6gc9 - Revision history

OCA at 08:53, 3 October 2018

OCA — Wed, 03 Oct 2018 08:53:17 GMT

←Older revision		Revision as of 08:53, 3 October 2018
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	<StructureSection load='6gc9' size='340' side='right' caption='[[6gc9]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='6gc9' size='340' side='right' caption='[[6gc9]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6gc9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GC9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6gc9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bjerkandera_versicolor Bjerkandera versicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GC9 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gc9 OCA], [http://pdbe.org/6gc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gc9 RCSB], [http://www.ebi.ac.uk/pdbsum/6gc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gc9 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gc9 OCA], [http://pdbe.org/6gc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gc9 RCSB], [http://www.ebi.ac.uk/pdbsum/6gc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gc9 ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bjerkandera versicolor]]
	[[Category: Didierjean, C]]		[[Category: Didierjean, C]]
	[[Category: Favier, F]]		[[Category: Favier, F]]

OCA at 07:33, 29 August 2018

OCA — Wed, 29 Aug 2018 07:33:02 GMT

←Older revision		Revision as of 07:33, 29 August 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6gc9 is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of glutathione transferase Xi 1 from Trametes versicolor==
		+	<StructureSection load='6gc9' size='340' side='right' caption='[[6gc9]], [[Resolution\|resolution]] 3.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6gc9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GC9 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gc9 OCA], [http://pdbe.org/6gc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gc9 RCSB], [http://www.ebi.ac.uk/pdbsum/6gc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gc9 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glutathione transferases (GSTs) from the Xi and Omega classes have a catalytic cysteine residue, which gives them reductase activities. Until now, they have been assigned distinct substrates. While Xi GSTs specifically reduce glutathionyl-(hydro)quinones, Omega GSTs are specialized in the reduction of glutathionyl-acetophenones. Here, we present the biochemical and structural analysis of TvGSTX1 and TvGSTX3 isoforms from the wood-degrading fungus Trametes versicolor. TvGSTX1 reduces GS-menadione as expected, while TvGSTX3 reduces both Xi and Omega substrates. An in-depth structural analysis indicates a broader active site for TvGSTX3 due to specific differences in the nature of the residues situated in the C-terminal helix alpha9. This feature could explain the catalytic duality of TvGSTX3. Based on phylogenetic analysis, we propose that this duality might exist in saprophytic fungi and ascomycetes. This article is protected by copyright. All rights reserved.

-	~~Authors:~~ Schwartz, M., ~~Favier~~, F., Didierjean, C.	+	Trametes versicolor Glutathione Transferase Xi 3, a dual Cys-GST with catalytic specificities of both Xi and Omega classes.,Schwartz M, Perrot T, Deroy A, Roret T, Morel-Rouhier M, Mulliert G, Gelhaye E, Favier F, Didierjean C FEBS Lett. 2018 Aug 15. doi: 10.1002/1873-3468.13224. PMID:30112765<ref>PMID:30112765</ref>

-	~~Description: Crystal structure~~ of ~~glutathione transferase Xi 1 from Trametes versicolor~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Schwartz, M]]~~	+	<div class="pdbe-citations 6gc9" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Didierjean, C]]		[[Category: Didierjean, C]]
	[[Category: Favier, F]]		[[Category: Favier, F]]
		+	[[Category: Schwartz, M]]
		+	[[Category: Glutathione transferase]]
		+	[[Category: Transferase]]

OCA at 06:52, 2 May 2018

OCA — Wed, 02 May 2018 06:52:09 GMT

←Older revision		Revision as of 06:52, 2 May 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6gc9 is ON HOLD	+	The entry 6gc9 is ON HOLD until Paper Publication

	Authors: Schwartz, M., Favier, F., Didierjean, C.		Authors: Schwartz, M., Favier, F., Didierjean, C.

OCA: Protected "6gc9" [edit=sysop:move=sysop]

OCA — Wed, 25 Apr 2018 04:21:41 GMT

Protected "6gc9" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:21, 25 April 2018

OCA: New page: '''Unreleased structure''' The entry 6gc9 is ON HOLD Authors: Schwartz, M., Favier, F., Didierjean, C. Description: Crystal structure of glutathione transferase Xi 1 from Trametes vers...

OCA — Wed, 25 Apr 2018 04:21:40 GMT

New page: '''Unreleased structure''' The entry 6gc9 is ON HOLD Authors: Schwartz, M., Favier, F., Didierjean, C. Description: Crystal structure of glutathione transferase Xi 1 from Trametes vers...

New page

'''Unreleased structure'''

The entry 6gc9 is ON HOLD

Authors: Schwartz, M., Favier, F., Didierjean, C.

Description: Crystal structure of glutathione transferase Xi 1 from Trametes versicolor
[[Category: Unreleased Structures]]
[[Category: Schwartz, M]]
[[Category: Didierjean, C]]
[[Category: Favier, F]]