6gw7 - Revision history

OCA at 10:49, 14 June 2023

OCA — Wed, 14 Jun 2023 10:49:26 GMT

←Older revision		Revision as of 10:49, 14 June 2023
Line 1:		Line 1:

	==The CTD of HpDprA, a DNA binding Winged Helix domain which do not bind dsDNA==		==The CTD of HpDprA, a DNA binding Winged Helix domain which do not bind dsDNA==
-	<StructureSection load='6gw7' size='340' side='right'caption='[[6gw7~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='6gw7' size='340' side='right'caption='[[6gw7]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6gw7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_43504 Atcc 43504~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GW7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6GW7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6gw7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GW7 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB415_01075 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 ATCC 43504])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gw7 OCA], [https://pdbe.org/6gw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gw7 RCSB], [https://www.ebi.ac.uk/pdbsum/6gw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gw7 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6gw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gw7 OCA], [~~http~~://pdbe.org/6gw7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6gw7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6gw7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6gw7 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A2A6XLY0_HELPX A0A2A6XLY0_HELPX]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 43504]]
-	[[Category: Large Structures]]
-	[[Category: Andreani, J]]
-	[[Category: Celma, L]]
-	[[Category: Cuniasse, P]]
-	[[Category: Durand, D]]
-	[[Category: Guerois, R]]
-	[[Category: Lisboa, J]]
-	[[Category: Marquis, M]]
-	[[Category: Marsin, S]]
-	[[Category: Ochsenbein, F]]
-	[[Category: Quevillon-Cheruel, S]]
-	[[Category: Radicella, J P]]
-	[[Category: Sanchez, D]]
-	[[Category: Dna binding protein]]
-	[[Category: Dpra]]
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
-	[[Category: ~~Winged helix~~]]	+	[[Category: Large Structures]]
		+	[[Category: Andreani J]]
		+	[[Category: Celma L]]
		+	[[Category: Cuniasse P]]
		+	[[Category: Durand D]]
		+	[[Category: Guerois R]]
		+	[[Category: Lisboa J]]
		+	[[Category: Marquis M]]
		+	[[Category: Marsin S]]
		+	[[Category: Ochsenbein F]]
		+	[[Category: Quevillon-Cheruel S]]
		+	[[Category: Radicella JP]]
		+	[[Category: Sanchez D]]

OCA at 09:45, 18 November 2020

OCA — Wed, 18 Nov 2020 09:45:54 GMT

←Older revision		Revision as of 09:45, 18 November 2020
Line 3:		Line 3:
	<StructureSection load='6gw7' size='340' side='right'caption='[[6gw7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='6gw7' size='340' side='right'caption='[[6gw7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6gw7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GW7 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6GW7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6gw7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GW7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6GW7 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB415_01075 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 ATCC 43504])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB415_01075 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 ATCC 43504])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6gw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gw7 OCA], [http://pdbe.org/6gw7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gw7 RCSB], [http://www.ebi.ac.uk/pdbsum/6gw7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gw7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6gw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gw7 OCA], [http://pdbe.org/6gw7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gw7 RCSB], [http://www.ebi.ac.uk/pdbsum/6gw7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gw7 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:33, 10 May 2019

OCA — Fri, 10 May 2019 13:33:16 GMT

←Older revision		Revision as of 13:33, 10 May 2019
Line 3:		Line 3:
	<StructureSection load='6gw7' size='340' side='right'caption='[[6gw7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='6gw7' size='340' side='right'caption='[[6gw7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6gw7]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GW7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GW7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6gw7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GW7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GW7 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gw7 OCA], [http://pdbe.org/6gw7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gw7 RCSB], [http://www.ebi.ac.uk/pdbsum/6gw7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gw7 ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB415_01075 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 ATCC 43504])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gw7 OCA], [http://pdbe.org/6gw7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gw7 RCSB], [http://www.ebi.ac.uk/pdbsum/6gw7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gw7 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 43504]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Andreani, J]]		[[Category: Andreani, J]]

OCA at 06:47, 24 April 2019

OCA — Wed, 24 Apr 2019 06:47:15 GMT

←Older revision		Revision as of 06:47, 24 April 2019
Line 1:		Line 1:
-	'''Unreleased structure'''

