6c76 - Revision history

OCA at 14:57, 4 October 2023

OCA — Wed, 04 Oct 2023 14:57:41 GMT

←Older revision		Revision as of 14:57, 4 October 2023
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	<StructureSection load='6c76' size='340' side='right'caption='[[6c76]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='6c76' size='340' side='right'caption='[[6c76]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6c76]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_baa-394 Atcc baa-394~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C76 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6C76 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6c76]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_thioreducens Thermococcus thioreducens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C76 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6c75\|6c75]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AMR53_06445, SAMN05216170_0411 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=277988 ATCC BAA-394])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c76 OCA], [https://pdbe.org/6c76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c76 RCSB], [https://www.ebi.ac.uk/pdbsum/6c76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c76 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6c76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c76 OCA], [~~http~~://pdbe.org/6c76 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6c76 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6c76 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6c76 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0Q2QQL1_9EURY A0A0Q2QQL1_9EURY]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc baa-394]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Larson, S B~~]]	+	[[Category: Thermococcus thioreducens]]
-	[[Category: ~~McPherson, A~~]]	+	[[Category: Larson SB]]
-	[[Category: ~~Alcohol dehydrogenase]]~~	+	[[Category: McPherson A]]
-	~~[[Category: Iron-containing]]~~	+
-	~~[[Category: Ogl-20p]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 06:39, 17 April 2019

OCA — Wed, 17 Apr 2019 06:39:37 GMT

←Older revision		Revision as of 06:39, 17 April 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6c76 is ~~ON HOLD until Paper~~ Publication	+	==Structure of Iron containing alcohol dehydrogenase from Thermococcus thioreducens in an orthorhombic crystal form==
		+	<StructureSection load='6c76' size='340' side='right'caption='[[6c76]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6c76]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_baa-394 Atcc baa-394]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C76 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6c75\|6c75]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AMR53_06445, SAMN05216170_0411 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=277988 ATCC BAA-394])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c76 OCA], [http://pdbe.org/6c76 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c76 RCSB], [http://www.ebi.ac.uk/pdbsum/6c76 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c76 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	An iron-containing alcohol dehydrogenase (FeADH) from the hyperthermophilic archaeon Thermococcus thioreducens was crystallized in unit cells belonging to space groups P21, P212121 and P43212, and the crystal structures were solved at 2.4, 2.1 and 1.9 A resolution, respectively, by molecular replacement using the FeADH from Thermotoga maritima (Schwarzenbacher et al., 2004) as a model. In the monoclinic and orthorhombic crystals the dehydrogenase (molecular mass 41.5 kDa) existed as a dimer containing a twofold noncrystallographic symmetry axis, which was crystallographic in the tetragonal crystals. In the monoclinic and orthorhombic asymmetric units one molecule contained iron and an NADP molecule, while the other did not. The tetragonal crystals lacked both iron and NADP. The structure is very similar to that of the FeADH from T. maritima (average r.m.s. difference for C(alpha) atoms of 1.8 A for 341 aligned atoms). The iron, which is internally sequestered, is bound entirely by amino acids from one domain: three histidines and one aspartic acid. The coenzyme is in an extended conformation, a feature that is common to the large superfamily of NADH-dependent dehydrogenases that share a classical nucleotide-binding domain. A long broad tunnel passes entirely through the enzyme between the two domains, completely encapsulating the coenzyme.

-	~~Authors~~:	+	The structure of an iron-containing alcohol dehydrogenase from a hyperthermophilic archaeon in two chemical states.,Larson SB, Jones JA, McPherson A Acta Crystallogr F Struct Biol Commun. 2019 Apr 1;75(Pt 4):217-226. doi:, 10.1107/S2053230X19001201. Epub 2019 Mar 13. PMID:30950821<ref>PMID:30950821</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6c76" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Alcohol dehydrogenase 3D structures\|Alcohol dehydrogenase 3D structures]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Atcc baa-394]]
		+	[[Category: Large Structures]]
		+	[[Category: Larson, S B]]
		+	[[Category: McPherson, A]]
		+	[[Category: Alcohol dehydrogenase]]
		+	[[Category: Iron-containing]]
		+	[[Category: Ogl-20p]]
		+	[[Category: Oxidoreductase]]

OCA at 04:59, 28 February 2018

OCA — Wed, 28 Feb 2018 04:59:27 GMT

←Older revision		Revision as of 04:59, 28 February 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6c76 is ON HOLD	+	The entry 6c76 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6c76" [edit=sysop:move=sysop]

OCA — Wed, 31 Jan 2018 04:48:33 GMT

Protected "6c76" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:48, 31 January 2018

OCA: New page: '''Unreleased structure''' The entry 6c76 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 31 Jan 2018 04:48:32 GMT

New page: '''Unreleased structure''' The entry 6c76 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6c76 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]