6bwx - Revision history

OCA at 14:24, 13 March 2024

OCA — Wed, 13 Mar 2024 14:24:46 GMT

←Older revision		Revision as of 14:24, 13 March 2024
Line 3:		Line 3:
	<SX load='6bwx' size='340' side='right' viewer='molstar' caption='[[6bwx]], [[Resolution\|resolution]] 2.84Å' scene=''>		<SX load='6bwx' size='340' side='right' viewer='molstar' caption='[[6bwx]], [[Resolution\|resolution]] 2.84Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6bwx]] is a 60 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6BWX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6bwx]] is a 60 chain structure with sequence from [https://en.wikipedia.org/wiki/Bufavirus-1 Bufavirus-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BWX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6bwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwx OCA], [~~http~~://pdbe.org/6bwx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6bwx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6bwx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwx ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.84Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwx OCA], [https://pdbe.org/6bwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bwx RCSB], [https://www.ebi.ac.uk/pdbsum/6bwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwx ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/A0A097PIK3_9VIRU A0A097PIK3_9VIRU]
-	Bufavirus strain 1 (BuV1), a member of the Protoparvovirus genus of the Parvoviridae, was first isolated from fecal samples of children with acute diarrhea in Burkina Faso. Since this initial discovery, BuVs have been isolated in several countries, including Finland, the Netherlands, and Bhutan, in pediatric patients exhibiting similar symptoms. Towards their characterization, the structures of virus-like particles of BuV1, BuV2, and BuV3, the current known genotypes, have been determined by cryo-electron microscopy and image reconstruction to 2.84, 3.79, and 3.25 A, respectively. The BuVs, 65-73% identical in amino acid sequence, conserve the major viral protein, VP2, structure and general capsid surface features of parvoviruses. These include a core beta-barrel (betaB-betaI), alpha-helix A, and large surface loops inserted between these elements in VP2. The capsid contains depressions at the icosahedral 2-fold and around the 5-fold axes, and has three separated protrusions surrounding the 3-fold axes. Structure comparison among the BuVs and to available parvovirus structures revealed capsid surface variations and capsid 3-fold protrusions that depart from the single pinwheel arrangement of the animal protoparvoviruses. These structures provide a platform to begin the molecular characterization of these potentially pathogenic viruses.	+
-		+
-	Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy.,Ilyas M, Mietzsch M, Kailasan S, Vaisanen E, Luo M, Chipman P, Smith JK, Kurian J, Sousa D, McKenna R, Soderlund-Venermo M, Agbandje-McKenna M Viruses. 2018 Jan 4;10(1). pii: ~~v10010022. doi: 10.3390~~/~~v10010022. PMID:29300333<ref>PMID:29300333<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 6bwx" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</SX>		</SX>
		+	[[Category: Bufavirus-1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Agbandje-McKenna, M]]	+	[[Category: Agbandje-McKenna M]]
-	[[Category: Mietzsch, M]]	+	[[Category: Mietzsch M]]
-	~~[[Category: Parvovirus]]~~	+
-	~~[[Category: Protoparvovirus]]~~	+
-	~~[[Category: Virus like particle~~]]	+

OCA at 23:30, 10 April 2020

OCA — Fri, 10 Apr 2020 23:30:40 GMT

←Older revision		Revision as of 23:30, 10 April 2020
Line 3:		Line 3:
	<SX load='6bwx' size='340' side='right' viewer='molstar' caption='[[6bwx]], [[Resolution\|resolution]] 2.84Å' scene=''>		<SX load='6bwx' size='340' side='right' viewer='molstar' caption='[[6bwx]], [[Resolution\|resolution]] 2.84Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6bwx]] is a 60 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWX OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6BWX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6bwx]] is a 60 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6BWX FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6bwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwx OCA], [http://pdbe.org/6bwx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bwx RCSB], [http://www.ebi.ac.uk/pdbsum/6bwx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwx ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6bwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwx OCA], [http://pdbe.org/6bwx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bwx RCSB], [http://www.ebi.ac.uk/pdbsum/6bwx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 20:35, 6 March 2020

