6gmc - Revision history

OCA at 06:02, 27 June 2018

OCA — Wed, 27 Jun 2018 06:02:28 GMT

←Older revision		Revision as of 06:02, 27 June 2018
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	<StructureSection load='6gmc' size='340' side='right' caption='[[6gmc]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='6gmc' size='340' side='right' caption='[[6gmc]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6gmc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GMC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6gmc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GMC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C7C:5-[(4-CHLOROPHENYL)SULFANYL]-1,2,3-THIADIAZOLE-4-CARBOXYLATE'>C7C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C7C:5-[(4-CHLOROPHENYL)SULFANYL]-1,2,3-THIADIAZOLE-4-CARBOXYLATE'>C7C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nzl\|2nzl]], [[6gmb\|6gmb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nzl\|2nzl]], [[6gmb\|6gmb]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HAO1, GOX1, HAOX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmc OCA], [http://pdbe.org/6gmc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gmc RCSB], [http://www.ebi.ac.uk/pdbsum/6gmc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmc OCA], [http://pdbe.org/6gmc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gmc RCSB], [http://www.ebi.ac.uk/pdbsum/6gmc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmc ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bezerra, G A]]		[[Category: Bezerra, G A]]

OCA at 07:46, 14 June 2018

OCA — Thu, 14 Jun 2018 07:46:27 GMT

←Older revision		Revision as of 07:46, 14 June 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6gmc ~~is ON HOLD~~	+	==1.2 A resolution structure of human hydroxyacid oxidase 1 bound with FMN and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole==
-		+	<StructureSection load='6gmc' size='340' side='right' caption='[[6gmc]], [[Resolution\|resolution]] 1.20Å' scene=''>
-	~~Authors~~: ~~MacKinnon, S~~.~~, Bezerra, G~~.A., ~~Krojer~~, T., ~~Smee~~, C., ~~Arrowsmith~~, C.H., ~~Edwards~~, E., ~~Bountra, C~~., ~~Oppermann, U~~., ~~Brennan, P~~.E., ~~Yue, W~~.W.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6gmc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GMC FirstGlance]. <br>
-	~~Description~~: 1.2 ~~A resolution structure of human~~ hydroxyacid oxidase ~~1 bound with FMN and 4~~-~~carboxy-5-[(4~~-~~chlorophenyl)sulfanyl]-1~~,2,3-~~thiadiazole~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C7C:5-[(4-CHLOROPHENYL)SULFANYL]-1,2,3-THIADIAZOLE-4-CARBOXYLATE'>C7C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nzl\|2nzl]], [[6gmb\|6gmb]]</td></tr>
-	[[Category: ~~Smee~~, C]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr>
-	[[Category: ~~Yue~~, ~~W.W~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmc OCA], [http://pdbe.org/6gmc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gmc RCSB], [http://www.ebi.ac.uk/pdbsum/6gmc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmc ProSAT]</span></td></tr>
-	[[Category: ~~Mackinnon~~, S]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN]] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Arrowsmith, C H]]
		+	[[Category: Bezerra, G A]]
		+	[[Category: Bountra, C]]
		+	[[Category: Brennan, P E]]
		+	[[Category: Edwards, E]]
	[[Category: Krojer, T]]		[[Category: Krojer, T]]
-	[[Category: ~~Bountra~~, ~~C]]~~	+	[[Category: MacKinnon, S]]
-	~~[[Category: Arrowsmith, C.H~~]]	+
	[[Category: Oppermann, U]]		[[Category: Oppermann, U]]
-	[[Category: ~~Bezerra~~, ~~G.A~~]]	+	[[Category: Smee, C]]
-	[[Category: ~~Edwards~~, E]]	+	[[Category: Yue, W W]]
-	[[Category: ~~Brennan, P.E~~]]	+	[[Category: Fmn]]
		+	[[Category: Glycolate]]
		+	[[Category: Glyoxylate]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Peroxisome]]
		+	[[Category: Primary hyperoxaluria]]

OCA: Protected "6gmc" [edit=sysop:move=sysop]

OCA — Wed, 30 May 2018 04:22:43 GMT

Protected "6gmc" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:22, 30 May 2018

OCA: New page: '''Unreleased structure''' The entry 6gmc is ON HOLD Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Smee, C., Arrowsmith, C.H., Edwards, E., Bountra, C., Oppermann, U., Brennan, P.E...

OCA — Wed, 30 May 2018 04:22:42 GMT

New page: '''Unreleased structure''' The entry 6gmc is ON HOLD Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Smee, C., Arrowsmith, C.H., Edwards, E., Bountra, C., Oppermann, U., Brennan, P.E...

New page

'''Unreleased structure'''

The entry 6gmc is ON HOLD

Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Smee, C., Arrowsmith, C.H., Edwards, E., Bountra, C., Oppermann, U., Brennan, P.E., Yue, W.W.

Description: 1.2 A resolution structure of human hydroxyacid oxidase 1 bound with FMN and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole
[[Category: Unreleased Structures]]
[[Category: Smee, C]]
[[Category: Yue, W.W]]
[[Category: Mackinnon, S]]
[[Category: Krojer, T]]
[[Category: Bountra, C]]
[[Category: Arrowsmith, C.H]]
[[Category: Oppermann, U]]
[[Category: Bezerra, G.A]]
[[Category: Edwards, E]]
[[Category: Brennan, P.E]]