6ciu - Revision history

OCA at 15:05, 4 October 2023

OCA — Wed, 04 Oct 2023 15:05:47 GMT

←Older revision		Revision as of 15:05, 4 October 2023
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	<StructureSection load='6ciu' size='340' side='right'caption='[[6ciu]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='6ciu' size='340' side='right'caption='[[6ciu]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ciu]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Coral Coral~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CIU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6CIU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ciu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Galaxea_fascicularis Galaxea fascicularis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CIU FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non~~-~~Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRQ:[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC+ACID'>CRQ</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ciu OCA], [~~http~~://pdbe.org/6ciu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ciu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ciu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ciu ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CRQ:[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC+ACID'>CRQ</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ciu OCA], [https://pdbe.org/6ciu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ciu RCSB], [https://www.ebi.ac.uk/pdbsum/6ciu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ciu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q60I25_GALFS Q60I25_GALFS]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Coral~~]]	+	[[Category: Galaxea fascicularis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Knecht~~, K M~~]]	+	[[Category: Knecht KM]]
-	[[Category: Lim~~, C S~~]]	+	[[Category: Lim CS]]
-	[[Category: Oi, C]]	+	[[Category: Oi C]]
-	[[Category: Regan, L]]	+	[[Category: Regan L]]
-	[[Category: Xiong, Y]]	+	[[Category: Xiong Y]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Fluorescent protein]]~~	+
-	~~[[Category: Threonine]]~~	+
-	~~[[Category: Threonine-rich interface~~]]	+

OCA at 09:58, 4 December 2019

OCA — Wed, 04 Dec 2019 09:58:48 GMT

←Older revision

Revision as of 09:58, 4 December 2019

OCA at 08:43, 3 October 2018

OCA — Wed, 03 Oct 2018 08:43:12 GMT

←Older revision		Revision as of 08:43, 3 October 2018
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	<StructureSection load='6ciu' size='340' side='right' caption='[[6ciu]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='6ciu' size='340' side='right' caption='[[6ciu]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6ciu]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CIU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6ciu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Coral Coral]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CIU FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRQ:[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC+ACID'>CRQ</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRQ:[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC+ACID'>CRQ</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ciu OCA], [http://pdbe.org/6ciu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ciu RCSB], [http://www.ebi.ac.uk/pdbsum/6ciu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ciu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ciu OCA], [http://pdbe.org/6ciu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ciu RCSB], [http://www.ebi.ac.uk/pdbsum/6ciu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ciu ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Coral]]
	[[Category: Knecht, K M]]		[[Category: Knecht, K M]]
	[[Category: Lim, C S]]		[[Category: Lim, C S]]

OCA at 08:02, 26 September 2018

OCA — Wed, 26 Sep 2018 08:02:15 GMT

←Older revision		Revision as of 08:02, 26 September 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6ciu is ~~ON HOLD until Paper~~ Publication	+	==Structure of a Thr-rich interface in an Azami Green tetramer==
		+	<StructureSection load='6ciu' size='340' side='right' caption='[[6ciu]], [[Resolution\|resolution]] 1.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6ciu]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CIU FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRQ:[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC+ACID'>CRQ</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ciu OCA], [http://pdbe.org/6ciu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ciu RCSB], [http://www.ebi.ac.uk/pdbsum/6ciu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ciu ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We present the structure of an engineered protein-protein interface between two beta barrel proteins, which is mediated by interactions between threonine (Thr) residues. This Thr zipper structure suggests that the protein interface is stabilized by close-packing of the Thr residues, with only one inter-monomer hydrogen bond (H-bond) between two of the Thr residues. This Thr-rich interface provides a unique opportunity to study the behavior of Thr in the context of many other Thr residues. In previous work, we have shown that the side chain (chi1 ) dihedral angles of interface and core Thr residues can be predicted with high accuracy using a hard sphere plus stereochemical constraint (HS) model. Here, we demonstrate that in the Thr-rich local environment of the Thr zipper structure, we are able to predict the chi1 dihedral angles of most of the Thr residues. Some, however, are not well predicted by the HS model. We therefore employed explicitly solvated molecular dynamics (MD) simulations to further investigate the side chain conformations of these residues. The MD simulations illustrate the role that transient H-bonding to water, in combination with steric constraints, play in determining the behavior of these Thr side chains. This article is protected by copyright. All rights reserved.

-	~~Authors~~:	+	"A threonine zipper that mediates protein-protein interactions: Structure and prediction".,Oi C, Treado JD, Levine ZA, Lim CS, Knecht KM, Xiong Y, O'Hern CS, Regan L Protein Sci. 2018 Sep 10. doi: 10.1002/pro.3505. PMID:30198622<ref>PMID:30198622</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 6ciu" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Knecht, K M]]
		+	[[Category: Lim, C S]]
		+	[[Category: Oi, C]]
		+	[[Category: Regan, L]]
		+	[[Category: Xiong, Y]]
		+	[[Category: Beta barrel]]
		+	[[Category: Fluorescent protein]]
		+	[[Category: Threonine]]
		+	[[Category: Threonine-rich interface]]

OCA at 06:06, 21 March 2018

OCA — Wed, 21 Mar 2018 06:06:42 GMT

←Older revision		Revision as of 06:06, 21 March 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6ciu is ON HOLD	+	The entry 6ciu is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6ciu" [edit=sysop:move=sysop]

OCA — Thu, 08 Mar 2018 03:46:58 GMT

Protected "6ciu" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:46, 8 March 2018

OCA: New page: '''Unreleased structure''' The entry 6ciu is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 08 Mar 2018 03:46:57 GMT

New page: '''Unreleased structure''' The entry 6ciu is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6ciu is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]