6h1p - Revision history

OCA at 08:34, 24 July 2019

OCA — Wed, 24 Jul 2019 08:34:13 GMT

←Older revision		Revision as of 08:34, 24 July 2019
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	<StructureSection load='6h1p' size='340' side='right'caption='[[6h1p]], [[Resolution\|resolution]] 3.01Å' scene=''>		<StructureSection load='6h1p' size='340' side='right'caption='[[6h1p]], [[Resolution\|resolution]] 3.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6h1p]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H1P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6h1p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_sp._32cb Arthrobacter sp. 32cb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H1P FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6etz\|6etz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6etz\|6etz]]</td></tr>
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	</div>		</div>
	<div class="pdbe-citations 6h1p" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6h1p" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Galactosidase 3D structures\|Galactosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arthrobacter sp. 32cb]]
	[[Category: Beta-galactosidase]]		[[Category: Beta-galactosidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 06:47, 26 June 2019

OCA — Wed, 26 Jun 2019 06:47:08 GMT

←Older revision		Revision as of 06:47, 26 June 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6h1p is ~~ON HOLD until Paper~~ Publication	+	==Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB - data collected at room temperature==
		+	<StructureSection load='6h1p' size='340' side='right'caption='[[6h1p]], [[Resolution\|resolution]] 3.01Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6h1p]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H1P FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6etz\|6etz]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h1p OCA], [http://pdbe.org/6h1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h1p RCSB], [http://www.ebi.ac.uk/pdbsum/6h1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h1p ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Crystal structures of cold-adapted beta-D-galactosidase (EC 3.2.1.23) from the Antarctic bacterium Arthrobacter sp. 32cB (ArthbetaDG) have been determined in an unliganded form resulting from diffraction experiments conducted at 100K (at resolution 1.8A) and at room temperature (at resolution 3.0A). A detailed comparison of those two structures of the same enzyme was performed in order to estimate differences in their molecular flexibility and rigidity and to study structural rationalization for the cold-adaptation of the investigated enzyme. Furthermore, a comparative analysis with structures of homologous enzymes from psychrophilic, mesophilic, and thermophilic sources has been discussed to elucidate the relationship between structure and cold-adaptation in a wider context. The performed studies confirm that the structure of cold-adapted ArthbetaDG maintains balance between molecular stability and structural flexibility, which can be observed independently on the temperature of conducted X-ray diffraction experiments. Obtained information about proper protein function under given conditions provide a guideline for rational engineering of proteins in terms of their temperature optimum and thermal stability.

-	~~Authors: Rutkiewicz~~, M., Bujacz, A., Bujacz, G.	+	Structural features of cold-adapted dimeric GH2 beta-D-galactosidase from Arthrobacter sp. 32cB.,Rutkiewicz M, Bujacz A, Bujacz G Biochim Biophys Acta Proteins Proteom. 2019 Jun 10. pii: S1570-9639(19)30103-7., doi: 10.1016/j.bbapap.2019.06.001. PMID:31195142<ref>PMID:31195142</ref>

-	~~Description: Cold~~-~~adapted beta~~-~~D-galactosidase from Arthrobacter sp. 32cB -data collected at room temperature~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	[[Category: ~~Rutkiewicz, M~~]]	+	<div class="pdbe-citations 6h1p" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Bujacz, G~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-galactosidase]]
		+	[[Category: Large Structures]]
	[[Category: Bujacz, A]]		[[Category: Bujacz, A]]
		+	[[Category: Bujacz, G]]
		+	[[Category: Rutkiewicz, M]]
		+	[[Category: Cold-adapted]]
		+	[[Category: Dimer]]
		+	[[Category: Gh 2 family]]
		+	[[Category: Hydrolase]]
		+	[[Category: Psychrophilic]]

OCA at 06:01, 25 July 2018

OCA — Wed, 25 Jul 2018 06:01:54 GMT

←Older revision		Revision as of 06:01, 25 July 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6h1p is ON HOLD	+	The entry 6h1p is ON HOLD until Paper Publication

	Authors: Rutkiewicz, M., Bujacz, A., Bujacz, G.		Authors: Rutkiewicz, M., Bujacz, A., Bujacz, G.

OCA: Protected "6h1p" [edit=sysop:move=sysop]

OCA — Wed, 18 Jul 2018 05:55:28 GMT

Protected "6h1p" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:55, 18 July 2018

OCA: New page: '''Unreleased structure''' The entry 6h1p is ON HOLD Authors: Rutkiewicz, M., Bujacz, A., Bujacz, G. Description: Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB -data col...

OCA — Wed, 18 Jul 2018 05:55:27 GMT

New page: '''Unreleased structure''' The entry 6h1p is ON HOLD Authors: Rutkiewicz, M., Bujacz, A., Bujacz, G. Description: Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB -data col...

New page

'''Unreleased structure'''

The entry 6h1p is ON HOLD

Authors: Rutkiewicz, M., Bujacz, A., Bujacz, G.

Description: Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB -data collected at room temperature
[[Category: Unreleased Structures]]
[[Category: Rutkiewicz, M]]
[[Category: Bujacz, G]]
[[Category: Bujacz, A]]