6e0p - Revision history

OCA at 00:16, 11 April 2020

OCA — Sat, 11 Apr 2020 00:16:33 GMT

←Older revision		Revision as of 00:16, 11 April 2020
Line 3:		Line 3:
	<SX load='6e0p' size='340' side='right' viewer='molstar' caption='[[6e0p]], [[Resolution\|resolution]] 2.60Å' scene=''>		<SX load='6e0p' size='340' side='right' viewer='molstar' caption='[[6e0p]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6e0p]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0P OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6E0P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6e0p]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0P OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6E0P FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CENPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H2AB, H2AFM, HIST1H2AE, H2AFA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H2BJ, H2BFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CENPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H2AB, H2AFM, HIST1H2AE, H2AFA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H2BJ, H2BFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6e0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e0p OCA], [http://pdbe.org/6e0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e0p RCSB], [http://www.ebi.ac.uk/pdbsum/6e0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e0p ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6e0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e0p OCA], [http://pdbe.org/6e0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e0p RCSB], [http://www.ebi.ac.uk/pdbsum/6e0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e0p ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 20:59, 6 March 2020

OCA — Fri, 06 Mar 2020 20:59:38 GMT

←Older revision		Revision as of 20:59, 6 March 2020
Line 1:		Line 1:

	==Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment==		==Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment==
-	<~~StructureSection~~ load='6e0p' size='340' side='right'caption='[[6e0p]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<SX load='6e0p' size='340' side='right' viewer='molstar' caption='[[6e0p]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6e0p]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E0P FirstGlance]. <br>		<table><tr><td colspan='2'>[[6e0p]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E0P FirstGlance]. <br>
Line 21:		Line 21:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Human]]		[[Category: Human]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 06:09, 12 June 2019

OCA — Wed, 12 Jun 2019 06:09:34 GMT

←Older revision		Revision as of 06:09, 12 June 2019
Line 3:		Line 3:
	<StructureSection load='6e0p' size='340' side='right'caption='[[6e0p]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='6e0p' size='340' side='right'caption='[[6e0p]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6e0p]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E0P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6e0p]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E0P FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e0p OCA], [http://pdbe.org/6e0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e0p RCSB], [http://www.ebi.ac.uk/pdbsum/6e0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e0p ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CENPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H2AB, H2AFM, HIST1H2AE, H2AFA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H2BJ, H2BFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e0p OCA], [http://pdbe.org/6e0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e0p RCSB], [http://www.ebi.ac.uk/pdbsum/6e0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e0p ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> [[http://www.uniprot.org/uniprot/CENPA_HUMAN CENPA_HUMAN]] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).<ref>PMID:20739937</ref> <ref>PMID:21478274</ref>		[[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> [[http://www.uniprot.org/uniprot/CENPA_HUMAN CENPA_HUMAN]] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).<ref>PMID:20739937</ref> <ref>PMID:21478274</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Genomic DNA in eukaryotes is organized into chromatin through association with core histones to form nucleosomes, each distinguished by their DNA sequences and histone variants. Here, we used a single-chain antibody fragment (scFv) derived from the anti-nucleosome antibody mAb PL2-6 to stabilize human CENP-A nucleosome containing a native alpha-satellite DNA and solved its structure by the cryo-electron microscopy (cryo-EM) to 2.6 A resolution. In comparison, the corresponding cryo-EM structure of the free CENP-A nucleosome could only reach 3.4 A resolution. We find that scFv binds to a conserved acidic patch on the histone H2A-H2B dimer without perturbing the nucleosome structure. Our results provide an atomic resolution cryo-EM structure of a nucleosome and insight into the structure and function of the CENP-A nucleosome. The scFv approach is applicable to the structural determination of other native-like nucleosomes with distinct DNA sequences.
		+
		+	Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment.,Zhou BR, Yadav KNS, Borgnia M, Hong J, Cao B, Olins AL, Olins DE, Bai Y, Zhang P Nat Commun. 2019 May 24;10(1):2301. doi: 10.1038/s41467-019-10247-4. PMID:31127102<ref>PMID:31127102</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6e0p" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
		+	[[Category: Lk3 transgenic mice]]
	[[Category: Yadav, K N.S]]		[[Category: Yadav, K N.S]]
	[[Category: Zhou, B R]]		[[Category: Zhou, B R]]

