6g7l - Revision history

OCA at 07:39, 25 July 2018

OCA — Wed, 25 Jul 2018 07:39:38 GMT

←Older revision		Revision as of 07:39, 25 July 2018
Line 3:		Line 3:
	<StructureSection load='6g7l' size='340' side='right' caption='[[6g7l]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='6g7l' size='340' side='right' caption='[[6g7l]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6g7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Halobacterium_salinarum_(strain_atcc_700922_/_jcm_11081_/_nrc-1) Halobacterium salinarum (strain atcc 700922 / jcm 11081 / nrc-1)~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G7L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6g7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halsa Halsa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G7L FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g7l OCA], [http://pdbe.org/6g7l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g7l RCSB], [http://www.ebi.ac.uk/pdbsum/6g7l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g7l ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g7l OCA], [http://pdbe.org/6g7l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g7l RCSB], [http://www.ebi.ac.uk/pdbsum/6g7l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g7l ProSAT]</span></td></tr>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Halsa]]
	[[Category: Barty, A]]		[[Category: Barty, A]]
	[[Category: Bath, P]]		[[Category: Bath, P]]

OCA at 05:41, 27 June 2018

OCA — Wed, 27 Jun 2018 05:41:31 GMT

←Older revision		Revision as of 05:41, 27 June 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6g7l is ~~ON HOLD~~	+	==Retinal isomerization in bacteriorhodopsin revealed by a femtosecond X-ray laser: 8.3 ms state structure==
		+	<StructureSection load='6g7l' size='340' side='right' caption='[[6g7l]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6g7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum_(strain_atcc_700922_/_jcm_11081_/_nrc-1) Halobacterium salinarum (strain atcc 700922 / jcm 11081 / nrc-1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G7L FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g7l OCA], [http://pdbe.org/6g7l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g7l RCSB], [http://www.ebi.ac.uk/pdbsum/6g7l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g7l ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ultrafast isomerization of retinal is the primary step in photoresponsive biological functions including vision in humans and ion-transport across bacterial membranes. We studied the sub-picosecond structural dynamics of retinal isomerization in the light-driven proton pump bacteriorhodopsin using an x-ray laser. A series of structural snapshots with near-atomic spatial and temporal resolution in the femtosecond regime show how the excited all-trans retinal samples conformational states within the protein binding pocket prior to passing through a twisted geometry and emerging in the 13-cis conformation. Our findings suggest ultrafast collective motions of aspartic acid residues and functional water molecules in the proximity of the retinal Schiff base as a key ingredient for this stereo-selective and efficient photochemical reaction.

-	~~Authors:~~ Nogly, P., Weinert, T., James, D~~., Cabajo~~, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D~~., Bruenle~~, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.	+	Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser.,Nogly P, Weinert T, James D, Carbajo S, Ozerov D, Furrer A, Gashi D, Borin V, Skopintsev P, Jaeger K, Nass K, Bath P, Bosman R, Koglin J, Seaberg M, Lane T, Kekilli D, Brunle S, Tanaka T, Wu W, Milne C, White T, Barty A, Weierstall U, Panneels V, Nango E, Iwata S, Hunter M, Schapiro I, Schertler G, Neutze R, Standfuss J Science. 2018 Jun 14. pii: science.aat0094. doi: 10.1126/science.aat0094. PMID:29903883<ref>PMID:29903883</ref>

