6dd7 - Revision history

OCA at 06:03, 11 October 2023

OCA — Wed, 11 Oct 2023 06:03:23 GMT

←Older revision		Revision as of 06:03, 11 October 2023
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	<StructureSection load='6dd7' size='340' side='right'caption='[[6dd7]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='6dd7' size='340' side='right'caption='[[6dd7]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6dd7]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DD7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6DD7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6dd7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DD7 FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~UVR8~~, ~~At5g63860, MGI19.7 (~~[~~http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=3702 ARATH])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6dd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dd7 OCA], [~~http~~://pdbe.org/6dd7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6dd7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6dd7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6dd7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dd7 OCA], [https://pdbe.org/6dd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dd7 RCSB], [https://www.ebi.ac.uk/pdbsum/6dd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dd7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/UVR8_ARATH UVR8_ARATH]] UV-B specific signaling component that acts as UV-B photoreceptor and plays a key role in establishing UV-protective responses in plants. Upon UV-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, accumulates in the nucleus, interacts with the photomorphogenic repressor COP1 and regulates the expression of the transcription factor HY5 by associating with chromatin (through histone H2B binding) in the HY5 promoter region. UVR8 is involved in controlling aspects of leaf growth and morphogenesis in response to UV-B, is required for normal progression of endocycle and has a regulatory role in stomatal differentiation. Is required for plant circadian clock response to photomorphogenic UV-B light, partly through the transcriptional activation of responsive clock genes. Promotes photosynthetic efficiency at elevated levels of UV-B. Plays a role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway. The two tryptophans, Trp-285 and Trp-233, serve collectively as the UV-B chromophore.<ref>PMID:16330762</ref> <ref>PMID:17720867</ref> <ref>PMID:18055587</ref> <ref>PMID:19165148</ref> <ref>PMID:19402876</ref> <ref>PMID:21041653</ref> <ref>PMID:21395889</ref> <ref>PMID:21454788</ref> <ref>PMID:22447155</ref> <ref>PMID:23161229</ref> <ref>PMID:23012433</ref> <ref>PMID:22988111</ref>	+	[https://www.uniprot.org/uniprot/UVR8_ARATH UVR8_ARATH] UV-B specific signaling component that acts as UV-B photoreceptor and plays a key role in establishing UV-protective responses in plants. Upon UV-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, accumulates in the nucleus, interacts with the photomorphogenic repressor COP1 and regulates the expression of the transcription factor HY5 by associating with chromatin (through histone H2B binding) in the HY5 promoter region. UVR8 is involved in controlling aspects of leaf growth and morphogenesis in response to UV-B, is required for normal progression of endocycle and has a regulatory role in stomatal differentiation. Is required for plant circadian clock response to photomorphogenic UV-B light, partly through the transcriptional activation of responsive clock genes. Promotes photosynthetic efficiency at elevated levels of UV-B. Plays a role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway. The two tryptophans, Trp-285 and Trp-233, serve collectively as the UV-B chromophore.<ref>PMID:16330762</ref> <ref>PMID:17720867</ref> <ref>PMID:18055587</ref> <ref>PMID:19165148</ref> <ref>PMID:19402876</ref> <ref>PMID:21041653</ref> <ref>PMID:21395889</ref> <ref>PMID:21454788</ref> <ref>PMID:22447155</ref> <ref>PMID:23161229</ref> <ref>PMID:23012433</ref> <ref>PMID:22988111</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ren, Z]]	+	[[Category: Ren Z]]
-	~~[[Category: Gene regulation]]~~	+
-	~~[[Category: In situ diffraction]]~~	+
-	~~[[Category: Laue diffraction]]~~	+
-	~~[[Category: Photoreceptor]]~~	+
-	~~[[Category: Serial crystallography~~]]	+

OCA at 17:54, 11 December 2019

OCA — Wed, 11 Dec 2019 17:54:17 GMT

←Older revision		Revision as of 17:54, 11 December 2019
Line 1:		Line 1:

	==Crystal structure of plant UVB photoreceptor UVR8 from in situ serial Laue diffraction==		==Crystal structure of plant UVB photoreceptor UVR8 from in situ serial Laue diffraction==
-	<StructureSection load='6dd7' size='340' side='right' caption='[[6dd7]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='6dd7' size='340' side='right'caption='[[6dd7]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6dd7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DD7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[6dd7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DD7 FirstGlance]. <br>
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Arath]]		[[Category: Arath]]
		+	[[Category: Large Structures]]
	[[Category: Ren, Z]]		[[Category: Ren, Z]]
	[[Category: Gene regulation]]		[[Category: Gene regulation]]

OCA at 22:12, 9 August 2018

OCA — Thu, 09 Aug 2018 22:12:02 GMT

←Older revision		Revision as of 22:12, 9 August 2018
Line 3:		Line 3:
	<StructureSection load='6dd7' size='340' side='right' caption='[[6dd7]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='6dd7' size='340' side='right' caption='[[6dd7]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6dd7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DD7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6dd7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DD7 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dd7 OCA], [http://pdbe.org/6dd7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dd7 RCSB], [http://www.ebi.ac.uk/pdbsum/6dd7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dd7 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">UVR8, At5g63860, MGI19.7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dd7 OCA], [http://pdbe.org/6dd7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dd7 RCSB], [http://www.ebi.ac.uk/pdbsum/6dd7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dd7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arath]]
	[[Category: Ren, Z]]		[[Category: Ren, Z]]
	[[Category: Gene regulation]]		[[Category: Gene regulation]]

