6h2b - Revision history

OCA at 01:12, 11 April 2020

OCA — Sat, 11 Apr 2020 01:12:17 GMT

←Older revision		Revision as of 01:12, 11 April 2020
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	<SX load='6h2b' size='340' side='right' viewer='molstar' caption='[[6h2b]], [[Resolution\|resolution]] 3.28Å' scene=''>		<SX load='6h2b' size='340' side='right' viewer='molstar' caption='[[6h2b]], [[Resolution\|resolution]] 3.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6h2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mrnv Mrnv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2B OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6H2B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6h2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mrnv Mrnv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2B OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6H2B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=222557 MRNV])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=222557 MRNV])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h2b OCA], [http://pdbe.org/6h2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h2b RCSB], [http://www.ebi.ac.uk/pdbsum/6h2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h2b ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h2b OCA], [http://pdbe.org/6h2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h2b RCSB], [http://www.ebi.ac.uk/pdbsum/6h2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h2b ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 21:36, 6 March 2020

OCA — Fri, 06 Mar 2020 21:36:08 GMT

←Older revision		Revision as of 21:36, 6 March 2020
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	==Structure of the Macrobrachium rosenbergii Nodavirus==		==Structure of the Macrobrachium rosenbergii Nodavirus==
-	<~~StructureSection~~ load='6h2b' size='340' side='right'caption='[[6h2b]], [[Resolution\|resolution]] 3.28Å' scene=''>	+	<SX load='6h2b' size='340' side='right' viewer='molstar' caption='[[6h2b]], [[Resolution\|resolution]] 3.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6h2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mrnv Mrnv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H2B FirstGlance]. <br>		<table><tr><td colspan='2'>[[6h2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mrnv Mrnv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H2B FirstGlance]. <br>
Line 20:		Line 20:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Mrnv]]		[[Category: Mrnv]]

OCA at 10:39, 18 December 2019

OCA — Wed, 18 Dec 2019 10:39:19 GMT

←Older revision		Revision as of 10:39, 18 December 2019
Line 1:		Line 1:

	==Structure of the Macrobrachium rosenbergii Nodavirus==		==Structure of the Macrobrachium rosenbergii Nodavirus==
-	<StructureSection load='6h2b' size='340' side='right' caption='[[6h2b]], [[Resolution\|resolution]] 3.28Å' scene=''>	+	<StructureSection load='6h2b' size='340' side='right'caption='[[6h2b]], [[Resolution\|resolution]] 3.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6h2b]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H2B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6h2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mrnv Mrnv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H2B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=222557 MRNV])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h2b OCA], [http://pdbe.org/6h2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h2b RCSB], [http://www.ebi.ac.uk/pdbsum/6h2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h2b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h2b OCA], [http://pdbe.org/6h2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h2b RCSB], [http://www.ebi.ac.uk/pdbsum/6h2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h2b ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Mrnv]]
	[[Category: Beh, P L]]		[[Category: Beh, P L]]
	[[Category: Bhella, D]]		[[Category: Bhella, D]]

OCA at 06:57, 31 October 2018

OCA — Wed, 31 Oct 2018 06:57:45 GMT

←Older revision		Revision as of 06:57, 31 October 2018
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 6h2b is ~~ON HOLD until Paper~~ Publication	+	==Structure of the Macrobrachium rosenbergii Nodavirus==
		+	<StructureSection load='6h2b' size='340' side='right' caption='[[6h2b]], [[Resolution\|resolution]] 3.28Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[6h2b]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H2B FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h2b OCA], [http://pdbe.org/6h2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h2b RCSB], [http://www.ebi.ac.uk/pdbsum/6h2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h2b ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Macrobrachium rosenbergii nodavirus (MrNV) is a pathogen of freshwater prawns that poses a threat to food security and causes significant economic losses in the aquaculture industries of many developing nations. A detailed understanding of the MrNV virion structure will inform the development of strategies to control outbreaks. The MrNV capsid has also been engineered to display heterologous antigens, and thus knowledge of its atomic resolution structure will benefit efforts to develop tools based on this platform. Here, we present an atomic-resolution model of the MrNV capsid protein (CP), calculated by cryogenic electron microscopy (cryoEM) of MrNV virus-like particles (VLPs) produced in insect cells, and three-dimensional (3D) image reconstruction at 3.3 A resolution. CryoEM of MrNV virions purified from infected freshwater prawn post-larvae yielded a 6.6 A resolution structure, confirming the biological relevance of the VLP structure. Our data revealed that unlike other known nodavirus structures, which have been shown to assemble capsids having trimeric spikes, MrNV assembles a T = 3 capsid with dimeric spikes. We also found a number of surprising similarities between the MrNV capsid structure and that of the Tombusviridae: 1) an extensive network of N-terminal arms (NTAs) lines the capsid interior, forming long-range interactions to lace together asymmetric units; 2) the capsid shell is stabilised by 3 pairs of Ca2+ ions in each asymmetric unit; 3) the protruding spike domain exhibits a very similar fold to that seen in the spikes of the tombusviruses. These structural similarities raise questions concerning the taxonomic classification of MrNV.

