6bzp - Revision history

OCA at 14:25, 13 March 2024

OCA — Wed, 13 Mar 2024 14:25:27 GMT

←Older revision		Revision as of 14:25, 13 March 2024
Line 3:		Line 3:
	<StructureSection load='6bzp' size='340' side='right'caption='[[6bzp]], [[Resolution\|resolution]] 1.10Å' scene=''>		<StructureSection load='6bzp' size='340' side='right'caption='[[6bzp]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6bzp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BZP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6bzp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BZP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution\|Resolution]] 1.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bzp OCA], [https://pdbe.org/6bzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bzp RCSB], [https://www.ebi.ac.uk/pdbsum/6bzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bzp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bzp OCA], [https://pdbe.org/6bzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bzp RCSB], [https://www.ebi.ac.uk/pdbsum/6bzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bzp ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[https://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN]] Frontotemporal dementia with motor neuron disease;Hereditary essential tremor;Amyotrophic lateral sclerosis;Juvenile amyotrophic lateral sclerosis;Myxofibrosarcoma;Myxoid/round cell liposarcoma. A chromosomal aberration involving FUS is found in a patient with malignant myxoid liposarcoma. Translocation t(12;16)(q13;p11) with DDIT3. A chromosomal aberration involving FUS is a cause of acute myeloid leukemia (AML). Translocation t(16;21)(p11;q22) with ERG. The disease may be caused by mutations affecting the gene represented in this entry. A chromosomal aberration involving FUS is found in a patient with angiomatoid fibrous histiocytoma. Translocation t(12;16)(q13;p11.2) with ATF1 generates a chimeric FUS/ATF1 protein. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.	+	[https://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN] Frontotemporal dementia with motor neuron disease;Hereditary essential tremor;Amyotrophic lateral sclerosis;Juvenile amyotrophic lateral sclerosis;Myxofibrosarcoma;Myxoid/round cell liposarcoma. A chromosomal aberration involving FUS is found in a patient with malignant myxoid liposarcoma. Translocation t(12;16)(q13;p11) with DDIT3. A chromosomal aberration involving FUS is a cause of acute myeloid leukemia (AML). Translocation t(16;21)(p11;q22) with ERG. The disease may be caused by mutations affecting the gene represented in this entry. A chromosomal aberration involving FUS is found in a patient with angiomatoid fibrous histiocytoma. Translocation t(12;16)(q13;p11.2) with ATF1 generates a chimeric FUS/ATF1 protein. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN]] Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.	+	[https://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN] Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Subcellular membraneless assemblies are a reinvigorated area of study in biology, with spirited scientific discussions on the forces between the low-complexity protein domains within these assemblies. To illuminate these forces, we determined the atomic structures of five segments from protein low-complexity domains associated with membraneless assemblies. Their common structural feature is the stacking of segments into kinked beta sheets that pair into protofilaments. Unlike steric zippers of amyloid fibrils, the kinked sheets interact weakly through polar atoms and aromatic side chains. By computationally threading the human proteome on our kinked structures, we identified hundreds of low-complexity segments potentially capable of forming such interactions. These segments are found in proteins as diverse as RNA binders, nuclear pore proteins, and keratins, which are known to form networks and localize to membraneless assemblies.	+
-		+
-	Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.,Hughes MP, Sawaya MR, Boyer DR, Goldschmidt L, Rodriguez JA, Cascio D, Chong L, Gonen T, Eisenberg DS Science. 2018 Feb 9;359(6376):698-701. doi: 10.1126/science.aan6398. PMID:29439243<ref>PMID:29439243</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 6bzp" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cascio, D]]	+	[[Category: Cascio D]]
-	[[Category: Eisenberg~~, D S~~]]	+	[[Category: Eisenberg DS]]
-	[[Category: Gonen, T]]	+	[[Category: Gonen T]]
-	[[Category: Hughes~~, M P~~]]	+	[[Category: Hughes MP]]
-	[[Category: Rodriguez~~, J A~~]]	+	[[Category: Rodriguez JA]]
-	[[Category: Sawaya~~, M R]]~~	+	[[Category: Sawaya MR]]
-	~~[[Category: Amyloid]]~~	+
-	~~[[Category: Lark]]~~	+
-	~~[[Category: Low-complexity]]~~	+
-	~~[[Category: Protein fibril]]~~	+
-	~~[[Category: Reversible-amyloid~~]]	+

