6bka - Revision history

OCA at 14:44, 4 October 2023

OCA — Wed, 04 Oct 2023 14:44:11 GMT

←Older revision		Revision as of 14:44, 4 October 2023
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	<StructureSection load='6bka' size='340' side='right'caption='[[6bka]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='6bka' size='340' side='right'caption='[[6bka]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6bka]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_10743 Atcc 10743~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6BKA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6bka]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cyberlindnera_mrakii Cyberlindnera mrakii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BKA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=33O:3,6,9,12,15,18,21,24,27,30,33,36-DODECAOXAOCTATRIACONTANE-1,38-DIOL'>33O</scene>, <scene name='pdbligand=~~FMN~~:~~FLAVIN+MONONUCLEOTIDE~~'>~~FMN~~</scene>, <scene name='pdbligand=~~GOL~~:~~GLYCEROL~~'>~~GOL~~</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.65Å</td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~CSD~~:~~3-SULFINOALANINE~~'>~~CSD~~</scene~~></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=33O:3,6,9,12,15,18,21,24,27,30,33,36-DODECAOXAOCTATRIACONTANE-1,38-DIOL'>33O</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitronate_monooxygenase Nitronate monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.12.16 1.13.12.16] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bka OCA], [https://pdbe.org/6bka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bka RCSB], [https://www.ebi.ac.uk/pdbsum/6bka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bka ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6bka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bka OCA], [~~http~~://pdbe.org/6bka PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6bka RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6bka PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6bka ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/2NPD_CYBMR 2NPD_CYBMR]] Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites.	+	[https://www.uniprot.org/uniprot/2NPD_CYBMR 2NPD_CYBMR] Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 10743~~]]	+	[[Category: Cyberlindnera mrakii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Nitronate monooxygenase]]~~	+	[[Category: Agniswamy J]]
-	[[Category: Agniswamy, J]]	+	[[Category: Fang Y-F]]
-	[[Category: Fang, Y F]]	+	[[Category: Weber IT]]
-	[[Category: Weber~~, I T]]~~	+
-	~~[[Category: Monooxygenase]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Propionate 3-nitronate~~]]	+

OCA at 08:19, 27 November 2019

OCA — Wed, 27 Nov 2019 08:19:27 GMT

←Older revision		Revision as of 08:19, 27 November 2019
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	==Crystal Structure of Nitronate Monooxygenase from Cyberlindnera saturnus==		==Crystal Structure of Nitronate Monooxygenase from Cyberlindnera saturnus==
-	<StructureSection load='6bka' size='340' side='right' caption='[[6bka]], [[Resolution\|resolution]] 1.65Å' scene=''>	+	<StructureSection load='6bka' size='340' side='right'caption='[[6bka]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6bka]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_10743 Atcc 10743]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BKA FirstGlance]. <br>		<table><tr><td colspan='2'>[[6bka]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_10743 Atcc 10743]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BKA FirstGlance]. <br>
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 6bka" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6bka" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Monooxygenase 3D structures\|Monooxygenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Atcc 10743]]		[[Category: Atcc 10743]]
		+	[[Category: Large Structures]]
	[[Category: Nitronate monooxygenase]]		[[Category: Nitronate monooxygenase]]
	[[Category: Agniswamy, J]]		[[Category: Agniswamy, J]]

OCA at 08:30, 2 May 2018

OCA — Wed, 02 May 2018 08:30:48 GMT

←Older revision		Revision as of 08:30, 2 May 2018
Line 3:		Line 3:
	<StructureSection load='6bka' size='340' side='right' caption='[[6bka]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='6bka' size='340' side='right' caption='[[6bka]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6bka]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BKA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6bka]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_10743 Atcc 10743]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BKA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=33O:3,6,9,12,15,18,21,24,27,30,33,36-DODECAOXAOCTATRIACONTANE-1,38-DIOL'>33O</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=33O:3,6,9,12,15,18,21,24,27,30,33,36-DODECAOXAOCTATRIACONTANE-1,38-DIOL'>33O</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 10743]]
	[[Category: Nitronate monooxygenase]]		[[Category: Nitronate monooxygenase]]
	[[Category: Agniswamy, J]]		[[Category: Agniswamy, J]]