-	The ~~entry~~ 6gw7 is ~~ON HOLD~~	+	==The CTD of HpDprA, a DNA binding Winged Helix domain which do not bind dsDNA==
		+	<StructureSection load='6gw7' size='340' side='right'caption='[[6gw7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6gw7]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GW7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GW7 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gw7 OCA], [http://pdbe.org/6gw7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gw7 RCSB], [http://www.ebi.ac.uk/pdbsum/6gw7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gw7 ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	DprA, a ubiquitous multidomain DNA-binding protein, plays a crucial role during natural transformation in bacteria. Here, we carried out the structural analysis of DprA from the human pathogen Helicobacter pylori by combining data issued from the 1.8 A resolution X-ray structure of the Pfam02481 domain dimer (RF), the NMR structure of the carboxy-terminal domain (CTD) and the low-resolution structure of the full-length DprA dimer obtained in solution by SAXS. In particular, we sought a molecular function for the CTD, a domain that we show here is essential for transformation in H. pylori. Albeit its structural homology to winged helix DNA binding motifs, we confirmed that the isolated CTD does not interact with ssDNA nor with dsDNA. The key R52 and K137 residues of RF are crucial for these two interactions. Search for sequences harboring homology to either HpDprA or Rhodopseudomonas palustris DprA CTDs led to the identification of conserved patches in the two CTD. Our structural study revealed the similarity of the structures adopted by these residues in RpDprA CTD and HpDprA CTD. This argues for a conserved, but yet to be defined, CTD function, distinct from DNA binding. This article is protected by copyright. All rights reserved.

-	~~Authors: Lisboa~~, J., Celma, L., Sanchez, D., Marquis, M., Andreani, J., Guerois, R., Ochsenbein, F., Durand, D., Marsin, S., Cuniasse, P., Radicella~~, J.P.~~, Quevillon-Cheruel, S.	+	The C-terminal domain of HpDprA is a DNA-binding Winged Helix domain that does not bind double-stranded DNA.,Lisboa J, Celma L, Sanchez D, Marquis M, Andreani J, Guerois R, Ochsenbein F, Durand D, Marsin S, Cuniasse P, Radicella JP, Quevillon-Cheruel S FEBS J. 2019 Feb 16. doi: 10.1111/febs.14788. PMID:30771270<ref>PMID:30771270</ref>

-	~~Description: The CTD of HpDprA~~, a ~~DNA binding Winged Helix domain which do not bind dsDNA~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Durand, D]]~~	+	<div class="pdbe-citations 6gw7" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Radicella, J.P~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Andreani, J]]		[[Category: Andreani, J]]
		+	[[Category: Celma, L]]
		+	[[Category: Cuniasse, P]]
		+	[[Category: Durand, D]]
		+	[[Category: Guerois, R]]
		+	[[Category: Lisboa, J]]
	[[Category: Marquis, M]]		[[Category: Marquis, M]]
-	[[Category: Sanchez, D]]
	[[Category: Marsin, S]]		[[Category: Marsin, S]]
	[[Category: Ochsenbein, F]]		[[Category: Ochsenbein, F]]
-	[[Category: Cuniasse, P]]
-	[[Category: Guerois, R]]
	[[Category: Quevillon-Cheruel, S]]		[[Category: Quevillon-Cheruel, S]]
-	[[Category: ~~Celma~~, L]]	+	[[Category: Radicella, J P]]
-	[[Category: ~~Lisboa~~, J]]	+	[[Category: Sanchez, D]]
		+	[[Category: Dna binding protein]]
		+	[[Category: Dpra]]
		+	[[Category: Helicobacter pylori]]
		+	[[Category: Winged helix]]

OCA: Protected "6gw7" [edit=sysop:move=sysop]

OCA — Wed, 27 Jun 2018 04:20:33 GMT

Protected "6gw7" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:20, 27 June 2018

OCA: New page: '''Unreleased structure''' The entry 6gw7 is ON HOLD Authors: Lisboa, J., Celma, L., Sanchez, D., Marquis, M., Andreani, J., Guerois, R., Ochsenbein, F., Durand, D., Marsin, S., Cuniass...

OCA — Wed, 27 Jun 2018 04:20:31 GMT

New page: '''Unreleased structure''' The entry 6gw7 is ON HOLD Authors: Lisboa, J., Celma, L., Sanchez, D., Marquis, M., Andreani, J., Guerois, R., Ochsenbein, F., Durand, D., Marsin, S., Cuniass...

New page

'''Unreleased structure'''

The entry 6gw7 is ON HOLD

Authors: Lisboa, J., Celma, L., Sanchez, D., Marquis, M., Andreani, J., Guerois, R., Ochsenbein, F., Durand, D., Marsin, S., Cuniasse, P., Radicella, J.P., Quevillon-Cheruel, S.

Description: The CTD of HpDprA, a DNA binding Winged Helix domain which do not bind dsDNA
[[Category: Unreleased Structures]]
[[Category: Durand, D]]
[[Category: Radicella, J.P]]
[[Category: Andreani, J]]
[[Category: Marquis, M]]
[[Category: Sanchez, D]]
[[Category: Marsin, S]]
[[Category: Ochsenbein, F]]
[[Category: Cuniasse, P]]
[[Category: Guerois, R]]
[[Category: Quevillon-Cheruel, S]]
[[Category: Celma, L]]
[[Category: Lisboa, J]]