6cxw - Revision history

OCA at 15:13, 4 October 2023

OCA — Wed, 04 Oct 2023 15:13:31 GMT

←Older revision		Revision as of 15:13, 4 October 2023
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	<StructureSection load='6cxw' size='340' side='right'caption='[[6cxw]], [[Resolution\|resolution]] 1.83Å' scene=''>		<StructureSection load='6cxw' size='340' side='right'caption='[[6cxw]], [[Resolution\|resolution]] 1.83Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6cxw]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6CXW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6cxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CXW FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[4wee\|4wee]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.832Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">Syt1 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=10116 Buffalo rat])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxw OCA], [https://pdbe.org/6cxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cxw RCSB], [https://www.ebi.ac.uk/pdbsum/6cxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxw ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6cxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxw OCA], [~~http~~://pdbe.org/6cxw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6cxw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6cxw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxw ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/SYT1_RAT SYT1_RAT]] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.	+	[https://www.uniprot.org/uniprot/SYT1_RAT SYT1_RAT] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
		+
		+	==See Also==
		+	*[[Synaptotagmin 3D structures\|Synaptotagmin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Buffalo rat]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Sutton, R B~~]]	+	[[Category: Rattus norvegicus]]
-	[[Category: ~~C2 domain]]~~	+	[[Category: Sutton RB]]
-	~~[[Category: Exocytosis~~]]	+

OCA at 08:28, 27 November 2019

OCA — Wed, 27 Nov 2019 08:28:39 GMT

←Older revision		Revision as of 08:28, 27 November 2019
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	<StructureSection load='6cxw' size='340' side='right'caption='[[6cxw]], [[Resolution\|resolution]] 1.83Å' scene=''>		<StructureSection load='6cxw' size='340' side='right'caption='[[6cxw]], [[Resolution\|resolution]] 1.83Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6cxw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CXW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6cxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CXW FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wee\|4wee]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wee\|4wee]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Syt1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxw OCA], [http://pdbe.org/6cxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cxw RCSB], [http://www.ebi.ac.uk/pdbsum/6cxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxw OCA], [http://pdbe.org/6cxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cxw RCSB], [http://www.ebi.ac.uk/pdbsum/6cxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxw ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Buffalo rat]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Sutton, R B]]		[[Category: Sutton, R B]]
	[[Category: C2 domain]]		[[Category: C2 domain]]
	[[Category: Exocytosis]]		[[Category: Exocytosis]]

OCA at 05:50, 17 April 2019

OCA — Wed, 17 Apr 2019 05:50:47 GMT

←Older revision		Revision as of 05:50, 17 April 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6cxw is ~~ON HOLD until Paper Publication~~	+	==Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function==
-		+	<StructureSection load='6cxw' size='340' side='right'caption='[[6cxw]], [[Resolution\|resolution]] 1.83Å' scene=''>
-	~~Authors~~: ~~Sutton~~, R.B.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6cxw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CXW FirstGlance]. <br>
-	~~Description~~: ~~Synaptotagmin 1 C2A beta4 chimera~~ with ~~enhanced PIP2 binding function~~	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wee\|4wee]]</td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxw OCA], [http://pdbe.org/6cxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cxw RCSB], [http://www.ebi.ac.uk/pdbsum/6cxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxw ProSAT]</span></td></tr>
-	[[Category: Sutton, R.B]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SYT1_RAT SYT1_RAT]] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Sutton, R B]]
		+	[[Category: C2 domain]]
		+	[[Category: Exocytosis]]

OCA at 05:36, 4 July 2018

OCA — Wed, 04 Jul 2018 05:36:16 GMT

←Older revision		Revision as of 05:36, 4 July 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6cxw is ON HOLD	+	The entry 6cxw is ON HOLD until Paper Publication

	Authors: Sutton, R.B.		Authors: Sutton, R.B.

OCA: Protected "6cxw" [edit=sysop:move=sysop]

OCA — Wed, 11 Apr 2018 12:33:30 GMT

Protected "6cxw" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:33, 11 April 2018

OCA: New page: '''Unreleased structure''' The entry 6cxw is ON HOLD Authors: Sutton, R.B. Description: Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function [[Category: Unreleased Str...

OCA — Wed, 11 Apr 2018 12:33:28 GMT

New page: '''Unreleased structure''' The entry 6cxw is ON HOLD Authors: Sutton, R.B. Description: Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function [[Category: Unreleased Str...

New page

'''Unreleased structure'''

The entry 6cxw is ON HOLD

Authors: Sutton, R.B.

Description: Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function
[[Category: Unreleased Structures]]
[[Category: Sutton, R.B]]