6gw9 - Revision history

OCA at 07:55, 12 September 2018

OCA — Wed, 12 Sep 2018 07:55:18 GMT

←Older revision		Revision as of 07:55, 12 September 2018
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	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/CONV_CANCT CONV_CANCT]] D-mannose/D-glucose-binding lectin which binds alpha-methyl-D-mannoside, D-mannose and D-glucose in that order (PubMed:24519628, PubMed:27737777). Also binds to serum fetuin and ovalbumin (PubMed:24519628). Has hemagglutinating activity towards rabbit erythrocytes (PubMed:24519628). Is not toxic towards larvae of the brine shrimp Artemia (PubMed:24519628). Induces relaxation in rat endothelized aorta (PubMed:24519628). Shows a transient edematogenic effect in rat (PubMed:27737777).<ref>PMID:24519628</ref> <ref>PMID:27737777</ref>		[[http://www.uniprot.org/uniprot/CONV_CANCT CONV_CANCT]] D-mannose/D-glucose-binding lectin which binds alpha-methyl-D-mannoside, D-mannose and D-glucose in that order (PubMed:24519628, PubMed:27737777). Also binds to serum fetuin and ovalbumin (PubMed:24519628). Has hemagglutinating activity towards rabbit erythrocytes (PubMed:24519628). Is not toxic towards larvae of the brine shrimp Artemia (PubMed:24519628). Induces relaxation in rat endothelized aorta (PubMed:24519628). Shows a transient edematogenic effect in rat (PubMed:27737777).<ref>PMID:24519628</ref> <ref>PMID:27737777</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	X-ray free-electron lasers (XFELs) enable novel experiments because of their high peak brilliance and femtosecond pulse duration. However, non-superconducting XFELs offer repetition rates of only 10-120 Hz, placing significant demands on beam time and sample consumption. We describe serial femtosecond crystallography experiments performed at the European XFEL, the first MHz repetition rate XFEL, delivering 1.128 MHz X-ray pulse trains at 10 Hz. Given the short spacing between pulses, damage caused by shock waves launched by one XFEL pulse on sample probed by subsequent pulses is a concern. To investigate this issue, we collected data from lysozyme microcrystals, exposed to a ~15 mum XFEL beam. Under these conditions, data quality is independent of whether the first or subsequent pulses of the train were used for data collection. We also analyzed a mixture of microcrystals of jack bean proteins, from which the structure of native, magnesium-containing concanavalin A was determined.
		+
		+	Megahertz data collection from protein microcrystals at an X-ray free-electron laser.,Grunbein ML, Bielecki J, Gorel A, Stricker M, Bean R, Cammarata M, Dorner K, Frohlich L, Hartmann E, Hauf S, Hilpert M, Kim Y, Kloos M, Letrun R, Messerschmidt M, Mills G, Nass Kovacs G, Ramilli M, Roome CM, Sato T, Scholz M, Sliwa M, Sztuk-Dambietz J, Weik M, Weinhausen B, Al-Qudami N, Boukhelef D, Brockhauser S, Ehsan W, Emons M, Esenov S, Fangohr H, Kaukher A, Kluyver T, Lederer M, Maia L, Manetti M, Michelat T, Munnich A, Pallas F, Palmer G, Previtali G, Raab N, Silenzi A, Szuba J, Venkatesan S, Wrona K, Zhu J, Doak RB, Shoeman RL, Foucar L, Colletier JP, Mancuso AP, Barends TRM, Stan CA, Schlichting I Nat Commun. 2018 Aug 28;9(1):3487. doi: 10.1038/s41467-018-05953-4. PMID:30154468<ref>PMID:30154468</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6gw9" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:13, 5 September 2018

OCA — Wed, 05 Sep 2018 10:13:38 GMT

←Older revision		Revision as of 10:13, 5 September 2018
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-	'''Unreleased structure'''

-	~~The entry~~ 6gw9 is ~~ON HOLD~~ ~~until Paper Publication~~	+	==Concanavalin A structure determined with data from the EuXFEL, the first MHz free electron laser==
-		+	<StructureSection load='6gw9' size='340' side='right' caption='[[6gw9]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6gw9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_cathartica Canavalia cathartica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GW9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GW9 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gw9 OCA], [http://pdbe.org/6gw9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gw9 RCSB], [http://www.ebi.ac.uk/pdbsum/6gw9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gw9 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CONV_CANCT CONV_CANCT]] D-mannose/D-glucose-binding lectin which binds alpha-methyl-D-mannoside, D-mannose and D-glucose in that order (PubMed:24519628, PubMed:27737777). Also binds to serum fetuin and ovalbumin (PubMed:24519628). Has hemagglutinating activity towards rabbit erythrocytes (PubMed:24519628). Is not toxic towards larvae of the brine shrimp Artemia (PubMed:24519628). Induces relaxation in rat endothelized aorta (PubMed:24519628). Shows a transient edematogenic effect in rat (PubMed:27737777).<ref>PMID:24519628</ref> <ref>PMID:27737777</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Canavalia cathartica]]
		+	[[Category: Barends, T R.M]]
		+	[[Category: Bean, R]]
		+	[[Category: Bielecki, J]]
		+	[[Category: Colletier, J P]]
		+	[[Category: Doak, R B]]
		+	[[Category: Doerner, K]]
		+	[[Category: Foucar, L]]
		+	[[Category: Gorel, A]]
		+	[[Category: Gruenbein, M L]]
		+	[[Category: Hartmann, E]]
		+	[[Category: Hilpert, M]]
		+	[[Category: Kloos, M]]
		+	[[Category: Letrun, R]]
		+	[[Category: Mancuso, A]]
		+	[[Category: Meserschmidt, M]]
		+	[[Category: Nass-Kovacs, G]]
		+	[[Category: Ramilli, M]]
		+	[[Category: Roome, C M]]
		+	[[Category: Sato, T]]
		+	[[Category: Schlichting, I]]
		+	[[Category: Shoeman, R L]]
		+	[[Category: Stan, C]]
		+	[[Category: Stricker, M]]
		+	[[Category: Sztuk-Dambietz, J]]
		+	[[Category: Free-electron laser]]
		+	[[Category: Lectin]]
		+	[[Category: Serial crystallography]]
		+	[[Category: Sugar binding protein]]

OCA at 17:10, 1 August 2018

OCA — Wed, 01 Aug 2018 17:10:58 GMT

←Older revision		Revision as of 17:10, 1 August 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6gw9 is ON HOLD	+	The entry 6gw9 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6gw9" [edit=sysop:move=sysop]

OCA — Wed, 04 Jul 2018 05:52:40 GMT

Protected "6gw9" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:52, 4 July 2018

OCA: New page: '''Unreleased structure''' The entry 6gw9 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 04 Jul 2018 05:52:38 GMT

New page: '''Unreleased structure''' The entry 6gw9 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6gw9 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]