6h3p - Revision history

OCA at 09:30, 30 January 2019

OCA — Wed, 30 Jan 2019 09:30:21 GMT

←Older revision		Revision as of 09:30, 30 January 2019
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	<StructureSection load='6h3p' size='340' side='right' caption='[[6h3p]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='6h3p' size='340' side='right' caption='[[6h3p]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[6h3p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H3P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H3P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[6h3p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Maize Maize]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H3P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H3P FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h3p OCA], [http://pdbe.org/6h3p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h3p RCSB], [http://www.ebi.ac.uk/pdbsum/6h3p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h3p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h3p OCA], [http://pdbe.org/6h3p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h3p RCSB], [http://www.ebi.ac.uk/pdbsum/6h3p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h3p ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fungi-induced plant diseases affect global food security and plant ecology. The biotrophic fungus Ustilago maydis causes smut disease in maize (Zea mays) plants by secreting numerous virulence effectors that reprogram plant metabolism and immune responses(1,2). The secreted fungal chorismate mutase Cmu1 presumably affects biosynthesis of the plant immune signal salicylic acid by channelling chorismate into the phenylpropanoid pathway(3). Here we show that one of the 20 maize-encoded kiwellins (ZmKWL1) specifically blocks the catalytic activity of Cmu1. ZmKWL1 hinders substrate access to the active site of Cmu1 through intimate interactions involving structural features that are specific to fungal Cmu1 orthologues. Phylogenetic analysis suggests that plant kiwellins have a versatile scaffold that can specifically counteract pathogen effectors such as Cmu1. We reveal the biological activity of a member of the kiwellin family, a widely conserved group of proteins that have previously been recognized only as important human allergens.
		+
		+	A kiwellin disarms the metabolic activity of a secreted fungal virulence factor.,Han X, Altegoer F, Steinchen W, Binnebesel L, Schuhmacher J, Glatter T, Giammarinaro PI, Djamei A, Rensing SA, Reissmann S, Kahmann R, Bange G Nature. 2019 Jan 16. pii: 10.1038/s41586-018-0857-9. doi:, 10.1038/s41586-018-0857-9. PMID:30651637<ref>PMID:30651637</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 6h3p" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
		+	[[Category: Maize]]
	[[Category: Altegoer, F]]		[[Category: Altegoer, F]]
	[[Category: Bange, G]]		[[Category: Bange, G]]
	[[Category: Plant protein]]		[[Category: Plant protein]]
	[[Category: Zea may]]		[[Category: Zea may]]

OCA at 12:09, 16 January 2019

OCA — Wed, 16 Jan 2019 12:09:12 GMT

←Older revision		Revision as of 12:09, 16 January 2019
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-	'''Unreleased structure'''

-	~~The entry~~ 6h3p is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of the cytoplasmic chorismate mutase from Zea mays==
-		+	<StructureSection load='6h3p' size='340' side='right' caption='[[6h3p]], [[Resolution\|resolution]] 2.70Å' scene=''>
-	~~Authors~~: ~~Altegoer~~, F., ~~Bange~~, G.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6h3p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H3P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H3P FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure of the cytoplasmic chorismate~~ mutase ~~from Zea mays~~	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h3p OCA], [http://pdbe.org/6h3p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h3p RCSB], [http://www.ebi.ac.uk/pdbsum/6h3p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h3p ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chorismate mutase]]
		+	[[Category: Altegoer, F]]
	[[Category: Bange, G]]		[[Category: Bange, G]]
-	[[Category: ~~Altegoer, F~~]]	+	[[Category: Plant protein]]
		+	[[Category: Zea may]]

OCA at 04:51, 22 August 2018

OCA — Wed, 22 Aug 2018 04:51:33 GMT

←Older revision		Revision as of 04:51, 22 August 2018
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 6h3p is ON HOLD	+	The entry 6h3p is ON HOLD until Paper Publication

	Authors: Altegoer, F., Bange, G.		Authors: Altegoer, F., Bange, G.

OCA: Protected "6h3p" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2018 06:06:21 GMT

Protected "6h3p" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:06, 25 July 2018

OCA: New page: '''Unreleased structure''' The entry 6h3p is ON HOLD Authors: Altegoer, F., Bange, G. Description: Crystal structure of the cytoplasmic chorismate mutase from Zea mays [[Category: Unre...

OCA — Wed, 25 Jul 2018 06:06:19 GMT

New page: '''Unreleased structure''' The entry 6h3p is ON HOLD Authors: Altegoer, F., Bange, G. Description: Crystal structure of the cytoplasmic chorismate mutase from Zea mays [[Category: Unre...

New page

'''Unreleased structure'''

The entry 6h3p is ON HOLD

Authors: Altegoer, F., Bange, G.

Description: Crystal structure of the cytoplasmic chorismate mutase from Zea mays
[[Category: Unreleased Structures]]
[[Category: Bange, G]]
[[Category: Altegoer, F]]