6glt - Revision history

OCA at 06:43, 21 February 2019

OCA — Thu, 21 Feb 2019 06:43:14 GMT

←Older revision		Revision as of 06:43, 21 February 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6glt is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of hMTH1 D120N in the presence of acetate==
-		+	<StructureSection load='6glt' size='340' side='right' caption='[[6glt]], [[Resolution\|resolution]] 1.60Å' scene=''>
-	~~Authors~~: ~~Eberle~~, S.A., ~~Wiedmer~~, L.~~, Sledz, P~~., ~~Caflisch~~, A.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6glt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GLT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GLT FirstGlance]. <br>
-	~~Description: Crystal structure of hMTH1 D120N in the presence of acetate~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6glt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6glt OCA], [http://pdbe.org/6glt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6glt RCSB], [http://www.ebi.ac.uk/pdbsum/6glt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6glt ProSAT]</span></td></tr>
-	~~[[Category: Eberle~~, S.A]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/8ODP_HUMAN 8ODP_HUMAN]] Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP.<ref>PMID:10373420</ref> <ref>PMID:10608900</ref> <ref>PMID:11139615</ref> <ref>PMID:12857738</ref> <ref>PMID:22556419</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Caflisch, A]]		[[Category: Caflisch, A]]
		+	[[Category: Eberle, S A]]
	[[Category: Sledz, P]]		[[Category: Sledz, P]]
	[[Category: Wiedmer, L]]		[[Category: Wiedmer, L]]
		+	[[Category: Dna repair]]
		+	[[Category: Hydrolase]]

OCA at 04:28, 6 June 2018

OCA — Wed, 06 Jun 2018 04:28:28 GMT

←Older revision		Revision as of 04:28, 6 June 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6glt is ON HOLD	+	The entry 6glt is ON HOLD until Paper Publication

	Authors: Eberle, S.A., Wiedmer, L., Sledz, P., Caflisch, A.		Authors: Eberle, S.A., Wiedmer, L., Sledz, P., Caflisch, A.

-	Description: hMTH1 D120N	+	Description: Crystal structure of hMTH1 D120N in the presence of acetate
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Eberle, S.A]]
	[[Category: Caflisch, A]]		[[Category: Caflisch, A]]
-	[[Category: Wiedmer, L]]
	[[Category: Sledz, P]]		[[Category: Sledz, P]]
-	[[Category: ~~Eberle~~, ~~S.A~~]]	+	[[Category: Wiedmer, L]]

OCA: Protected "6glt" [edit=sysop:move=sysop]

OCA — Wed, 30 May 2018 04:21:38 GMT

Protected "6glt" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:21, 30 May 2018

OCA: New page: '''Unreleased structure''' The entry 6glt is ON HOLD Authors: Eberle, S.A., Wiedmer, L., Sledz, P., Caflisch, A. Description: hMTH1 D120N Category: Unreleased Structures [[Category...

OCA — Wed, 30 May 2018 04:21:37 GMT

New page: '''Unreleased structure''' The entry 6glt is ON HOLD Authors: Eberle, S.A., Wiedmer, L., Sledz, P., Caflisch, A. Description: hMTH1 D120N Category: Unreleased Structures [[Category...

New page

'''Unreleased structure'''

The entry 6glt is ON HOLD

Authors: Eberle, S.A., Wiedmer, L., Sledz, P., Caflisch, A.

Description: hMTH1 D120N
[[Category: Unreleased Structures]]
[[Category: Caflisch, A]]
[[Category: Wiedmer, L]]
[[Category: Sledz, P]]
[[Category: Eberle, S.A]]