-	~~Description: Retinal isomerization in bacteriorhodopsin revealed by~~ a ~~femtosecond X-ray laser: 8~~.~~3 ms state structure~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Skopintsev, P]]~~	+	<div class="pdbe-citations 6g7l" style="background-color:#fffaf0;"></div>
-	~~[[Category: Nogly, P]]~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Barty, A]]		[[Category: Barty, A]]
-	[[Category: Wu, ~~W]]~~	+	[[Category: Bath, P]]
-	~~[[Category: Milne, C]]~~	+
-	~~[[Category: Schertler, G]]~~	+
-	~~[[Category: White, T~~]]	+
	[[Category: Borin, V]]		[[Category: Borin, V]]
-	[[Category: ~~Nango~~, E]]	+	[[Category: Bosman, R]]
		+	[[Category: Bruenle, S]]
		+	[[Category: Cabajo, S]]
	[[Category: Furrer, A]]		[[Category: Furrer, A]]
		+	[[Category: Gashi, D]]
	[[Category: Hunter, M]]		[[Category: Hunter, M]]
-	[[Category: ~~Seaberg, M]]~~	+	[[Category: Iwata, S]]
-	~~[[Category: Cabajo~~, S]]	+	[[Category: Jaeger, K]]
-	[[Category: ~~Ozerov, D]]~~	+
-	~~[[Category: Lane, T]]~~	+
-	~~[[Category: Nass~~, K]]	+
	[[Category: James, D]]		[[Category: James, D]]
-	[[Category: Weierstall, U]]
-	[[Category: Tanaka, T]]
-	[[Category: Bosman, R]]
-	[[Category: Schapiro, I]]
	[[Category: Kekilli, D]]		[[Category: Kekilli, D]]
-	[[Category: ~~Weinert~~, T]]	+	[[Category: Koglin, J]]
		+	[[Category: Lane, T]]
		+	[[Category: Milne, C]]
		+	[[Category: Nango, E]]
		+	[[Category: Nass, K]]
	[[Category: Neutze, R]]		[[Category: Neutze, R]]
-	[[Category: ~~Jaeger, K]]~~	+	[[Category: Nogly, P]]
-	~~[[Category: Bath~~, P]]	+	[[Category: Ozerov, D]]
-	[[Category: ~~Standfuss, J]]~~	+
-	~~[[Category: Iwata, S]]~~	+
-	~~[[Category: Bruenle~~, S]]	+
	[[Category: Panneels, V]]		[[Category: Panneels, V]]
-	[[Category: ~~Koglin~~, J]]	+	[[Category: Schapiro, I]]
-	[[Category: ~~Gashi~~, D]]	+	[[Category: Schertler, G]]
		+	[[Category: Seaberg, M]]
		+	[[Category: Skopintsev, P]]
		+	[[Category: Standfuss, J]]
		+	[[Category: Tanaka, T]]
		+	[[Category: Weierstall, U]]
		+	[[Category: Weinert, T]]
		+	[[Category: White, T]]
		+	[[Category: Wu, W]]
		+	[[Category: Femtosecond]]
		+	[[Category: Proton transport]]
		+	[[Category: Retinal isomerization]]
		+	[[Category: Room temperature]]
		+	[[Category: Time resolved crystallography]]
		+	[[Category: Ultrafast]]

OCA: Protected "6g7l" [edit=sysop:move=sysop]

OCA — Wed, 11 Apr 2018 12:43:48 GMT

Protected "6g7l" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:43, 11 April 2018

OCA: New page: '''Unreleased structure''' The entry 6g7l is ON HOLD Authors: Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Na...

OCA — Wed, 11 Apr 2018 12:43:47 GMT

New page: '''Unreleased structure''' The entry 6g7l is ON HOLD Authors: Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Na...

New page

'''Unreleased structure'''

The entry 6g7l is ON HOLD

Authors: Nogly, P., Weinert, T., James, D., Cabajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Bath, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Bruenle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., Standfuss, J.

Description: Retinal isomerization in bacteriorhodopsin revealed by a femtosecond X-ray laser: 8.3 ms state structure
[[Category: Unreleased Structures]]
[[Category: Skopintsev, P]]
[[Category: Nogly, P]]
[[Category: Barty, A]]
[[Category: Wu, W]]
[[Category: Milne, C]]
[[Category: Schertler, G]]
[[Category: White, T]]
[[Category: Borin, V]]
[[Category: Nango, E]]
[[Category: Furrer, A]]
[[Category: Hunter, M]]
[[Category: Seaberg, M]]
[[Category: Cabajo, S]]
[[Category: Ozerov, D]]
[[Category: Lane, T]]
[[Category: Nass, K]]
[[Category: James, D]]
[[Category: Weierstall, U]]
[[Category: Tanaka, T]]
[[Category: Bosman, R]]
[[Category: Schapiro, I]]
[[Category: Kekilli, D]]
[[Category: Weinert, T]]
[[Category: Neutze, R]]
[[Category: Jaeger, K]]
[[Category: Bath, P]]
[[Category: Standfuss, J]]
[[Category: Iwata, S]]
[[Category: Bruenle, S]]
[[Category: Panneels, V]]
[[Category: Koglin, J]]
[[Category: Gashi, D]]