6fu9 - Revision history

OCA at 09:49, 18 July 2018

OCA — Wed, 18 Jul 2018 09:49:51 GMT

←Older revision		Revision as of 09:49, 18 July 2018
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	<StructureSection load='6fu9' size='340' side='right' caption='[[6fu9]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='6fu9' size='340' side='right' caption='[[6fu9]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6fu9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FU9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6fu9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpi_841383 Bpi 841383] and [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FU9 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6fub\|6fub]], [[6fud\|6fud]], [[6g10\|6g10]], [[6g11\|6g11]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6fub\|6fub]], [[6fud\|6fud]], [[6g10\|6g10]], [[6g11\|6g11]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Pikm1-TS, Pi-km1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Japanese rice]), AVR-Pik, AvrPik, Pikm, Pikp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=318829 BPI 841383])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fu9 OCA], [http://pdbe.org/6fu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fu9 RCSB], [http://www.ebi.ac.uk/pdbsum/6fu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fu9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fu9 OCA], [http://pdbe.org/6fu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fu9 RCSB], [http://www.ebi.ac.uk/pdbsum/6fu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fu9 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Accelerated adaptive evolution is a hallmark of plant-pathogen interactions. Plant intracellular immune receptors (NLRs) often occur as allelic series with differential pathogen specificities. The determinants of this specificity remain largely unknown. Here, we unravelled the biophysical and structural basis of expanded specificity in the allelic rice NLR Pik, which responds to the effector AVR-Pik from the rice blast pathogen Magnaporthe oryzae. Rice plants expressing the Pikm allele resist infection by blast strains expressing any of three AVR-Pik effector variants, whereas those expressing Pikp only respond to one. Unlike Pikp, the integrated heavy metal-associated (HMA) domain of Pikm binds with high affinity to each of the three recognized effector variants, and variation at binding interfaces between effectors and Pikp-HMA or Pikm-HMA domains encodes specificity. By understanding how co-evolution has shaped the response profile of an allelic NLR, we highlight how natural selection drove the emergence of new receptor specificities. This work has implications for the engineering of NLRs with improved utility in agriculture.
		+
		+	Polymorphic residues in rice NLRs expand binding and response to effectors of the blast pathogen.,De la Concepcion JC, Franceschetti M, Maqbool A, Saitoh H, Terauchi R, Kamoun S, Banfield MJ Nat Plants. 2018 Jul 9. pii: 10.1038/s41477-018-0194-x. doi:, 10.1038/s41477-018-0194-x. PMID:29988155<ref>PMID:29988155</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6fu9" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bpi 841383]]
		+	[[Category: Japanese rice]]
	[[Category: Banfield, M J]]		[[Category: Banfield, M J]]
	[[Category: Concepcion, J C.De la]]		[[Category: Concepcion, J C.De la]]

OCA at 07:42, 14 June 2018

OCA — Thu, 14 Jun 2018 07:42:29 GMT

←Older revision		Revision as of 07:42, 14 June 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6fu9 is ~~ON HOLD until Paper Publication~~	+	==Complex of rice blast (Magnaporthe oryzae) effector protein AVR-PikD with the HMA domain of Pikm-1 from rice (Oryza sativa)==
-		+	<StructureSection load='6fu9' size='340' side='right' caption='[[6fu9]], [[Resolution\|resolution]] 1.20Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6fu9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FU9 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6fub\|6fub]], [[6fud\|6fud]], [[6g10\|6g10]], [[6g11\|6g11]]</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fu9 OCA], [http://pdbe.org/6fu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fu9 RCSB], [http://www.ebi.ac.uk/pdbsum/6fu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fu9 ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Banfield, M J]]
		+	[[Category: Concepcion, J C.De la]]
		+	[[Category: Franceschetti, M]]
		+	[[Category: Antifungal protein]]
		+	[[Category: Complex]]
		+	[[Category: Fungal effector]]
		+	[[Category: Plant immunity]]
		+	[[Category: Plant nlr]]

OCA at 05:13, 14 March 2018

OCA — Wed, 14 Mar 2018 05:13:57 GMT

←Older revision		Revision as of 05:13, 14 March 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6fu9 is ON HOLD	+	The entry 6fu9 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6fu9" [edit=sysop:move=sysop]

OCA — Thu, 08 Mar 2018 03:57:21 GMT

Protected "6fu9" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:57, 8 March 2018

OCA: New page: '''Unreleased structure''' The entry 6fu9 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Thu, 08 Mar 2018 03:57:20 GMT

New page: '''Unreleased structure''' The entry 6fu9 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6fu9 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]