OCA at 03:40, 2 July 2021

OCA — Fri, 02 Jul 2021 03:40:29 GMT

←Older revision		Revision as of 03:40, 2 July 2021
Line 3:		Line 3:
	<StructureSection load='6bzp' size='340' side='right'caption='[[6bzp]], [[Resolution\|resolution]] 1.10Å' scene=''>		<StructureSection load='6bzp' size='340' side='right'caption='[[6bzp]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6bzp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BZP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6BZP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6bzp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BZP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6bzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bzp OCA], [~~http~~://pdbe.org/6bzp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6bzp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6bzp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6bzp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bzp OCA], [https://pdbe.org/6bzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bzp RCSB], [https://www.ebi.ac.uk/pdbsum/6bzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bzp ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[~~http~~://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN]] Frontotemporal dementia with motor neuron disease;Hereditary essential tremor;Amyotrophic lateral sclerosis;Juvenile amyotrophic lateral sclerosis;Myxofibrosarcoma;Myxoid/round cell liposarcoma. A chromosomal aberration involving FUS is found in a patient with malignant myxoid liposarcoma. Translocation t(12;16)(q13;p11) with DDIT3. A chromosomal aberration involving FUS is a cause of acute myeloid leukemia (AML). Translocation t(16;21)(p11;q22) with ERG. The disease may be caused by mutations affecting the gene represented in this entry. A chromosomal aberration involving FUS is found in a patient with angiomatoid fibrous histiocytoma. Translocation t(12;16)(q13;p11.2) with ATF1 generates a chimeric FUS/ATF1 protein. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.	+	[[https://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN]] Frontotemporal dementia with motor neuron disease;Hereditary essential tremor;Amyotrophic lateral sclerosis;Juvenile amyotrophic lateral sclerosis;Myxofibrosarcoma;Myxoid/round cell liposarcoma. A chromosomal aberration involving FUS is found in a patient with malignant myxoid liposarcoma. Translocation t(12;16)(q13;p11) with DDIT3. A chromosomal aberration involving FUS is a cause of acute myeloid leukemia (AML). Translocation t(16;21)(p11;q22) with ERG. The disease may be caused by mutations affecting the gene represented in this entry. A chromosomal aberration involving FUS is found in a patient with angiomatoid fibrous histiocytoma. Translocation t(12;16)(q13;p11.2) with ATF1 generates a chimeric FUS/ATF1 protein. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN]] Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.	+	[[https://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN]] Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:43, 6 November 2019

OCA — Wed, 06 Nov 2019 07:43:08 GMT

←Older revision		Revision as of 07:43, 6 November 2019
Line 1:		Line 1:

	==STGGYG from low-complexity domain of FUS, residues 77-82==		==STGGYG from low-complexity domain of FUS, residues 77-82==
-	<StructureSection load='6bzp' size='340' side='right' caption='[[6bzp]], [[Resolution\|resolution]] 1.10Å' scene=''>	+	<StructureSection load='6bzp' size='340' side='right'caption='[[6bzp]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6bzp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BZP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BZP FirstGlance]. <br>		<table><tr><td colspan='2'>[[6bzp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BZP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BZP FirstGlance]. <br>
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Cascio, D]]		[[Category: Cascio, D]]
	[[Category: Eisenberg, D S]]		[[Category: Eisenberg, D S]]

OCA at 05:58, 4 April 2018

OCA — Wed, 04 Apr 2018 05:58:19 GMT

←Older revision		Revision as of 05:58, 4 April 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	The entry ~~6bzp~~ is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==STGGYG from low-complexity domain of FUS, residues 77-82==
		+	<StructureSection load='6bzp' size='340' side='right' caption='[[6bzp]], [[Resolution\|resolution]] 1.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6bzp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BZP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BZP FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TOE:2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL'>TOE</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bzp OCA], [http://pdbe.org/6bzp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bzp RCSB], [http://www.ebi.ac.uk/pdbsum/6bzp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bzp ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN]] Frontotemporal dementia with motor neuron disease;Hereditary essential tremor;Amyotrophic lateral sclerosis;Juvenile amyotrophic lateral sclerosis;Myxofibrosarcoma;Myxoid/round cell liposarcoma. A chromosomal aberration involving FUS is found in a patient with malignant myxoid liposarcoma. Translocation t(12;16)(q13;p11) with DDIT3. A chromosomal aberration involving FUS is a cause of acute myeloid leukemia (AML). Translocation t(16;21)(p11;q22) with ERG. The disease may be caused by mutations affecting the gene represented in this entry. A chromosomal aberration involving FUS is found in a patient with angiomatoid fibrous histiocytoma. Translocation t(12;16)(q13;p11.2) with ATF1 generates a chimeric FUS/ATF1 protein. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FUS_HUMAN FUS_HUMAN]] Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Subcellular membraneless assemblies are a reinvigorated area of study in biology, with spirited scientific discussions on the forces between the low-complexity protein domains within these assemblies. To illuminate these forces, we determined the atomic structures of five segments from protein low-complexity domains associated with membraneless assemblies. Their common structural feature is the stacking of segments into kinked beta sheets that pair into protofilaments. Unlike steric zippers of amyloid fibrils, the kinked sheets interact weakly through polar atoms and aromatic side chains. By computationally threading the human proteome on our kinked structures, we identified hundreds of low-complexity segments potentially capable of forming such interactions. These segments are found in proteins as diverse as RNA binders, nuclear pore proteins, and keratins, which are known to form networks and localize to membraneless assemblies.