OCA at 06:44, 23 May 2019

OCA — Thu, 23 May 2019 06:44:22 GMT

←Older revision		Revision as of 06:44, 23 May 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 6e0p is ON HOLD until Paper Publication~~	+	==Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment==
-		+	<StructureSection load='6e0p' size='340' side='right'caption='[[6e0p]], [[Resolution\|resolution]] 2.60Å' scene=''>
-	~~Authors: Yadav, K.N.S., Zhou, B.-R.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6e0p]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E0P FirstGlance]. <br>
-	~~Description:~~ Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e0p OCA], [http://pdbe.org/6e0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e0p RCSB], [http://www.ebi.ac.uk/pdbsum/6e0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e0p ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
-	[[Category: Yadav, K.N.S]]	+	== Function ==
-	[[Category: Zhou, B.-R]]	+	[[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> [[http://www.uniprot.org/uniprot/CENPA_HUMAN CENPA_HUMAN]] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).<ref>PMID:20739937</ref> <ref>PMID:21478274</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Yadav, K N.S]]
		+	[[Category: Zhou, B R]]
		+	[[Category: Acidic patch]]
		+	[[Category: Anti-nucleosome antibody]]
		+	[[Category: Cenp-a]]
		+	[[Category: Centromere]]
		+	[[Category: Native alpha satellite dna]]
		+	[[Category: Nuclear protein]]
		+	[[Category: Nucleosome]]

OCA at 05:34, 21 May 2019

OCA — Tue, 21 May 2019 05:34:05 GMT

←Older revision		Revision as of 05:34, 21 May 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6e0p is ON HOLD	+	The entry 6e0p is ON HOLD until Paper Publication

	Authors: Yadav, K.N.S., Zhou, B.-R.		Authors: Yadav, K.N.S., Zhou, B.-R.

OCA at 13:28, 27 February 2019

OCA — Wed, 27 Feb 2019 13:28:38 GMT

←Older revision		Revision as of 13:28, 27 February 2019
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6e0p is ON HOLD ~~until Paper Publication~~	+	The entry 6e0p is ON HOLD

	Authors: Yadav, K.N.S., Zhou, B.-R.		Authors: Yadav, K.N.S., Zhou, B.-R.
Line 7:		Line 7:
	Description: Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment		Description: Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Zhou, B.-R]]
	[[Category: Yadav, K.N.S]]		[[Category: Yadav, K.N.S]]
		+	[[Category: Zhou, B.-R]]

OCA at 05:06, 31 October 2018

OCA — Wed, 31 Oct 2018 05:06:24 GMT

←Older revision		Revision as of 05:06, 31 October 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6e0p is ON HOLD	+	The entry 6e0p is ON HOLD until Paper Publication

	Authors: Yadav, K.N.S., Zhou, B.-R.		Authors: Yadav, K.N.S., Zhou, B.-R.
Line 7:		Line 7:
	Description: Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment		Description: Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Yadav, K.N.S]]
	[[Category: Zhou, B.-R]]		[[Category: Zhou, B.-R]]
		+	[[Category: Yadav, K.N.S]]

OCA at 04:07, 24 October 2018

OCA — Wed, 24 Oct 2018 04:07:00 GMT

←Older revision		Revision as of 04:07, 24 October 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6e0p is ON HOLD ~~until Paper Publication~~	+	The entry 6e0p is ON HOLD

	Authors: Yadav, K.N.S., Zhou, B.-R.		Authors: Yadav, K.N.S., Zhou, B.-R.

OCA at 06:09, 10 October 2018

OCA — Wed, 10 Oct 2018 06:09:08 GMT

←Older revision		Revision as of 06:09, 10 October 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6e0p is ON HOLD	+	The entry 6e0p is ON HOLD until Paper Publication

	Authors: Yadav, K.N.S., Zhou, B.-R.		Authors: Yadav, K.N.S., Zhou, B.-R.
Line 7:		Line 7:
	Description: Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment		Description: Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Zhou, B.-R]]
	[[Category: Yadav, K.N.S]]		[[Category: Yadav, K.N.S]]
		+	[[Category: Zhou, B.-R]]

OCA: Protected "6e0p" [edit=sysop:move=sysop]

OCA — Wed, 18 Jul 2018 05:33:11 GMT

Protected "6e0p" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:33, 18 July 2018