6evu - Revision history

OCA at 12:22, 9 May 2024

OCA — Thu, 09 May 2024 12:22:05 GMT

←Older revision		Revision as of 12:22, 9 May 2024
Line 1:		Line 1:

	==Adhesin domain of PrgB from Enterococcus faecalis==		==Adhesin domain of PrgB from Enterococcus faecalis==
-	<StructureSection load='6evu' size='340' side='right' caption='[[6evu]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='6evu' size='340' side='right'caption='[[6evu]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6evu]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EVU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6EVU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6evu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EVU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EVU FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=PO4:PHOSPHATE+ION'>PO4</scene~~>, ~~<scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-~~1~~,3-DIOL'>TRS</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.598Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~prgB ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode=5&id~~=~~1351 "Enterococcus proteiformis" Thiercelin and Jouhaud 1903])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6evu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6evu OCA], [~~http~~://pdbe.org/6evu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6evu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6evu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6evu ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6evu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6evu OCA], [https://pdbe.org/6evu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6evu RCSB], [https://www.ebi.ac.uk/pdbsum/6evu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6evu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q04112_ENTFL Q04112_ENTFL]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Enterococcus ~~proteiformis thiercelin and jouhaud 1903~~]]	+	[[Category: Enterococcus faecalis]]
-	[[Category: ~~Berntsson, R P.A~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Schmitt, A~~]]	+	[[Category: Berntsson RPA]]
-	[[Category: ~~Adhesin]]~~	+	[[Category: Schmitt A]]
-	~~[[Category: Biofilm formation]]~~	+
-	~~[[Category: Cell adhesion~~]]	+

OCA at 08:49, 3 October 2018

OCA — Wed, 03 Oct 2018 08:49:46 GMT

←Older revision		Revision as of 08:49, 3 October 2018
Line 3:		Line 3:
	<StructureSection load='6evu' size='340' side='right' caption='[[6evu]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='6evu' size='340' side='right' caption='[[6evu]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6evu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EVU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EVU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6evu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EVU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EVU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">prgB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1351 "Enterococcus proteiformis" Thiercelin and Jouhaud 1903])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6evu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6evu OCA], [http://pdbe.org/6evu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6evu RCSB], [http://www.ebi.ac.uk/pdbsum/6evu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6evu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6evu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6evu OCA], [http://pdbe.org/6evu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6evu RCSB], [http://www.ebi.ac.uk/pdbsum/6evu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6evu ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]]
	[[Category: Berntsson, R P.A]]		[[Category: Berntsson, R P.A]]
	[[Category: Schmitt, A]]		[[Category: Schmitt, A]]

OCA at 05:34, 16 May 2018

OCA — Wed, 16 May 2018 05:34:56 GMT

←Older revision		Revision as of 05:34, 16 May 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6evu is ~~ON HOLD until Paper~~ Publication	+	==Adhesin domain of PrgB from Enterococcus faecalis==
		+	<StructureSection load='6evu' size='340' side='right' caption='[[6evu]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6evu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EVU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EVU FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6evu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6evu OCA], [http://pdbe.org/6evu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6evu RCSB], [http://www.ebi.ac.uk/pdbsum/6evu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6evu ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Gram-positive bacteria deploy type IV secretion systems (T4SSs) to facilitate horizontal gene transfer. The T4SSs of Gram-positive bacteria rely on surface adhesins as opposed to conjugative pili to facilitate mating. Enterococcus faecalis PrgB is a surface adhesin that promotes mating pair formation and robust biofilm development in an extracellular DNA (eDNA) dependent manner. Here we report the structure of the adhesin domain of PrgB. The adhesin domain binds and compacts DNA in vitro. In vivo PrgB deleted of its adhesin domain does not support cellular aggregation, biofilm development and conjugative DNA transfer. PrgB also binds lipoteichoic acid (LTA), which competes with DNA binding. We propose that PrgB binding and compaction of eDNA facilitates cell aggregation and plays an important role in establishment of early biofilms in mono- or polyspecies settings. Within these biofilms, PrgB mediates formation and stabilization of direct cell-cell contacts through alternative binding of cell-bound LTA, which in turn promotes establishment of productive mating junctions and efficient intra- or interspecies T4SS-mediated gene transfer. This article is protected by copyright. All rights reserved.

-	~~Authors~~:	+	PrgB Promotes Aggregation, Biofilm Formation, and Conjugation through DNA Binding and Compaction.,Schmitt A, Jiang K, Camacho MI, Jonna VR, Hofer A, Westerlund F, Christie PJ, Berntsson RP Mol Microbiol. 2018 May 3. doi: 10.1111/mmi.13980. PMID:29723434<ref>PMID:29723434</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 6evu" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Berntsson, R P.A]]
		+	[[Category: Schmitt, A]]
		+	[[Category: Adhesin]]
		+	[[Category: Biofilm formation]]
		+	[[Category: Cell adhesion]]

OCA at 06:28, 15 November 2017

OCA — Wed, 15 Nov 2017 06:28:19 GMT

←Older revision		Revision as of 06:28, 15 November 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6evu is ON HOLD	+	The entry 6evu is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6evu" [edit=sysop:move=sysop]

OCA — Wed, 08 Nov 2017 06:45:41 GMT

Protected "6evu" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:45, 8 November 2017

OCA: New page: '''Unreleased structure''' The entry 6evu is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 08 Nov 2017 06:45:39 GMT

New page: '''Unreleased structure''' The entry 6evu is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6evu is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]