6b6k - Revision history

OCA at 14:33, 4 October 2023

OCA — Wed, 04 Oct 2023 14:33:45 GMT

←Older revision		Revision as of 14:33, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='6b6k' size='340' side='right'caption='[[6b6k]], [[Resolution\|resolution]] 1.46Å' scene=''>		<StructureSection load='6b6k' size='340' side='right'caption='[[6b6k]], [[Resolution\|resolution]] 1.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6b6k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6K OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6B6K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6b6k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B6K FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CVG:6~~-~~methylpyridazin-3-ol'>CVG</scene>~~, ~~<scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.46Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CVG:6-methylpyridazin-3-ol'>CVG</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td><~~td class="sblockDat">[[5cxq\|5cxq]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6k OCA], [https://pdbe.org/6b6k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b6k RCSB], [https://www.ebi.ac.uk/pdbsum/6b6k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6k ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6k OCA], [~~http~~://pdbe.org/6b6k PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6b6k RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6b6k PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6k ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]	+	[https://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]

	==See Also==		==See Also==
Line 18:		Line 16:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Purine-nucleoside phosphorylase~~]]	+	[[Category: Schistosoma mansoni]]
-	[[Category: Barbosa~~, J A.R G~~]]	+	[[Category: Barbosa JARG]]
-	[[Category: Bird, L]]	+	[[Category: Bird L]]
-	[[Category: Collins, P]]	+	[[Category: Collins P]]
-	[[Category: Delft~~, F V~~]]	+	[[Category: Delft FV]]
-	[[Category: Faheem, M]]	+	[[Category: Faheem M]]
-	[[Category: Neto~~, J B~~]]	+	[[Category: Neto JB]]
-	[[Category: Pearce~~, N M~~]]	+	[[Category: Pearce NM]]
-	[[Category: Pereira~~, H M~~]]	+	[[Category: Pereira HM]]
-	[[Category: Valadares~~, N F]]~~	+	[[Category: Valadares NF]]
-	~~[[Category: Purine nucleoside phosphorylase]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transferase-inhibitor complex~~]]	+

OCA at 21:37, 28 October 2020

OCA — Wed, 28 Oct 2020 21:37:17 GMT

←Older revision		Revision as of 21:37, 28 October 2020
Line 1:		Line 1:

	==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3-one==		==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3-one==
-	<StructureSection load='6b6k' size='340' side='right' caption='[[6b6k]], [[Resolution\|resolution]] 1.46Å' scene=''>	+	<StructureSection load='6b6k' size='340' side='right'caption='[[6b6k]], [[Resolution\|resolution]] 1.46Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6b6k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6K OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6B6K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6b6k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6K OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6B6K FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CVG:6-methylpyridazin-3-ol'>CVG</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CVG:6-methylpyridazin-3-ol'>CVG</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cxq\|5cxq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cxq\|5cxq]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6k OCA], [http://pdbe.org/6b6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6k RCSB], [http://www.ebi.ac.uk/pdbsum/6b6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6k ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6k OCA], [http://pdbe.org/6b6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6k RCSB], [http://www.ebi.ac.uk/pdbsum/6b6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6k ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]		[[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]
		+
		+	==See Also==
		+	*[[Purine nucleoside phosphorylase 3D structures\|Purine nucleoside phosphorylase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Purine-nucleoside phosphorylase]]		[[Category: Purine-nucleoside phosphorylase]]
	[[Category: Barbosa, J A.R G]]		[[Category: Barbosa, J A.R G]]