-	~~Authors:~~ Hughes, ~~M.P.~~, ~~Rodriguez~~, ~~J.A.~~, ~~Sawaya, M.R.~~, Cascio, D., Gonen, T., Eisenberg~~, D~~.S.	+	Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.,Hughes MP, Sawaya MR, Boyer DR, Goldschmidt L, Rodriguez JA, Cascio D, Chong L, Gonen T, Eisenberg DS Science. 2018 Feb 9;359(6376):698-701. doi: 10.1126/science.aan6398. PMID:29439243<ref>PMID:29439243</ref>

-	~~Description: STGGYG from low-complexity domain~~ of ~~FUS, residues 77-82~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Gonen, T]]~~	+	<div class="pdbe-citations 6bzp" style="background-color:#fffaf0;"></div>
-	~~[[Category: Rodriguez, J.A]]~~	+	== References ==
-	~~[[Category: Eisenberg, D.S]]~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Cascio, D]]		[[Category: Cascio, D]]
-	[[Category: ~~Sawaya~~, ~~M.R~~]]	+	[[Category: Eisenberg, D S]]
-	[[Category: Hughes, M.P]]	+	[[Category: Gonen, T]]
		+	[[Category: Hughes, M P]]
		+	[[Category: Rodriguez, J A]]
		+	[[Category: Sawaya, M R]]
		+	[[Category: Amyloid]]
		+	[[Category: Lark]]
		+	[[Category: Low-complexity]]
		+	[[Category: Protein fibril]]
		+	[[Category: Reversible-amyloid]]

OCA at 05:16, 15 February 2018

OCA — Thu, 15 Feb 2018 05:16:09 GMT

←Older revision		Revision as of 05:16, 15 February 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6bzp is ON HOLD	+	The entry 6bzp is ON HOLD until Paper Publication

	Authors: Hughes, M.P., Rodriguez, J.A., Sawaya, M.R., Cascio, D., Gonen, T., Eisenberg, D.S.		Authors: Hughes, M.P., Rodriguez, J.A., Sawaya, M.R., Cascio, D., Gonen, T., Eisenberg, D.S.
Line 7:		Line 7:
	Description: STGGYG from low-complexity domain of FUS, residues 77-82		Description: STGGYG from low-complexity domain of FUS, residues 77-82
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Cascio, D]]
-	[[Category: Sawaya, M.R]]
	[[Category: Gonen, T]]		[[Category: Gonen, T]]
	[[Category: Rodriguez, J.A]]		[[Category: Rodriguez, J.A]]
	[[Category: Eisenberg, D.S]]		[[Category: Eisenberg, D.S]]
		+	[[Category: Cascio, D]]
		+	[[Category: Sawaya, M.R]]
	[[Category: Hughes, M.P]]		[[Category: Hughes, M.P]]

OCA: Protected "6bzp" [edit=sysop:move=sysop]

OCA — Wed, 03 Jan 2018 04:55:44 GMT

Protected "6bzp" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:55, 3 January 2018

OCA: New page: '''Unreleased structure''' The entry 6bzp is ON HOLD Authors: Hughes, M.P., Rodriguez, J.A., Sawaya, M.R., Cascio, D., Gonen, T., Eisenberg, D.S. Description: STGGYG from low-complexit...

OCA — Wed, 03 Jan 2018 04:55:42 GMT

New page: '''Unreleased structure''' The entry 6bzp is ON HOLD Authors: Hughes, M.P., Rodriguez, J.A., Sawaya, M.R., Cascio, D., Gonen, T., Eisenberg, D.S. Description: STGGYG from low-complexit...

New page

'''Unreleased structure'''

The entry 6bzp is ON HOLD

Authors: Hughes, M.P., Rodriguez, J.A., Sawaya, M.R., Cascio, D., Gonen, T., Eisenberg, D.S.

Description: STGGYG from low-complexity domain of FUS, residues 77-82
[[Category: Unreleased Structures]]
[[Category: Cascio, D]]
[[Category: Sawaya, M.R]]
[[Category: Gonen, T]]
[[Category: Rodriguez, J.A]]
[[Category: Eisenberg, D.S]]
[[Category: Hughes, M.P]]