OCA at 09:37, 18 March 2020

OCA — Wed, 18 Mar 2020 09:37:39 GMT

←Older revision		Revision as of 09:37, 18 March 2020
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-	'''Unreleased structure'''

-	~~The entry~~ 6hjl ~~is ON HOLD~~	+	==Affimer:BclxL==
-		+	<StructureSection load='6hjl' size='340' side='right'caption='[[6hjl]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6hjl]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HJL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HJL FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hjl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hjl OCA], [http://pdbe.org/6hjl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hjl RCSB], [http://www.ebi.ac.uk/pdbsum/6hjl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hjl ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased~~ Structures]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/B2CL1_HUMAN B2CL1_HUMAN]] Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.<ref>PMID:19917720</ref> <ref>PMID:21840391</ref> Isoform Bcl-X(S) promotes apoptosis.<ref>PMID:19917720</ref> <ref>PMID:21840391</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Edwards, T A]]
		+	[[Category: Miles, J A]]
		+	[[Category: Tomlinson, D C]]
		+	[[Category: Trinh, C H]]
		+	[[Category: Wilson, A J]]
		+	[[Category: Affimer]]
		+	[[Category: Protein binding]]

OCA: Protected "6hjl" [edit=sysop:move=sysop]

OCA — Wed, 12 Sep 2018 06:04:20 GMT

Protected "6hjl" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:04, 12 September 2018

OCA: New page: '''Unreleased structure''' The entry 6hjl is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Wed, 12 Sep 2018 06:04:19 GMT

New page: '''Unreleased structure''' The entry 6hjl is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6hjl is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]

6hjl - Revision history

OCA at 09:37, 18 March 2020

OCA: Protected "6hjl" [edit=sysop:move=sysop]

OCA: New page: '''Unreleased structure''' The entry 6hjl is ON HOLD Authors: Description: Category: Unreleased Structures