6cze - Revision history

OCA at 14:31, 13 March 2024

OCA — Wed, 13 Mar 2024 14:31:38 GMT

←Older revision		Revision as of 14:31, 13 March 2024
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	<StructureSection load='6cze' size='340' side='right'caption='[[6cze]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='6cze' size='340' side='right'caption='[[6cze]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6cze]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Myctu Myctu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CZE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6CZE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6cze]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CZE FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=ITT:INOSINE+5-TRIPHOSPHATE'>ITT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3fgn\|3fgn]]~~, [[~~3fpa~~\|~~3fpa]], [[3fmi\|3fmi]], [[3fmf\|3fmf]], [[4wop\|4wop]], [[6cve\|6cve]], [[6cvf\|6cvf]], [[6cvu\|6cvu]], [[6cvv\|6cvv]], [[6czb\|6czb]], [[6czc\|6czc]], [[6czd\|6czd~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ITT:INOSINE+5-TRIPHOSPHATE'>ITT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>bioD, Rv1570, MTCY336.33c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~83332 MYCTU])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cze OCA], [https://pdbe.org/6cze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cze RCSB], [https://www.ebi.ac.uk/pdbsum/6cze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cze ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Dethiobiotin_synthase Dethiobiotin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.3 6.3.3.3]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6cze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cze OCA], [~~http~~://pdbe.org/6cze PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6cze RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6cze PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6cze ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU]] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref>	+	[https://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref>

	==See Also==		==See Also==
Line 19:		Line 17:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Dethiobiotin synthase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Myctu~~]]	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	[[Category: Bruning~~, J B~~]]	+	[[Category: Bruning JB]]
-	[[Category: Polyak~~, S W~~]]	+	[[Category: Polyak SW]]
-	[[Category: Thompson~~, A P~~]]	+	[[Category: Thompson AP]]
-	[[Category: Wegener~~, K L]]~~	+	[[Category: Wegener KL]]
-	~~[[Category: Enzyme]]~~	+
-	~~[[Category: Nucleotide triphosphate binding]]~~	+
-	~~[[Category: Synthetase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 08:48, 8 January 2020

OCA — Wed, 08 Jan 2020 08:48:13 GMT

←Older revision		Revision as of 08:48, 8 January 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6cze is ~~ON HOLD~~ ~~until Paper Publication~~	+	==Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with inosine triphosphate (ITP) - promiscuous binding mode with disordered nucleoside==
		+	<StructureSection load='6cze' size='340' side='right'caption='[[6cze]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6cze]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CZE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CZE FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ITT:INOSINE+5-TRIPHOSPHATE'>ITT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3fgn\|3fgn]], [[3fpa\|3fpa]], [[3fmi\|3fmi]], [[3fmf\|3fmf]], [[4wop\|4wop]], [[6cve\|6cve]], [[6cvf\|6cvf]], [[6cvu\|6cvu]], [[6cvv\|6cvv]], [[6czb\|6czb]], [[6czc\|6czc]], [[6czd\|6czd]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bioD, Rv1570, MTCY336.33c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dethiobiotin_synthase Dethiobiotin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.3 6.3.3.3] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cze OCA], [http://pdbe.org/6cze PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cze RCSB], [http://www.ebi.ac.uk/pdbsum/6cze PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cze ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU]] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref>

-	~~Authors: Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W.~~	+	==See Also==
-		+	*[[Dethiobiotin synthetase 3D structures\|Dethiobiotin synthetase 3D structures]]
-	~~Description~~: ~~Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with inosine triphosphate (ITP) -promiscuous binding mode with disordered nucleoside~~	+	== References ==
-	[[Category: ~~Unreleased~~ Structures]]	+	<references/>
-	[[Category: ~~Polyak, S.W~~]]	+	__TOC__
-	[[Category: Bruning, J.B]]	+	</StructureSection>
-	[[Category: Thompson, A.P]]	+	[[Category: Dethiobiotin synthase]]
-	[[Category: Wegener, K.L]]	+	[[Category: Large Structures]]
		+	[[Category: Myctu]]
		+	[[Category: Bruning, J B]]
		+	[[Category: Polyak, S W]]
		+	[[Category: Thompson, A P]]
		+	[[Category: Wegener, K L]]
		+	[[Category: Enzyme]]
		+	[[Category: Nucleotide triphosphate binding]]
		+	[[Category: Synthetase]]
		+	[[Category: Transferase]]

OCA at 04:04, 25 April 2018

OCA — Wed, 25 Apr 2018 04:04:25 GMT

←Older revision		Revision as of 04:04, 25 April 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6cze is ON HOLD	+	The entry 6cze is ON HOLD until Paper Publication

	Authors: Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W.		Authors: Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W.

OCA: Protected "6cze" [edit=sysop:move=sysop]

OCA — Wed, 18 Apr 2018 04:15:14 GMT

Protected "6cze" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:15, 18 April 2018

OCA: New page: '''Unreleased structure''' The entry 6cze is ON HOLD Authors: Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W. Description: Crystal structure of Mycobacterium tuberculosis de...

OCA — Wed, 18 Apr 2018 04:15:13 GMT

New page: '''Unreleased structure''' The entry 6cze is ON HOLD Authors: Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W. Description: Crystal structure of Mycobacterium tuberculosis de...

New page

'''Unreleased structure'''

The entry 6cze is ON HOLD

Authors: Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W.

Description: Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with inosine triphosphate (ITP) -promiscuous binding mode with disordered nucleoside
[[Category: Unreleased Structures]]
[[Category: Polyak, S.W]]
[[Category: Bruning, J.B]]
[[Category: Thompson, A.P]]
[[Category: Wegener, K.L]]