OCA at 08:03, 10 October 2018

OCA — Wed, 10 Oct 2018 08:03:56 GMT

←Older revision		Revision as of 08:03, 10 October 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6b6k ~~is ON HOLD until Paper Publication~~	+	==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3-one==
-		+	<StructureSection load='6b6k' size='340' side='right' caption='[[6b6k]], [[Resolution\|resolution]] 1.46Å' scene=''>
-	~~Authors~~: ~~Faheem, M~~.~~, Neto, J~~.B.~~, Collins, P~~.~~, Pearce, N~~.M., ~~Valadares~~, N.F., ~~Bird, L~~., ~~Pereira, H~~.M., ~~Delft~~, F.V., ~~Barbosa, J~~.A.R.G.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6b6k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B6K FirstGlance]. <br>
-	~~Description~~: ~~Crystal Structure~~ of ~~Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni~~ in ~~complex with 6~~-~~methyl-2~~,3-~~dihydropyridazin~~-~~3-one~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CVG:6-methylpyridazin-3-ol'>CVG</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
-	[[Category: ~~Pearce~~, N.M]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cxq\|5cxq]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6k OCA], [http://pdbe.org/6b6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b6k RCSB], [http://www.ebi.ac.uk/pdbsum/6b6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6k ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Purine-nucleoside phosphorylase]]
		+	[[Category: Barbosa, J A.R G]]
		+	[[Category: Bird, L]]
	[[Category: Collins, P]]		[[Category: Collins, P]]
		+	[[Category: Delft, F V]]
	[[Category: Faheem, M]]		[[Category: Faheem, M]]
-	[[Category: ~~Delft~~, ~~F.V~~]]	+	[[Category: Neto, J B]]
-	[[Category: Pereira, H.M]]	+	[[Category: Pearce, N M]]
-	[[Category: ~~Neto~~, ~~J.B~~]]	+	[[Category: Pereira, H M]]
-	[[Category: ~~Barbosa, J.A.R.G~~]]	+	[[Category: Valadares, N F]]
-	[[Category: ~~Valadares, N.F~~]]	+	[[Category: Purine nucleoside phosphorylase]]
-	[[Category: ~~Bird, L~~]]	+	[[Category: Transferase]]
		+	[[Category: Transferase-inhibitor complex]]

OCA at 05:03, 14 March 2018

OCA — Wed, 14 Mar 2018 05:03:41 GMT

←Older revision		Revision as of 05:03, 14 March 2018
Line 5:		Line 5:
	Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.		Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.

-	Description: Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 3-~~methylpyridazin~~-1-~~ium~~-6-~~olate~~	+	Description: Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3-one
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Pearce, N.M]]		[[Category: Pearce, N.M]]
	[[Category: Collins, P]]		[[Category: Collins, P]]
-	[[Category: Pereira, H.M]]
-	[[Category: Barbosa, J.A.R.G]]
-	[[Category: Bird, L]]
	[[Category: Faheem, M]]		[[Category: Faheem, M]]
	[[Category: Delft, F.V]]		[[Category: Delft, F.V]]
		+	[[Category: Pereira, H.M]]
	[[Category: Neto, J.B]]		[[Category: Neto, J.B]]
		+	[[Category: Barbosa, J.A.R.G]]
	[[Category: Valadares, N.F]]		[[Category: Valadares, N.F]]
		+	[[Category: Bird, L]]

OCA at 04:55, 20 December 2017

OCA — Wed, 20 Dec 2017 04:55:16 GMT

←Older revision		Revision as of 04:55, 20 December 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6b6k is ON HOLD	+	The entry 6b6k is ON HOLD until Paper Publication

	Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.		Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.
Line 9:		Line 9:
	[[Category: Pearce, N.M]]		[[Category: Pearce, N.M]]
	[[Category: Collins, P]]		[[Category: Collins, P]]
		+	[[Category: Pereira, H.M]]
		+	[[Category: Barbosa, J.A.R.G]]
		+	[[Category: Bird, L]]
	[[Category: Faheem, M]]		[[Category: Faheem, M]]
	[[Category: Delft, F.V]]		[[Category: Delft, F.V]]
-	[[Category: Pereira, H.M]]
	[[Category: Neto, J.B]]		[[Category: Neto, J.B]]
-	[[Category: Barbosa, J.A.R.G]]
	[[Category: Valadares, N.F]]		[[Category: Valadares, N.F]]
-	[[Category: Bird, L]]

OCA: Protected "6b6k" [edit=sysop:move=sysop]

OCA — Wed, 11 Oct 2017 05:32:35 GMT

Protected "6b6k" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:32, 11 October 2017

OCA: New page: '''Unreleased structure''' The entry 6b6k is ON HOLD Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G....

OCA — Wed, 11 Oct 2017 05:32:34 GMT

New page: '''Unreleased structure''' The entry 6b6k is ON HOLD Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G....

New page

'''Unreleased structure'''

The entry 6b6k is ON HOLD

Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.

Description: Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 3-methylpyridazin-1-ium-6-olate
[[Category: Unreleased Structures]]
[[Category: Pearce, N.M]]
[[Category: Collins, P]]
[[Category: Faheem, M]]
[[Category: Delft, F.V]]
[[Category: Pereira, H.M]]
[[Category: Neto, J.B]]
[[Category: Barbosa, J.A.R.G]]
[[Category: Valadares, N.F]]
[[Category: Bird, L]]