6g73 - Revision history

OCA at 13:29, 10 May 2019

OCA — Fri, 10 May 2019 13:29:38 GMT

←Older revision		Revision as of 13:29, 10 May 2019
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	<StructureSection load='6g73' size='340' side='right'caption='[[6g73]], [[Resolution\|resolution]] 3.27Å' scene=''>		<StructureSection load='6g73' size='340' side='right'caption='[[6g73]], [[Resolution\|resolution]] 3.27Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6g73]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G73 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6g73]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G73 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VDAC1, VDAC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g73 OCA], [http://pdbe.org/6g73 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g73 RCSB], [http://www.ebi.ac.uk/pdbsum/6g73 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g73 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g73 OCA], [http://pdbe.org/6g73 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g73 RCSB], [http://www.ebi.ac.uk/pdbsum/6g73 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g73 ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Gribbon, P]]		[[Category: Gribbon, P]]

OCA at 06:40, 24 April 2019

OCA — Wed, 24 Apr 2019 06:40:31 GMT

←Older revision		Revision as of 06:40, 24 April 2019
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-	'''Unreleased structure'''

-	The ~~entry~~ 6g73 is ~~ON HOLD until Paper Publication~~	+	==The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 3.3 Angstrom resolution==
-		+	<StructureSection load='6g73' size='340' side='right'caption='[[6g73]], [[Resolution\|resolution]] 3.27Å' scene=''>
-	~~Authors~~: ~~Razeto~~, A., ~~Gribbon~~, P., ~~Loew~~, C.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6g73]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G73 FirstGlance]. <br>
-	~~Description~~: The ~~dynamic nature~~ of the ~~VDAC1 channels~~ in ~~bilayers: human VDAC1~~ at 3.~~3 Angstrom resolution~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g73 OCA], [http://pdbe.org/6g73 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g73 RCSB], [http://www.ebi.ac.uk/pdbsum/6g73 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g73 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/VDAC1_HUMAN VDAC1_HUMAN]] Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.<ref>PMID:11845315</ref> <ref>PMID:15033708</ref> <ref>PMID:18755977</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Gribbon, P]]		[[Category: Gribbon, P]]
		+	[[Category: Loew, C]]
	[[Category: Razeto, A]]		[[Category: Razeto, A]]
-	[[Category: ~~Loew, C~~]]	+	[[Category: Apoptosis]]
		+	[[Category: B-barrel]]
		+	[[Category: Cytochrome c release]]
		+	[[Category: Ion-channel]]
		+	[[Category: Outer mitochondrial membrane]]
		+	[[Category: Transport protein]]

OCA at 06:51, 2 May 2018

OCA — Wed, 02 May 2018 06:51:13 GMT

←Older revision		Revision as of 06:51, 2 May 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6g73 is ON HOLD	+	The entry 6g73 is ON HOLD until Paper Publication

	Authors: Razeto, A., Gribbon, P., Loew, C.		Authors: Razeto, A., Gribbon, P., Loew, C.

OCA: Protected "6g73" [edit=sysop:move=sysop]

OCA — Wed, 11 Apr 2018 12:41:43 GMT

Protected "6g73" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:41, 11 April 2018

OCA: New page: '''Unreleased structure''' The entry 6g73 is ON HOLD Authors: Razeto, A., Gribbon, P., Loew, C. Description: The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 3.3 An...

OCA — Wed, 11 Apr 2018 12:41:42 GMT

New page: '''Unreleased structure''' The entry 6g73 is ON HOLD Authors: Razeto, A., Gribbon, P., Loew, C. Description: The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 3.3 An...

New page

'''Unreleased structure'''

The entry 6g73 is ON HOLD

Authors: Razeto, A., Gribbon, P., Loew, C.

Description: The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 3.3 Angstrom resolution
[[Category: Unreleased Structures]]
[[Category: Gribbon, P]]
[[Category: Razeto, A]]
[[Category: Loew, C]]