OCA — Fri, 06 Mar 2020 20:35:22 GMT

←Older revision		Revision as of 20:35, 6 March 2020
Line 1:		Line 1:
-	~~{{Large structure}}~~	+
	==Atomic resolution structure of human bufavirus 1==		==Atomic resolution structure of human bufavirus 1==
-	<~~StructureSection~~ load='6bwx' size='340' side='right' caption='[[6bwx]], [[Resolution\|resolution]] 2.84Å' scene=''>	+	<SX load='6bwx' size='340' side='right' viewer='molstar' caption='[[6bwx]], [[Resolution\|resolution]] 2.84Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6bwx]] is a 60 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BWX FirstGlance]. <br>		<table><tr><td colspan='2'>[[6bwx]] is a 60 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BWX FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwx OCA], [http://pdbe.org/6bwx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bwx RCSB], [http://www.ebi.ac.uk/pdbsum/6bwx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwx ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwx OCA], [http://pdbe.org/6bwx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bwx RCSB], [http://www.ebi.ac.uk/pdbsum/6bwx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwx ProSAT]</span></td></tr>
	</table>		</table>
-	{{Large structure}}
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 18:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
		+	[[Category: Large Structures]]
	[[Category: Agbandje-McKenna, M]]		[[Category: Agbandje-McKenna, M]]
	[[Category: Mietzsch, M]]		[[Category: Mietzsch, M]]

OCA at 18:33, 24 January 2018

OCA — Wed, 24 Jan 2018 18:33:01 GMT

←Older revision		Revision as of 18:33, 24 January 2018
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	{{Large structure}}
		+	==Atomic resolution structure of human bufavirus 1==
		+	<StructureSection load='6bwx' size='340' side='right' caption='[[6bwx]], [[Resolution\|resolution]] 2.84Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6bwx]] is a 60 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BWX FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwx OCA], [http://pdbe.org/6bwx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bwx RCSB], [http://www.ebi.ac.uk/pdbsum/6bwx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwx ProSAT]</span></td></tr>
		+	</table>
		+	{{Large structure}}
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bufavirus strain 1 (BuV1), a member of the Protoparvovirus genus of the Parvoviridae, was first isolated from fecal samples of children with acute diarrhea in Burkina Faso. Since this initial discovery, BuVs have been isolated in several countries, including Finland, the Netherlands, and Bhutan, in pediatric patients exhibiting similar symptoms. Towards their characterization, the structures of virus-like particles of BuV1, BuV2, and BuV3, the current known genotypes, have been determined by cryo-electron microscopy and image reconstruction to 2.84, 3.79, and 3.25 A, respectively. The BuVs, 65-73% identical in amino acid sequence, conserve the major viral protein, VP2, structure and general capsid surface features of parvoviruses. These include a core beta-barrel (betaB-betaI), alpha-helix A, and large surface loops inserted between these elements in VP2. The capsid contains depressions at the icosahedral 2-fold and around the 5-fold axes, and has three separated protrusions surrounding the 3-fold axes. Structure comparison among the BuVs and to available parvovirus structures revealed capsid surface variations and capsid 3-fold protrusions that depart from the single pinwheel arrangement of the animal protoparvoviruses. These structures provide a platform to begin the molecular characterization of these potentially pathogenic viruses.

-	~~The entry 6bwx is ON HOLD~~	+	Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy.,Ilyas M, Mietzsch M, Kailasan S, Vaisanen E, Luo M, Chipman P, Smith JK, Kurian J, Sousa D, McKenna R, Soderlund-Venermo M, Agbandje-McKenna M Viruses. 2018 Jan 4;10(1). pii: v10010022. doi: 10.3390/v10010022. PMID:29300333<ref>PMID:29300333</ref>

-	~~Authors: Mietzsch~~, M.~~, Agbandje-McKenna, M~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Atomic resolution structure of human bufavirus 1~~	+	<div class="pdbe-citations 6bwx" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Unreleased Structures~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Agbandje-McKenna, M]]
	[[Category: Mietzsch, M]]		[[Category: Mietzsch, M]]
-	[[Category: ~~Agbandje-Mckenna, M~~]]	+	[[Category: Parvovirus]]
		+	[[Category: Protoparvovirus]]
		+	[[Category: Virus like particle]]

OCA: Protected "6bwx" [edit=sysop:move=sysop]

OCA — Wed, 27 Dec 2017 07:19:46 GMT

Protected "6bwx" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:19, 27 December 2017

OCA: New page: '''Unreleased structure''' The entry 6bwx is ON HOLD Authors: Mietzsch, M., Agbandje-McKenna, M. Description: Atomic resolution structure of human bufavirus 1 [[Category: Unreleased St...

OCA — Wed, 27 Dec 2017 07:19:45 GMT

New page: '''Unreleased structure''' The entry 6bwx is ON HOLD Authors: Mietzsch, M., Agbandje-McKenna, M. Description: Atomic resolution structure of human bufavirus 1 [[Category: Unreleased St...

New page

'''Unreleased structure'''

The entry 6bwx is ON HOLD

Authors: Mietzsch, M., Agbandje-McKenna, M.

Description: Atomic resolution structure of human bufavirus 1
[[Category: Unreleased Structures]]
[[Category: Mietzsch, M]]
[[Category: Agbandje-Mckenna, M]]