6dly - Revision history

OCA at 06:09, 11 October 2023

OCA — Wed, 11 Oct 2023 06:09:11 GMT

←Older revision		Revision as of 06:09, 11 October 2023
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	<StructureSection load='6dly' size='340' side='right'caption='[[6dly]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='6dly' size='340' side='right'caption='[[6dly]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6dly]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Mycmm Mycmm~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6DLY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6dly]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_marinum_M Mycobacterium marinum M] and [https://en.wikipedia.org/wiki/Streptomyces_muensis Streptomyces muensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DLY FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=EDO:1~~,2~~-ETHANEDIOL'>EDO</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=NZC:N-METHYLIDENE-L-THREONINE'>NZC</scene>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=NZC:N-METHYLIDENE-L-THREONINE'>NZC</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dnaN, MMAR_0002 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216594 MYCMM])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dly OCA], [https://pdbe.org/6dly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dly RCSB], [https://www.ebi.ac.uk/pdbsum/6dly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dly ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6dly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dly OCA], [~~http~~://pdbe.org/6dly PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6dly RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6dly PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6dly ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/B2HI47_MYCMM B2HI47_MYCMM]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]	+	[https://www.uniprot.org/uniprot/B2HI47_MYCMM B2HI47_MYCMM] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Mycmm~~]]	+	[[Category: Mycobacterium marinum M]]
-	[[Category: ~~Structural genomic]]~~	+	[[Category: Streptomyces muensis]]
-	~~[[Category: Dna polymerase iii subunit beta]]~~	+
-	~~[[Category: Ssgcid]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 12:29, 17 July 2019

OCA — Wed, 17 Jul 2019 12:29:39 GMT

←Older revision		Revision as of 12:29, 17 July 2019
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	<StructureSection load='6dly' size='340' side='right'caption='[[6dly]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='6dly' size='340' side='right'caption='[[6dly]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6dly]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DLY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6dly]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycmm Mycmm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DLY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=NZC:N-METHYLIDENE-L-THREONINE'>NZC</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=NZC:N-METHYLIDENE-L-THREONINE'>NZC</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dnaN, MMAR_0002 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216594 MYCMM])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dly OCA], [http://pdbe.org/6dly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dly RCSB], [http://www.ebi.ac.uk/pdbsum/6dly PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dly ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dly OCA], [http://pdbe.org/6dly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dly RCSB], [http://www.ebi.ac.uk/pdbsum/6dly PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dly ProSAT]</span></td></tr>
	</table>		</table>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Mycmm]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Dna polymerase iii subunit beta]]		[[Category: Dna polymerase iii subunit beta]]
	[[Category: Ssgcid]]		[[Category: Ssgcid]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 05:29, 12 June 2019

OCA — Wed, 12 Jun 2019 05:29:22 GMT

←Older revision		Revision as of 05:29, 12 June 2019
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-	'''Unreleased structure'''

-	~~The entry 6dly is ON HOLD until Paper Publication~~	+	==Crystal structure of DNA polymerase III subunit beta from Mycobacterium marinum in complex with a natural product==
-		+	<StructureSection load='6dly' size='340' side='right'caption='[[6dly]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6dly]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DLY FirstGlance]. <br>
-	~~Description:~~ Crystal structure of DNA polymerase III subunit beta from Mycobacterium marinum in complex with a natural product	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=MLU:N-METHYL-D-LEUCINE'>MLU</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=NZC:N-METHYLIDENE-L-THREONINE'>NZC</scene></td></tr>
-	[[Category: ~~Seattle~~ Structural ~~Genomics Center For Infectious Disease (~~Ssgcid)]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dly OCA], [http://pdbe.org/6dly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dly RCSB], [http://www.ebi.ac.uk/pdbsum/6dly PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dly ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/B2HI47_MYCMM B2HI47_MYCMM]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Structural genomic]]
		+	[[Category: Dna polymerase iii subunit beta]]
		+	[[Category: Ssgcid]]
		+	[[Category: Transferase]]

OCA at 04:11, 29 May 2019

OCA — Wed, 29 May 2019 04:11:43 GMT

←Older revision		Revision as of 04:11, 29 May 2019
Line 5:		Line 5:
	Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)		Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

-	Description: ~~CRYSTAL STRUCTURE OF A~~ DNA ~~POLYMERASE~~ III ~~SUBUNIT BETA FROM MYCOBACTERIUM MARINUM IN COMPLEX WITH A NATURAL PRODUCT~~	+	Description: Crystal structure of DNA polymerase III subunit beta from Mycobacterium marinum in complex with a natural product
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]		[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]

OCA at 05:37, 4 July 2018

OCA — Wed, 04 Jul 2018 05:37:14 GMT

←Older revision		Revision as of 05:37, 4 July 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6dly is ON HOLD	+	The entry 6dly is ON HOLD until Paper Publication

	Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)		Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

OCA: Protected "6dly" [edit=sysop:move=sysop]

OCA — Thu, 14 Jun 2018 05:41:33 GMT

Protected "6dly" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:41, 14 June 2018

OCA: New page: '''Unreleased structure''' The entry 6dly is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: CRYSTAL STRUCTURE OF A DNA POLYMERASE III ...

OCA — Thu, 14 Jun 2018 05:41:32 GMT

New page: '''Unreleased structure''' The entry 6dly is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Description: CRYSTAL STRUCTURE OF A DNA POLYMERASE III ...

New page

'''Unreleased structure'''

The entry 6dly is ON HOLD

Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Description: CRYSTAL STRUCTURE OF A DNA POLYMERASE III SUBUNIT BETA FROM MYCOBACTERIUM MARINUM IN COMPLEX WITH A NATURAL PRODUCT
[[Category: Unreleased Structures]]
[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]