-	~~Authors~~: Ho~~, K.H.~~, Gabrielsen, M., Beh~~, P.L.~~, Kueh~~, C.L.~~, Thong~~, Q.X.~~, Streetley, J., Tan~~, W.S.~~, Bhella, D.	+	Structure of the Macrobrachium rosenbergii nodavirus: A new genus within the Nodaviridae?,Ho KL, Gabrielsen M, Beh PL, Kueh CL, Thong QX, Streetley J, Tan WS, Bhella D PLoS Biol. 2018 Oct 22;16(10):e3000038. doi: 10.1371/journal.pbio.3000038. PMID:30346944<ref>PMID:30346944</ref>

-	~~Description: Structure~~ of the ~~Macrobrachium rosenbergii Nodavirus~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Tan, W.S]]~~	+	<div class="pdbe-citations 6h2b" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Kueh~~, C.L]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beh, P L]]
	[[Category: Bhella, D]]		[[Category: Bhella, D]]
-	[[Category: Streetley, J]]
-	[[Category: Thong, Q.X]]
	[[Category: Gabrielsen, M]]		[[Category: Gabrielsen, M]]
-	[[Category: ~~Beh~~, P.L]]	+	[[Category: Ho, K H]]
-	[[Category: Ho, ~~K.H~~]]	+	[[Category: Kueh, C L]]
		+	[[Category: Streetley, J]]
		+	[[Category: Tan, W S]]
		+	[[Category: Thong, Q X]]
		+	[[Category: Capsid]]
		+	[[Category: Nodavirus]]
		+	[[Category: Virion]]
		+	[[Category: Virus like particle]]

OCA at 04:08, 24 October 2018

OCA — Wed, 24 Oct 2018 04:08:22 GMT

←Older revision		Revision as of 04:08, 24 October 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6h2b is ON HOLD	+	The entry 6h2b is ON HOLD until Paper Publication

	Authors: Ho, K.H., Gabrielsen, M., Beh, P.L., Kueh, C.L., Thong, Q.X., Streetley, J., Tan, W.S., Bhella, D.		Authors: Ho, K.H., Gabrielsen, M., Beh, P.L., Kueh, C.L., Thong, Q.X., Streetley, J., Tan, W.S., Bhella, D.
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	[[Category: Kueh, C.L]]		[[Category: Kueh, C.L]]
	[[Category: Bhella, D]]		[[Category: Bhella, D]]
		+	[[Category: Streetley, J]]
	[[Category: Thong, Q.X]]		[[Category: Thong, Q.X]]
	[[Category: Gabrielsen, M]]		[[Category: Gabrielsen, M]]
	[[Category: Beh, P.L]]		[[Category: Beh, P.L]]
-	[[Category: Streetley, J]]
	[[Category: Ho, K.H]]		[[Category: Ho, K.H]]

OCA at 20:02, 9 August 2018

OCA — Thu, 09 Aug 2018 20:02:24 GMT

←Older revision		Revision as of 20:02, 9 August 2018
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6h2b is ON HOLD ~~until sometime in the future~~	+	The entry 6h2b is ON HOLD

	Authors: Ho, K.H., Gabrielsen, M., Beh, P.L., Kueh, C.L., Thong, Q.X., Streetley, J., Tan, W.S., Bhella, D.		Authors: Ho, K.H., Gabrielsen, M., Beh, P.L., Kueh, C.L., Thong, Q.X., Streetley, J., Tan, W.S., Bhella, D.

OCA: Protected "6h2b" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2018 06:02:10 GMT

Protected "6h2b" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:02, 25 July 2018

OCA: New page: '''Unreleased structure''' The entry 6h2b is ON HOLD until sometime in the future Authors: Ho, K.H., Gabrielsen, M., Beh, P.L., Kueh, C.L., Thong, Q.X., Streetley, J., Tan, W.S., Bhella...

OCA — Wed, 25 Jul 2018 06:02:09 GMT

New page: '''Unreleased structure''' The entry 6h2b is ON HOLD until sometime in the future Authors: Ho, K.H., Gabrielsen, M., Beh, P.L., Kueh, C.L., Thong, Q.X., Streetley, J., Tan, W.S., Bhella...

New page

'''Unreleased structure'''

The entry 6h2b is ON HOLD until sometime in the future

Authors: Ho, K.H., Gabrielsen, M., Beh, P.L., Kueh, C.L., Thong, Q.X., Streetley, J., Tan, W.S., Bhella, D.

Description: Structure of the Macrobrachium rosenbergii Nodavirus
[[Category: Unreleased Structures]]
[[Category: Tan, W.S]]
[[Category: Kueh, C.L]]
[[Category: Bhella, D]]
[[Category: Thong, Q.X]]
[[Category: Gabrielsen, M]]
[[Category: Beh, P.L]]
[[Category: Streetley, J]]
[[Category: Ho, K.H]]