OCA at 07:38, 18 July 2018

OCA — Wed, 18 Jul 2018 07:38:45 GMT

←Older revision		Revision as of 07:38, 18 July 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6dd7 is ~~ON HOLD~~	+	==Crystal structure of plant UVB photoreceptor UVR8 from in situ serial Laue diffraction==
		+	<StructureSection load='6dd7' size='340' side='right' caption='[[6dd7]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6dd7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DD7 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dd7 OCA], [http://pdbe.org/6dd7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dd7 RCSB], [http://www.ebi.ac.uk/pdbsum/6dd7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dd7 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/UVR8_ARATH UVR8_ARATH]] UV-B specific signaling component that acts as UV-B photoreceptor and plays a key role in establishing UV-protective responses in plants. Upon UV-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, accumulates in the nucleus, interacts with the photomorphogenic repressor COP1 and regulates the expression of the transcription factor HY5 by associating with chromatin (through histone H2B binding) in the HY5 promoter region. UVR8 is involved in controlling aspects of leaf growth and morphogenesis in response to UV-B, is required for normal progression of endocycle and has a regulatory role in stomatal differentiation. Is required for plant circadian clock response to photomorphogenic UV-B light, partly through the transcriptional activation of responsive clock genes. Promotes photosynthetic efficiency at elevated levels of UV-B. Plays a role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway. The two tryptophans, Trp-285 and Trp-233, serve collectively as the UV-B chromophore.<ref>PMID:16330762</ref> <ref>PMID:17720867</ref> <ref>PMID:18055587</ref> <ref>PMID:19165148</ref> <ref>PMID:19402876</ref> <ref>PMID:21041653</ref> <ref>PMID:21395889</ref> <ref>PMID:21454788</ref> <ref>PMID:22447155</ref> <ref>PMID:23161229</ref> <ref>PMID:23012433</ref> <ref>PMID:22988111</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Recent developments in serial crystallography at X-ray free electron lasers (XFELs) and synchrotrons have been driven by two scientific goals in structural biology - first, static structure determination from nano or microcrystals of membrane proteins and large complexes that are difficult for conventional cryocrystallography, and second, direct observations of transient structural species in biochemical reactions at near atomic resolution. Since room-temperature diffraction experiments naturally demand a large quantity of purified protein, sample economy is critically important for all steps of serial crystallography from crystallization, crystal delivery to data collection. Here we report the development and applications of "crystal-on-crystal" devices to facilitate large-scale in situ serial diffraction experiments on protein crystals of all sizes - large, small, or microscopic. We show that the monocrystalline quartz as a substrate material prevents vapor loss during crystallization and significantly reduces background X-ray scattering. These devices can be readily adopted at XFEL and synchrotron beamlines, which enable efficient delivery of hundreds to millions of crystals to the X-ray beam, with an overall protein consumption per dataset comparable to that of cryocrystallography.

-	~~Authors: Ren~~, Z.	+	Crystal-on-crystal chips for in situ serial diffraction at room temperature.,Ren Z, Ayhan M, Bandara S, Bowatte K, Kumarapperuma I, Gunawardana S, Shin H, Wang C, Zeng X, Yang X Lab Chip. 2018 Jun 28. doi: 10.1039/c8lc00489g. PMID:29952383<ref>PMID:29952383</ref>

-	~~Description: Crystal structure~~ of ~~plant UVB photoreceptor UVR8 from in situ serial Laue diffraction~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 6dd7" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Ren, Z]]		[[Category: Ren, Z]]
		+	[[Category: Gene regulation]]
		+	[[Category: In situ diffraction]]
		+	[[Category: Laue diffraction]]
		+	[[Category: Photoreceptor]]
		+	[[Category: Serial crystallography]]

OCA: Protected "6dd7" [edit=sysop:move=sysop]

OCA — Wed, 16 May 2018 04:09:12 GMT

Protected "6dd7" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:09, 16 May 2018

OCA: New page: '''Unreleased structure''' The entry 6dd7 is ON HOLD Authors: Ren, Z. Description: Crystal structure of plant UVB photoreceptor UVR8 from in situ serial Laue diffraction [[Category: Un...

OCA — Wed, 16 May 2018 04:09:11 GMT

New page: '''Unreleased structure''' The entry 6dd7 is ON HOLD Authors: Ren, Z. Description: Crystal structure of plant UVB photoreceptor UVR8 from in situ serial Laue diffraction [[Category: Un...

New page

'''Unreleased structure'''

The entry 6dd7 is ON HOLD

Authors: Ren, Z.

Description: Crystal structure of plant UVB photoreceptor UVR8 from in situ serial Laue diffraction
[[Category: Unreleased Structures]]
[[Category: Ren, Z]]