6e9x - Revision history

OCA at 14:40, 13 March 2024

OCA — Wed, 13 Mar 2024 14:40:17 GMT

←Older revision		Revision as of 14:40, 13 March 2024
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	<SX load='6e9x' size='340' side='right' viewer='molstar' caption='[[6e9x]], [[Resolution\|resolution]] 7.80Å' scene=''>		<SX load='6e9x' size='340' side='right' viewer='molstar' caption='[[6e9x]], [[Resolution\|resolution]] 7.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6e9x]] is a 21 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Synthetic_construct_sequences~~ Synthetic construct ~~sequences~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E9X OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6E9X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6e9x]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E9X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6E9X FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6e9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e9x OCA], [~~http~~://pdbe.org/6e9x PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6e9x RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6e9x PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6e9x ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 7.8Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6e9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e9x OCA], [https://pdbe.org/6e9x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6e9x RCSB], [https://www.ebi.ac.uk/pdbsum/6e9x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6e9x ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	We describe a general computational approach to designing self-assembling helical filaments from monomeric proteins and use this approach to design proteins that assemble into micrometer-scale filaments with a wide range of geometries in vivo and in vitro. Cryo-electron microscopy structures of six designs are close to the computational design models. The filament building blocks are idealized repeat proteins, and thus the diameter of the filaments can be systematically tuned by varying the number of repeat units. The assembly and disassembly of the filaments can be controlled by engineered anchor and capping units built from monomers lacking one of the interaction surfaces. The ability to generate dynamic, highly ordered structures that span micrometers from protein monomers opens up possibilities for the fabrication of new multiscale metamaterials.
-
-	De novo design of self-assembling helical protein filaments.,Shen H, Fallas JA, Lynch E, Sheffler W, Parry B, Jannetty N, Decarreau J, Wagenbach M, Vicente JJ, Chen J, Wang L, Dowling Q, Oberdorfer G, Stewart L, Wordeman L, De Yoreo J, Jacobs-Wagner C, Kollman J, Baker D Science. 2018 Nov 9;362(6415):705-709. doi: 10.1126/science.aau3775. PMID:30409885<ref>PMID:30409885</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 6e9x" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</SX>		</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Synthetic construct ~~sequences~~]]	+	[[Category: Synthetic construct]]
-	[[Category: Baker, D]]	+	[[Category: Baker D]]
-	[[Category: Fallas~~, J A~~]]	+	[[Category: Fallas JA]]
-	[[Category: Kollman~~, J M~~]]	+	[[Category: Kollman JM]]
-	[[Category: Lynch~~, E M~~]]	+	[[Category: Lynch EM]]
-	[[Category: Shen, H]]	+	[[Category: Shen H]]
-	~~[[Category: Filament]]~~	+
-	~~[[Category: Protein design]]~~	+
-	~~[[Category: Protein fibril~~]]	+

OCA at 00:22, 11 April 2020

OCA — Sat, 11 Apr 2020 00:22:39 GMT

←Older revision		Revision as of 00:22, 11 April 2020
Line 3:		Line 3:
	<SX load='6e9x' size='340' side='right' viewer='molstar' caption='[[6e9x]], [[Resolution\|resolution]] 7.80Å' scene=''>		<SX load='6e9x' size='340' side='right' viewer='molstar' caption='[[6e9x]], [[Resolution\|resolution]] 7.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6e9x]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E9X OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6E9X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6e9x]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E9X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6E9X FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6e9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e9x OCA], [http://pdbe.org/6e9x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e9x RCSB], [http://www.ebi.ac.uk/pdbsum/6e9x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e9x ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6e9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e9x OCA], [http://pdbe.org/6e9x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e9x RCSB], [http://www.ebi.ac.uk/pdbsum/6e9x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e9x ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 21:03, 6 March 2020

OCA — Fri, 06 Mar 2020 21:03:50 GMT

←Older revision		Revision as of 21:03, 6 March 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6e9x is ~~ON HOLD until Paper~~ Publication	+	==DHF91 filament==
		+	<SX load='6e9x' size='340' side='right' viewer='molstar' caption='[[6e9x]], [[Resolution\|resolution]] 7.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6e9x]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E9X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E9X FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e9x OCA], [http://pdbe.org/6e9x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e9x RCSB], [http://www.ebi.ac.uk/pdbsum/6e9x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e9x ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We describe a general computational approach to designing self-assembling helical filaments from monomeric proteins and use this approach to design proteins that assemble into micrometer-scale filaments with a wide range of geometries in vivo and in vitro. Cryo-electron microscopy structures of six designs are close to the computational design models. The filament building blocks are idealized repeat proteins, and thus the diameter of the filaments can be systematically tuned by varying the number of repeat units. The assembly and disassembly of the filaments can be controlled by engineered anchor and capping units built from monomers lacking one of the interaction surfaces. The ability to generate dynamic, highly ordered structures that span micrometers from protein monomers opens up possibilities for the fabrication of new multiscale metamaterials.

-	~~Authors~~:	+	De novo design of self-assembling helical protein filaments.,Shen H, Fallas JA, Lynch E, Sheffler W, Parry B, Jannetty N, Decarreau J, Wagenbach M, Vicente JJ, Chen J, Wang L, Dowling Q, Oberdorfer G, Stewart L, Wordeman L, De Yoreo J, Jacobs-Wagner C, Kollman J, Baker D Science. 2018 Nov 9;362(6415):705-709. doi: 10.1126/science.aau3775. PMID:30409885<ref>PMID:30409885</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased~~ Structures]]	+	</div>
		+	<div class="pdbe-citations 6e9x" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</SX>
		+	[[Category: Large Structures]]
		+	[[Category: Synthetic construct sequences]]
		+	[[Category: Baker, D]]
		+	[[Category: Fallas, J A]]
		+	[[Category: Kollman, J M]]
		+	[[Category: Lynch, E M]]
		+	[[Category: Shen, H]]
		+	[[Category: Filament]]
		+	[[Category: Protein design]]
		+	[[Category: Protein fibril]]

OCA at 06:09, 17 October 2018

OCA — Wed, 17 Oct 2018 06:09:40 GMT

←Older revision		Revision as of 06:09, 17 October 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6e9x is ON HOLD	+	The entry 6e9x is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6e9x" [edit=sysop:move=sysop]

OCA — Thu, 09 Aug 2018 19:57:56 GMT

Protected "6e9x" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:57, 9 August 2018

OCA: New page: '''Unreleased structure''' The entry 6e9x is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 09 Aug 2018 19:57:55 GMT

New page: '''Unreleased structure''' The entry 6e9x is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6e9x is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]