OCA at 06:33, 15 February 2018

OCA — Thu, 15 Feb 2018 06:33:28 GMT

←Older revision		Revision as of 06:33, 15 February 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6bka is ~~ON HOLD until Paper~~ Publication	+	==Crystal Structure of Nitronate Monooxygenase from Cyberlindnera saturnus==
		+	<StructureSection load='6bka' size='340' side='right' caption='[[6bka]], [[Resolution\|resolution]] 1.65Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6bka]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BKA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=33O:3,6,9,12,15,18,21,24,27,30,33,36-DODECAOXAOCTATRIACONTANE-1,38-DIOL'>33O</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitronate_monooxygenase Nitronate monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.12.16 1.13.12.16] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bka OCA], [http://pdbe.org/6bka PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bka RCSB], [http://www.ebi.ac.uk/pdbsum/6bka PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bka ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/2NPD_CYBMR 2NPD_CYBMR]] Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Nitronate monooxygenase (NMO) is an FMN-dependent enzyme that oxidizes the neurotoxin propionate 3-nitronate (P3N) and represents the best-known system for P3N detoxification in different organisms. The crystal structure of the first eukaryotic Class I NMO from Cyberlindnera saturnus (CsNMO) has been solved at 1.65 A resolution and refined to an R-factor of 14.0%. The three-dimensional structures of yeast CsNMO and bacterial PaNMO are highly conserved with the exception of three additional loops on the surface in the CsNMO enzyme and differences in four active sites residues. A PEG molecule was identified in the structure and formed extensive interactions with CsNMO, suggesting a specific binding site; however, 8% PEG showed no significant effect on the enzyme activity. This new crystal structure of a eukaryotic NMO provides insight into the function of this class of enzymes.

-	~~Authors: Agniswamy~~, J., ~~Fang~~, ~~Y.-F.~~, ~~Weber~~, I.T.	+	Crystal structure of yeast nitronate monooxygenase from Cyberlindnera saturnus.,Agniswamy J, Reis RAG, Wang YF, Smitherman C, Su D, Weber I, Gadda G Proteins. 2018 Jan 31. doi: 10.1002/prot.25470. PMID:29383742<ref>PMID:29383742</ref>

-	~~Description: Crystal Structure~~ of ~~Nitronate Monooxygenase from Cyberlindnera saturnus~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 6bka" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Nitronate monooxygenase]]
	[[Category: Agniswamy, J]]		[[Category: Agniswamy, J]]
-	[[Category: Fang, Y.-F]]	+	[[Category: Fang, Y F]]
-	[[Category: Weber, I.T]]	+	[[Category: Weber, I T]]
		+	[[Category: Monooxygenase]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Propionate 3-nitronate]]

OCA at 06:33, 22 November 2017

OCA — Wed, 22 Nov 2017 06:33:56 GMT

←Older revision		Revision as of 06:33, 22 November 2017
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6bka is ON HOLD	+	The entry 6bka is ON HOLD until Paper Publication

	Authors: Agniswamy, J., Fang, Y.-F., Weber, I.T.		Authors: Agniswamy, J., Fang, Y.-F., Weber, I.T.

OCA: Protected "6bka" [edit=sysop:move=sysop]

OCA — Wed, 15 Nov 2017 06:24:37 GMT

Protected "6bka" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:24, 15 November 2017

OCA: New page: '''Unreleased structure''' The entry 6bka is ON HOLD Authors: Agniswamy, J., Fang, Y.-F., Weber, I.T. Description: Crystal Structure of Nitronate Monooxygenase from Cyberlindnera satur...

OCA — Wed, 15 Nov 2017 06:24:36 GMT

New page: '''Unreleased structure''' The entry 6bka is ON HOLD Authors: Agniswamy, J., Fang, Y.-F., Weber, I.T. Description: Crystal Structure of Nitronate Monooxygenase from Cyberlindnera satur...

New page

'''Unreleased structure'''

The entry 6bka is ON HOLD

Authors: Agniswamy, J., Fang, Y.-F., Weber, I.T.

Description: Crystal Structure of Nitronate Monooxygenase from Cyberlindnera saturnus
[[Category: Unreleased Structures]]
[[Category: Agniswamy, J]]
[[Category: Fang, Y.-F]]
[[Category: Weber, I.T]]