OCA at 05:48, 11 July 2018

OCA — Wed, 11 Jul 2018 05:48:28 GMT

←Older revision		Revision as of 05:48, 11 July 2018
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-	'''Unreleased structure'''

-	~~The entry 6g2n is ON HOLD until Paper Publication~~	+	==Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PAU==
-		+	<StructureSection load='6g2n' size='340' side='right' caption='[[6g2n]], [[Resolution\|resolution]] 1.40Å' scene=''>
-	~~Authors: Pachl, P., Rezacova, P., Brynda, J.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6g2n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G2N FirstGlance]. <br>
-	~~Description:~~ Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PAU	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=O84:[(2~{R},4~{a}~{R},6~{R},7~{a}~{R})-6-[2,4-bis(oxidanylidene)-5-[(~{E})-3-phosphonoprop-1-enyl]pyrimidin-1-yl]-2-phenyl-4~{a},6,7,7~{a}-tetrahydro-4~{H}-furo[3,2-d][1,3]dioxin-2-yl]phosphonic+acid'>O84</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
-	[[~~Category~~: ~~Rezacova~~, P]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6g22\|6g22]], [[6g2l\|6g2l]], [[6g2m\|6g2m]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g2n OCA], [http://pdbe.org/6g2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g2n RCSB], [http://www.ebi.ac.uk/pdbsum/6g2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g2n ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NT5C_HUMAN NT5C_HUMAN]] Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
		+	__TOC__
		+	</StructureSection>
	[[Category: Brynda, J]]		[[Category: Brynda, J]]
	[[Category: Pachl, P]]		[[Category: Pachl, P]]
		+	[[Category: Rezacova, P]]
		+	[[Category: 5'-nucleotidase]]
		+	[[Category: Dephosphorylation]]
		+	[[Category: Had-like]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Mitochondria]]
		+	[[Category: Phosphorylation]]

OCA: Protected "6g2n" [edit=sysop:move=sysop]

OCA — Wed, 04 Apr 2018 04:48:18 GMT

Protected "6g2n" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:48, 4 April 2018

OCA: New page: '''Unreleased structure''' The entry 6g2n is ON HOLD until Paper Publication Authors: Pachl, P., Rezacova, P., Brynda, J. Description: Crystal structure of human cytosolic 5'(3')-deoxy...

OCA — Wed, 04 Apr 2018 04:48:17 GMT

New page: '''Unreleased structure''' The entry 6g2n is ON HOLD until Paper Publication Authors: Pachl, P., Rezacova, P., Brynda, J. Description: Crystal structure of human cytosolic 5'(3')-deoxy...

New page

'''Unreleased structure'''

The entry 6g2n is ON HOLD until Paper Publication

Authors: Pachl, P., Rezacova, P., Brynda, J.

Description: Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PAU
[[Category: Unreleased Structures]]
[[Category: Rezacova, P]]
[[Category: Brynda, J]]
[[Category: Pachl, P]]

6g2n - Revision history

OCA at 05:48, 11 July 2018

OCA: Protected "6g2n" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6g2n is ON HOLD until Paper Publication Authors: Pachl, P., Rezacova, P., Brynda, J. Description: Crystal structure of human cytosolic 5'(3')-deoxy...