	[[Category: Shams I]]
-	~~[[Category: Comt]]~~	+
-	~~[[Category: S-adenosylmethionine binding]]~~	+
-	~~[[Category: Spalax]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 10:07, 1 January 2020

OCA — Wed, 01 Jan 2020 10:07:05 GMT

←Older revision		Revision as of 10:07, 1 January 2020
Line 1:		Line 1:

	==1.90A resolution structure of catechol O-methyltransferase (COMT) L136M (hexagonal form) from Nannospalax galili==		==1.90A resolution structure of catechol O-methyltransferase (COMT) L136M (hexagonal form) from Nannospalax galili==
-	<StructureSection load='6aw5' size='340' side='right' caption='[[6aw5]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='6aw5' size='340' side='right'caption='[[6aw5]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6aw5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nanga Nanga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AW5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[6aw5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nanga Nanga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AW5 FirstGlance]. <br>
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw5 OCA], [http://pdbe.org/6aw5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aw5 RCSB], [http://www.ebi.ac.uk/pdbsum/6aw5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw5 OCA], [http://pdbe.org/6aw5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aw5 RCSB], [http://www.ebi.ac.uk/pdbsum/6aw5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw5 ProSAT]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Catechol O-methyltransferase 3D structures\|Catechol O-methyltransferase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Nanga]]		[[Category: Nanga]]
	[[Category: Battaile, K P]]		[[Category: Battaile, K P]]

OCA at 07:44, 21 February 2019

OCA — Thu, 21 Feb 2019 07:44:29 GMT

←Older revision		Revision as of 07:44, 21 February 2019
Line 3:		Line 3:
	<StructureSection load='6aw5' size='340' side='right' caption='[[6aw5]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='6aw5' size='340' side='right' caption='[[6aw5]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6aw5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AW5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6aw5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nanga Nanga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AW5 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw5 OCA], [http://pdbe.org/6aw5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aw5 RCSB], [http://www.ebi.ac.uk/pdbsum/6aw5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw5 OCA], [http://pdbe.org/6aw5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aw5 RCSB], [http://www.ebi.ac.uk/pdbsum/6aw5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw5 ProSAT]</span></td></tr>
Line 9:		Line 9:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Nanga]]
	[[Category: Battaile, K P]]		[[Category: Battaile, K P]]
	[[Category: Deng, Y]]		[[Category: Deng, Y]]

OCA at 07:31, 12 September 2018

OCA — Wed, 12 Sep 2018 07:31:07 GMT

←Older revision		Revision as of 07:31, 12 September 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6aw5 is ~~ON HOLD until Paper Publication~~	+	==1.90A resolution structure of catechol O-methyltransferase (COMT) L136M (hexagonal form) from Nannospalax galili==
-		+	<StructureSection load='6aw5' size='340' side='right' caption='[[6aw5]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~Authors~~: ~~Lovell~~, S., ~~Mehzabeen~~, N., ~~Battaile~~, K.P., Deng, Y., Hanzlik, R.P~~., Shams, I., Moskovitz, J.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6aw5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AW5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AW5 FirstGlance]. <br>
-	~~Description~~: ~~1.90A resolution structure of catechol O-methyltransferase (COMT) L136M (hexagonal form) from Nannospalax galili~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aw5 OCA], [http://pdbe.org/6aw5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aw5 RCSB], [http://www.ebi.ac.uk/pdbsum/6aw5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aw5 ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Battaile, K P]]
		+	[[Category: Deng, Y]]
		+	[[Category: Hanzlik, R P]]
		+	[[Category: Lovell, S]]
		+	[[Category: Mehzabeen, N]]
	[[Category: Moskovitz, J]]		[[Category: Moskovitz, J]]
	[[Category: Shams, I]]		[[Category: Shams, I]]
-	[[Category: ~~Hanzlik, R.P~~]]	+	[[Category: Comt]]
-	[[Category: ~~Battaile, K.P]]~~	+	[[Category: S-adenosylmethionine binding]]
-	~~[[Category: Lovell,~~ S]]	+	[[Category: Spalax]]
-	[[Category: ~~Deng, Y~~]]	+	[[Category: Transferase]]
-	[[Category: ~~Mehzabeen, N~~]]	+

OCA: Protected "6aw5" [edit=sysop:move=sysop]

OCA — Wed, 27 Sep 2017 16:51:44 GMT

Protected "6aw5" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:51, 27 September 2017

OCA: New page: '''Unreleased structure''' The entry 6aw5 is ON HOLD until Paper Publication Authors: Lovell, S., Mehzabeen, N., Battaile, K.P., Deng, Y., Hanzlik, R.P., Shams, I., Moskovitz, J. Descr...

OCA — Wed, 27 Sep 2017 16:51:43 GMT

New page: '''Unreleased structure''' The entry 6aw5 is ON HOLD until Paper Publication Authors: Lovell, S., Mehzabeen, N., Battaile, K.P., Deng, Y., Hanzlik, R.P., Shams, I., Moskovitz, J. Descr...

New page

'''Unreleased structure'''

The entry 6aw5 is ON HOLD until Paper Publication

Authors: Lovell, S., Mehzabeen, N., Battaile, K.P., Deng, Y., Hanzlik, R.P., Shams, I., Moskovitz, J.

Description: 1.90A resolution structure of catechol O-methyltransferase (COMT) L136M (hexagonal form) from Nannospalax galili
[[Category: Unreleased Structures]]
[[Category: Moskovitz, J]]
[[Category: Shams, I]]
[[Category: Hanzlik, R.P]]
[[Category: Battaile, K.P]]
[[Category: Lovell, S]]
[[Category: Deng, Y]]
[[Category: Mehzabeen, N]]